Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: Study to Evaluate the Cardiac Safety of TAS-102 in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating cardiac safety of TAS-102 in patients with advanced solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: Study Comparing the Pharmacokinetics of FTD as a Component of TAS-102 With FTD Alone [Phase 1]
Phase 1 pharmacokinetic study comparing trifluorothymidine (FTD) when administered as part of TAS-102 versus FTD alone in patients with adva…
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: Dose-escalating, Safety, Tolerability and PK Study of TAS-119 in Combination With Paclitaxel in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 dose-escalation study evaluating TAS-119 in combination with paclitaxel in patients with advanced solid tumors. The trial status is …
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CLINICAL_TRIALS trial_result · 2024-09-05Clinical Trial Update: Study of the Mass Balance of Oral FTD and TPI as Components of TAS-102 in Patients With Advanced Solid Tumors [Phase 1]
This Phase 1 study assesses the mass balance and pharmacokinetics of the TAS-102 components trifluridine and tipiracil in patients with adva…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: An Investigation of TAS-119 Monotherapy [Phase 1]
The update covers TAS-119 given as monotherapy in a Phase 1 trial for patients with advanced solid tumors; the study (NCT02448589) sponsored…
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: A Study of ZL-1211 in Patients With Advanced Solid Tumor [Phase 1]
A Phase 1 study of ZL-1211 in patients with advanced solid tumors has completed, with the update noting the trial status.
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: AZD9150 Plus Durvalumab Alone or in Combination With Chemotherapy in Patients With Advanced, Solid Tumours and in Patients With Non-Small-Cell Lung Cancer [Phase 1]
Phase 1 trial update evaluating AZD9150 alone or with durvalumab, with or without chemotherapy, in patients with advanced solid tumors and n…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Feasibility and Safety of Acupuncture in the Prevention of Late Irinotecan-related Diarrhea in Pediatric Patients [NA]
A completed clinical trial evaluating the feasibility and safety of acupuncture to prevent late irinotecan-related diarrhea in children with…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Study to Assess the Safety of Escalating Doses of AT13387 in Patients With Metastatic Solid Tumors [Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating escalating doses of AT13387 (onalespib) in patients with met…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Dose Escalation and Efficacy Study of mRNA-2416 for Intratumoral Injection Alone and in Combination With Durvalumab for Participants With Advanced Malignancies [Phase 1, Phase 2]
This clinical trial update reports dose-escalation and preliminary efficacy findings for intratumoral mRNA-2416 as a standalone therapy and …
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: A Phase I Study of NTQ1062 in Chinese Patients With Advanced Solid Tumors [Phase 1]
A Phase I clinical trial of NTQ1062 in Chinese patients with solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2024-07-25Clinical Trial Update: Study of AG-270 in Participants With Advanced Solid Tumors or Lymphoma With MTAP Loss [Phase 1]
Phase 1 study of AG-270 in participants with MTAP-deleted advanced solid tumors or lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2024-07-24Clinical Trial Update: Study of MK-2118 Administered as Intratumoral Injection as Monotherapy and in Combination With Pembrolizumab (MK-3475) or by Subcutaneous Injection in Combination With Pembrolizumab in the Treatment of Adults With Advanced/Metastatic Solid Tumors or Lymphomas (MK-2118-001) [Phase 1]
Phase 1 study of MK-2118 given as intratumoral monotherapy or in combination with pembrolizumab, and of subcutaneous MK-2118 in combination …
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CLINICAL_TRIALS trial_result · 2024-07-22Clinical Trial Update: A Study of GRC 54276 in Participants With Advanced Solid Tumors and Lymphomas. [Phase 1]
A Phase 1 study evaluating GRC 54276 in participants with advanced solid tumors and lymphomas is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: A Multiple Ascending Dose Study of Milademetan in Subjects With Advanced Solid Tumors or Lymphomas [Phase 1]
Phase 1 multiple ascending dose study of milademetan in adults with advanced solid tumors or lymphomas has completed, and results have been …
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: A Study of ATG-018 (ATR Inhibitor) Treatment in Patients With Advanced Solid Tumors and Hematological Malignancies [Phase 1]
Phase 1 study of ATG-018, an ATR inhibitor, in patients with advanced solid tumors and hematological malignancies has been terminated.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Chiauranib for Advanced Solid Malignant Tumors and Relapsed/Refractory SCLC. [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Chiauranib in patients with small cell lung cancer and advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Phase I, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Solid Tumors, Multiple Myeloma, or Lymphoma [Phase 1]
DCR-MYC, an investigational therapy, was evaluated in a Phase I multicenter dose-escalation study in patients with solid tumors, multiple my…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: ⁸⁹Zr-Df-IAB22M2C (CD8 PET Tracer) for PET/CT in Patients With Metastatic Solid Tumors [Phase 2]
Phase 2 trial updates on a CD8-targeted PET tracer 89Zr-Df-IAB22M2C for PET/CT in patients with metastatic solid tumors, with results posted…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: A Study of Mirdametinib on Its Own or in Combination With Fulvestrant in People With Solid Tumor Cancer [Phase 1, Phase 2]
Memorial Sloan Kettering Cancer Center conducted a Phase 1/2 trial of Mirdametinib alone or with Fulvestrant in solid tumors including breas…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: GIC-102, Intravenous Allogeneic NK Cells, in Subjects With Advanced Solid Cancers and R/R Hematologic Malignancies [Phase 1, Phase 2]
GIC-102, an intravenously administered allogeneic NK cell therapy, is being evaluated in Phase 1/Phase 2 trials for advanced solid tumors an…
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CLINICAL_TRIALS trial_result · 2024-07-08Clinical Trial Update: GH55 for Advanced Cancers With MAPK Mutations: A Study on Safety and Early Results [Phase 1, Phase 2]
This clinical trial update covers GH55 in Phase 1/2 for advanced solid tumors with MAPK pathway mutations, focusing on safety and early resu…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: First-In-Human Dose-Escalation Study of STP1002 in Patients With Advanced-Stage Solid Tumors [Phase 1]
This update reports the completion of a first-in-human dose-escalation Phase 1 trial of STP1002 in patients with solid tumors, assessing saf…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Precision Medicine for Patients With Identified Actionable Mutations [Phase 2]
A Phase 2 precision medicine trial for patients with identified actionable mutations in solid tumors, lymphoma, and multiple myeloma was ter…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Leflunomide for the Treatment of Severe COVID-19 in Patients With a Concurrent Malignancy [Phase 1, Phase 2]
This document reports completion and results posting for a Phase 1/2 study evaluating leflunomide as a treatment for severe COVID-19 in pati…