Solid Tumors
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: A Study to Evaluate the Safety and Tolerability of ETC-1922159 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumours [Phase 1]
This document provides an update on a Phase 1 clinical trial evaluating ETC-1922159 as a single agent and in combination with pembrolizumab …
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: Safety and Efficacy of KLS-1 Monotherapy in Malignant Neoplasms [Phase 1, Phase 2]
A Phase 1/Phase 2 trial evaluating KLS-1 as a monotherapy for malignant neoplasms, including chronic lymphocytic leukemia and solid tumors; …
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: Expanded Access to Provide GL-ONC1 for the Treatment of Advanced Cancers With No Standard of Care
Expanded access program for GL-ONC1 in patients with advanced solid tumors and acute myeloid leukemia is no longer available.
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: Efficacy and Safety of Duloxetine in Chinese Solid Tumor Patients with Taxanes-induced Painful Peripheral Neuropathy [Phase 2]
Phase 2 trial assessing the efficacy and safety of duloxetine for taxanes-induced painful peripheral neuropathy in Chinese patients with sol…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Phase I/II Study of XZP-3287 in Metastasis Solid Tumors [Phase 1, Phase 2]
This is a status update for an ongoing Phase I/II trial of XZP-3287 in metastatic solid tumors and advanced breast cancer, currently active …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: ENB003 Plus Pembrolizumab Phase 1b/2a in Solid Tumors [Phase 1, Phase 2]
A Phase 1b/2a trial evaluating ENB003 in combination with pembrolizumab for various solid tumors, including melanoma, ovarian cancer, pancre…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Clinical Study of the Safety, Tolerability, Pharmacokinetics, and Initial Efficacy of HRS-4508 Monotherapy in Patients With Advanced or Metastatic Solid Tumors [Phase 1]
This is a Phase 1 clinical study overview evaluating HRS-4508 monotherapy in patients with advanced or metastatic solid tumors, focusing on …
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CLINICAL_TRIALS research · 2024-07-25Clinical Trial Update: Understanding Communication in Healthcare to Achieve Trust (U-CHAT)
This entry provides an update on a completed clinical trial (U-CHAT) led by St. Jude Children's Research Hospital, focused on communication …
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CLINICAL_TRIALS research · 2024-07-19Clinical Trial Update: CPCT-02 Biopsy Protocol [NA]
This document provides an update to the CPCT-02 biopsy protocol for a trial involving solid tumors and metastatic disease, with the study st…
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CLINICAL_TRIALS research · 2024-07-08Clinical Trial Update: Study of LTC004 Combine With Toripalimab in Patient With Solid Tumors Resistant to Immunotherapy [Phase 2]
An ongoing Phase 2 trial is evaluating LTC004 in combination with toripalimab for patients with advanced solid tumors resistant to immunothe…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: Engineered TILs/CAR-TILs to Treat Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating engineered tumor-infiltrating lymphocytes (TILs) and CAR-TILs for advanced solid tumors, sponsored by the …
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: A Phase IB/II Clinical Study of SHR-9839 for Injection Combined With Other Anti-tumor Therapies in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update notes a Phase Ib/II study to evaluate SHR-9839 in combination with other anti-tumor therapies for patients with a…
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Development and Application Study of ePRO Software for Managing Cancer Patients Throughout the Treatment Period [NA]
Clinical trials update describing the development and application of an electronic patient-reported outcome (ePRO) software to manage cancer…
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CLINICAL_TRIALS research · 2024-06-18Clinical Trial Update: Clinical Study of TROP-2 PET/CT for Noninvasive Diagnosis of Solid Tumors [NA]
A clinical trial is evaluating a TROP-2 targeted PET/CT imaging method for noninvasive diagnosis of solid tumors; recruitment is ongoing.
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Study Evaluating ISM8207 in Participants With Advanced Solid Tumors and Relapsed/Refractory B-Cell Lymphoma [Phase 1]
Phase 1 clinical trial evaluating ISM8207 in participants with advanced solid tumors or relapsed/refractory B-cell lymphoma, currently recru…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: U87 CART in Treatment of Advanced Solid Tumor [Phase 1]
Phase 1 clinical trial update for U87 CART therapy in adults with advanced solid tumors, including pancreatic cancer; trial status is UNKNOW…
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: Clinical Efficacy of Tumour Treatment Vaccine (TTV) Combined With PD-1 in the Treatment of Relapsed Refractory Advanced Solid Tumours [NA]
A clinical trial evaluating Tumour Treatment Vaccine (TTV) in combination with a PD-1 inhibitor for relapsed/refractory advanced solid tumor…
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CLINICAL_TRIALS research · 2024-05-21Clinical Trial Update: Study of eFT226 in Subjects With Selected Advanced Solid Tumor Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating eFT226 in adults with selected advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: A Study of FDA022-BB05 in Subjects With Advanced Solid Malignant Tumors [Phase 1]
A Phase 1 trial evaluating FDA022-BB05 in patients with advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2024-05-14Clinical Trial Update: TR115 in Patients With Relapsed / Refractory Non-Hodgkin's Lymphoma or Advanced Solid Tumors [Phase 1]
A Phase 1 clinical trial of TR115 is currently recruiting in patients with relapsed/refractory non-Hodgkin's lymphoma and advanced solid tum…
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CLINICAL_TRIALS research · 2024-05-01Clinical Trial Update: Trial to Evaluate Safety, PD & PK of IV Study Drug, QN-302, in Pts w/ Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 clinical trial update evaluating safety, pharmacodynamics, and pharmacokinetics of the IV study drug QN-302 in patients with advance…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: A Study of RC88 Combined With Sintilimab for Advanced Solid Tumours [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating RC88 in combination with Sintilimab for advanced solid tumors, and the study is currently recruitin…
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CLINICAL_TRIALS research · 2024-04-15Clinical Trial Update: Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TJ107 in Chinese Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of TJ107 in Chinese patients with advanced solid tumo…
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CLINICAL_TRIALS research · 2020-03-31Clinical Trial Update: MEtoclopramide, DExamethasone or Axoli to Prevent or Delay Chemotherapy-induced Nausea and Vomiting in Moderately Emetogenic Non-AC-based Chemotherapy [Phase 3]
Phase 3 clinical trial evaluating metoclopramide, dexamethasone, or Axoli to prevent or delay chemotherapy-induced nausea and vomiting in mo…
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CLINICAL_TRIALS research · 2018-03-21Clinical Trial Update: Safety and Efficacy of an Anticancer Medication Combined With Immune Cells in Subjects With Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating the safety and preliminary efficacy of a cancer medication combined with immune cells in subjects with adv…