Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: An Engineered Sirpα Fused to Anti-Pd-L1 And Tgf-β Fusion Protein (HCB301) in Subjects With Selected Advanced Tumors [Phase 1]
A Phase 1 clinical trial evaluating HCB301, an engineered Sirpα fusion with anti-PD-L1 and TGF-β activity, in patients with selected advance…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Combination of Two Anti-cancer Drugs, Peposertib (M3814) and Tuvusertib (M1774) for Advanced Solid Tumors [Phase 1]
A Phase 1 trial by the National Cancer Institute is evaluating the combination of Peposertib (M3814) and Tuvusertib (M1774) in patients with…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors [Phase 1]
Open-label Phase 1 clinical trial evaluating BBO-10203 in adults with advanced, metastatic solid tumors; currently recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01) [Phase 1, Phase 2]
A Phase 1/2 study evaluating patritumab deruxtecan in pediatric participants with relapsed or refractory solid tumors; recruitment is ongoin…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing How the Body Responds to the Drug CBX-12 in Patients With Advanced Solid Cancers [Phase 1]
Phase 1 clinical trial evaluating CBX-12 in adults with advanced solid tumors, including metastatic disease, is currently recruiting. The st…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Trial to Investigate the Safety of E303 in Participants With Advanced Refractory Solid Tumors [Phase 1]
This document reports an ongoing Phase 1 clinical trial to assess the safety of E303 in participants with advanced refractory solid tumors, …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial to evaluate safety, pharmacokinetics, and preliminary efficacy of ONC 841 in patients with advanced solid tumors; cur…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Collaborative Intervention for Improving Cancer Pain Management in Cancer Survivors [NA]
An ongoing Mayo Clinic trial tests a collaborative intervention to improve cancer pain management in cancer survivors and is currently recru…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study of TRX-920 for Patients With Advanced Solid Tumors [Phase 1]
TaiRx, Inc. is recruiting for a Phase 1 study of TRX-920 in patients with advanced solid tumors.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study of ZE94-0605 in Patients With Advanced Solid Tumors, With Dose Expansion Cohorts. [Phase 1]
Phase 1 clinical trial update for ZE94-0605 in patients with advanced solid tumors, including dose expansion cohorts. The study is not yet r…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor Patients (South Korea) [Phase 1]
Phase 1 trial of OTS-412, a recombinant oncolytic vaccinia virus, in treatment-refractory solid tumor patients in South Korea; currently rec…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacokinetics, and Preliminary Efficacy of FS-8002 [Phase 1]
Phase 1 clinical trial update for FS-8002 in advanced solid tumors. The study assesses safety, tolerability, pharmacokinetics, and prelimina…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study to Evaluate the Mass Balance, Metabolism, Elimination, and Drug Levels of [14C]-BMS-986504 (MRTX1719) in Participants With Advanced Solid Tumors With Homozygous Methylthioadenosine Phosphorylase Deletion [Phase 1]
Phase 1 study to evaluate mass balance, metabolism, elimination, and drug levels of radiolabeled BMS-986504 (MRTX1719) in participants with …
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors [Phase 1, Phase 2]
This clinical trials update notes ongoing Phase 1/2 studies of EIK1005, a Werner helicase inhibitor, as monotherapy and in combination with …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study evaluating the safety, pharmacokinetics, and anti-tumor activity of VVD-133214 as monotherapy and in combination in participan…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials [Phase 4]
The FLOTILLA Phase 4 trial update describes continued access to encorafenib and binimetinib for participants who previously enrolled in rela…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Phase 1 Study of 177Lu-IM-3050 in Participants With Advanced Cancer [EARLY_Phase 1]
A Phase 1 clinical trial update for the radiopharmaceutical 177Lu-IM-3050 evaluating safety and dosing in participants with solid tumors; th…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: JY016 Injection in Patients With Advanced Solid Tumors Expressing EGFR [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study of JY016 for advanced solid tumors expressing EGFR, with the trial currently NO…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A First-in-Human Study of BGB-C354 Alone and in Combination With Tislelizumab in Participants With Advanced Solid Tumors [Phase 1]
This is a first-in-human Phase 1 trial evaluating BGB-C354 alone and in combination with tislelizumab in participants with advanced solid tu…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Worldwide Cancer Registry Enrolling Participants Profiled With a Next-Generation Sequencing Test
Roche is sponsoring a global cancer registry enrolling participants with solid tumors who will be profiled using a next-generation sequencin…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer [Phase 1]
Phase 1 clinical trial evaluating autologous T-cells engineered to target KRAS mutations in combination with a KRAS-directed vaccine for met…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations [Phase 2]
Phase 2 clinical trial update announcing the evaluation of FORE8394 in participants with cancers harboring BRAF alterations, including high-…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain [Phase 3]
Phase 3 trial comparing longer-duration radiation therapy versus standard radiation therapy for patients with cancer that has spread to the …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements [Phase 1, Phase 2]
Phase 1/2 study of Repotrectinib in patients with advanced or metastatic solid tumors that harbor ALK, ROS1, or NTRK1-3 gene rearrangements;…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: FL-261 Imaging for Cancer Diagnosis and Staging
A clinical trial named FL-261 for imaging-based cancer diagnosis and staging is currently recruiting, studying its use across multiple cance…