Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2018-03-16Clinical Trial Update: An Open-label Phase I/II Clinical Trial of PT-112 Injection for Advanced Solid Tumors and Advanced Hepatocellular Carcinoma [Phase 1, Phase 2]
Open-label Phase 1/2 trial of PT-112 Injection in patients with advanced solid tumors and advanced hepatocellular carcinoma.
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CLINICAL_TRIALS research · 2017-11-21Clinical Trial Update: Assess the Oral Bioavailability of a New ABT-263 Formulation in Subjects With Cancer [Phase 1]
This Phase 1 study assesses the oral bioavailability of a new ABT-263 (navitoclax) formulation in cancer patients.
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CLINICAL_TRIALS research · 2017-11-21Clinical Trial Update: Pharmacokinetic Study To Evaluate Effect of Food and Diurnal Variation on ABT-869 [Phase 1]
Phase 1 pharmacokinetic study of ABT-869 (linifanib) evaluating the effects of food and diurnal variation on drug exposure in adults with ad…
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CLINICAL_TRIALS research · 2017-08-24Clinical Trial Update: Study to Evaluate the Safety, Preliminary Efficacy and Pharmacokinetics of 3810 [Phase 1]
Phase 1 clinical trial evaluating the safety, preliminary efficacy and pharmacokinetics of the investigational agent 3810 in patients with a…
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CLINICAL_TRIALS research · 2017-07-02Clinical Trial Update: Pharmacokinetic Studies Participation Survey
This completed NCI-sponsored trial update covers participation in pharmacokinetic studies for patients with relapsed solid tumors and leukem…
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CLINICAL_TRIALS research · 2017-03-03Clinical Trial Update: Open Label Study of DS-5573a [Phase 1]
Open-label Phase 1 study of DS-5573a by Daiichi Sankyo in patients with advanced solid malignant tumors has been terminated.
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CLINICAL_TRIALS research · 2017-02-14Clinical Trial Update: Phase I Study of CS-7017 and Bexarotene [Phase 1]
Phase I trial of CS-7017 in combination with Bexarotene for solid tumors, lymphoma, and multiple myeloma has been terminated.
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CLINICAL_TRIALS research · 2016-01-28Clinical Trial Update: Treatment of Chemotherapy Refractory Human Epidermalgrowth Factor Receptor-2( HER-2) Positive Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial update from Chinese PLA General Hospital evaluating treatment of chemotherapy-refractory HER2-positive advanced s…
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CLINICAL_TRIALS research · 2016-01-28Clinical Trial Update: Lower Dose Decitabine Based Therapy in Patients With Refractory and/or Chemotherapy Resistant Solid Tumors or B Cell Lymphomas [Phase 1, Phase 2]
Clinical trial update on a lower-dose decitabine-based therapy for patients with refractory or chemotherapy-resistant solid tumors and B-cel…
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CLINICAL_TRIALS research · 2015-08-27Clinical Trial Update: Concurrent School Attendance And Cancer Therapy: The Experiences of 6-12 Year Old Pediatric Oncology Patients
This clinical trial update describes the experiences of 6- to 12-year-old pediatric cancer patients balancing school attendance with ongoing…
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CLINICAL_TRIALS research · 2015-08-21Clinical Trial Update: Safety Study of Pharmacokinetics of XL888 in Adults With Solid Tumors [Phase 1]
Phase 1 safety and pharmacokinetics study of XL888 in adults with solid tumors was terminated.
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CLINICAL_TRIALS research · 2015-08-13Clinical Trial Update: Analysis of Data Collected in the European Group for Blood and Marrow Transplantation (EBMT) Registry for Off-Label Transplant Use of Plerixafor
Analysis of EBMT registry data evaluates off-label use of plerixafor in hematopoietic cell transplantation, summarizing indications and obse…
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CLINICAL_TRIALS research · 2015-03-24Clinical Trial Update: A Phase Ia, Dose Escalation Study of Humanized Anti-VEGF Monoclonal Antibody (Sevacizumab) Injection in Patients With Advanced or Metastatic Solid Tumors [Phase 1]
This entry describes a Phase Ia dose-escalation study of Sevacizumab, a humanized anti-VEGF monoclonal antibody, in patients with advanced o…
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CLINICAL_TRIALS research · 2014-10-08Clinical Trial Update: Safety Study of CD3/CD19 Depleted Haploidentical Stem Cells [Phase 1, Phase 2]
A Phase 1/2 safety study evaluating CD3/CD19 depleted haploidentical stem cell transplants in pediatric patients with acute leukemia, aplast…
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CLINICAL_TRIALS research · 2014-08-27Clinical Trial Update: Dose Escalation and Pharmacokinetic Study of Paclitaxel Liposome Injection in Treating Patients With Advanced Solid Tumor After Failure From Conventional Treatments [Phase 4]
Phase 4 clinical trial update evaluating dose escalation and pharmacokinetics of paclitaxel liposome injection in patients with advanced sol…
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CLINICAL_TRIALS research · 2014-08-20Clinical Trial Update: Feasibility Study for Imaging of Peripheral Tumors With a High-Resolution PET Imaging System [NA]
This document reports a completed feasibility study evaluating high-resolution PET imaging for peripheral solid tumors.
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CLINICAL_TRIALS research · 2014-07-14Clinical Trial Update: Patient-Reported Outcomes Version of Common Terminology Criteria (CTCPRO) Cognitive Debriefing
This update reports progress on cognitive debriefing for CTCPRO, a patient-reported outcomes version of CTCAE used to assess cancer-related …
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CLINICAL_TRIALS research · 2013-09-17Clinical Trial Update: Paclitaxel, Folic Acid, and Lometrexol in Treating Patients With Locally Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 clinical trial update evaluating the combination of paclitaxel, folic acid, and lometrexol in adults with locally advanced or metast…
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CLINICAL_TRIALS research · 2013-09-17Clinical Trial Update: Screening to Predict Weight Loss in Patients With Cancer [NA]
Clinical trial update on screening to predict weight loss in cancer patients; the current status is unknown.
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CLINICAL_TRIALS research · 2013-08-30Clinical Trial Update: EVESOR: a Phase 1 Trial of Everolimus and Sorafenib [Phase 1]
This document describes a Phase 1 clinical trial (EVESOR) evaluating Everolimus in combination with Sorafenib for patients with metastatic o…
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CLINICAL_TRIALS research · 2013-06-03Clinical Trial Update: A Clinical Pharmacodynamic and Pharmacogenetic Study of OPB-51602 in Patients With Advanced Solid Tumours
A pharmacodynamic and pharmacogenetic study of OPB-51602 in patients with advanced solid tumors; current trial status is unknown.
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CLINICAL_TRIALS research · 2012-07-19Clinical Trial Update: Phase I Study of Oral Darinaparsin (ZIO-101-C)in Advanced Solid Tumors and Non-Hodgkin's Lymphomas [Phase 1]
This is a Phase I clinical trial update of oral darinaparsin (ZIO-101-C) in patients with advanced solid tumors and Non-Hodgkin lymphoma; no…
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CLINICAL_TRIALS research · 2012-05-01Clinical Trial Update: A Study to Determine the Absorption, Distribution, Metabolism, and Excretion of LBH589 [Phase 1]
A Phase 1 study to determine the absorption, distribution, metabolism, and excretion of LBH589 (panobinostat) in cancer patients with advanc…
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CLINICAL_TRIALS research · 2012-02-15Clinical Trial Update: Neutrophil Extracellular Traps (NETs) Formation Following Chemotherapy and Their Role in Antitumor Activity
A clinical trial update examining how neutrophil extracellular traps formed after chemotherapy may contribute to antitumor activity in pedia…
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CLINICAL_TRIALS research · 2012-01-13Clinical Trial Update: HLA-haploidentical Hematopoietic Stem Cell Transplantation for Children and Adolescents With Acute Leukemia, Myelodysplastic Syndrome and Solid Tumors [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial evaluating HLA-haploidentical hematopoietic stem cell transplantation in children and adolescents with acute …