Solid Tumors

• CLINICAL_TRIALS research · 2025-04-25
  Clinical Trial Update: Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetics of MPD-1 in Patients With Advanced Solid Tumor [Phase 1]

  A Phase 1 trial is evaluating the safety, tolerability, and pharmacokinetics of MPD-1 in patients with advanced solid tumors and is currentl…

• CLINICAL_TRIALS research · 2025-04-23
  Clinical Trial Update: Application of the sG8 Scale in Real-World Geriatric Oncology Patients

  A clinical trial update describing the real-world use of the sG8 scale to assess geriatric oncology patients with solid tumors; the study is…

• CLINICAL_TRIALS research · 2025-04-17
  Clinical Trial Update: Aprepitant in the Management of Immune Checkpoint Inhibitors Pruritus in Solid Cancer Patients [Phase 1]

  This Phase 1 clinical trial evaluates aprepitant for management of pruritus caused by immune checkpoint inhibitors in patients with solid tu…

• CLINICAL_TRIALS research · 2025-04-17
  Clinical Trial Update: A Study of QLM2011 in Subjects With Advanced Solid Tumors [Phase 1]

  Phase 1 clinical trial update for QLM2011 in subjects with advanced solid tumors; the study is not yet recruiting.

• CLINICAL_TRIALS research · 2025-04-15
  Clinical Trial Update: Telpegfilgrastim vs Filgrastim for Secondary Prevention of Chemotherapy-Induced Neutropenia in Pediatric Solid Tumors [Phase 2]

  Phase 2 clinical trial update comparing telpegfilgrastim with filgrastim for secondary prevention of chemotherapy-induced neutropenia in ped…

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• CLINICAL_TRIALS research · 2025-04-15
  Clinical Trial Update: A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of BA1301 in Advanced Solid Tumors. [Phase 1]

  An early-phase trial update describing safety, tolerability, pharmacokinetics and preliminary efficacy of BA1301 in patients with advanced s…

• CLINICAL_TRIALS research · 2025-04-09
  Clinical Trial Update: Phase Ib Trial of HS-20117 in Combination With Other Drugs in Advanced Solid Tumors [Phase 1]

  This document describes a Phase Ib trial of HS-20117 in combination with other drugs for advanced solid tumors, currently recruiting.

• CLINICAL_TRIALS research · 2025-04-08
  Clinical Trial Update: First-in-human Trial of PhOx430, a First-in-class Acetylglucosaminyltransferase V Inhibitor, in Advanced Solid Tumours [Phase 1]

  First-in-human Phase 1 trial of PhOx430, a first-in-class Acetylglucosaminyltransferase V inhibitor, assessed in advanced solid tumors; the …

• CLINICAL_TRIALS research · 2025-04-08
  Clinical Trial Update: Granzyme B-targeted PET Imaging Monitoring Tumor Responses to Immunotherapy

  This clinical trial update describes a study using Granzyme B-targeted PET imaging to monitor tumor responses to immunotherapy, which is cur…

• CLINICAL_TRIALS research · 2025-04-02
  Clinical Trial Update: Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal

  Mayo Clinic is conducting a study to analyze blood and tumor tissue to identify diagnostic biomarkers in patients with metastatic cancer who…

• CLINICAL_TRIALS research · 2025-04-01
  Clinical Trial Update: A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Biologic Effect of VG2025 in Patients with Solid Tumors [Phase 1]

  A Phase 1 clinical study to evaluate the safety, tolerability, pharmacokinetics and biologic effect of VG2025 in patients with advanced mali…

• CLINICAL_TRIALS research · 2025-04-01
  Clinical Trial Update: Combination Therapy of Personalized mRNA-0217 Vaccines and Pembrolizumab in Patients With Advanced Solid Tumors [EARLY_Phase 1]

  A Phase 1 trial is evaluating a combination of a personalized mRNA-0217 vaccine with pembrolizumab in patients with advanced solid tumors an…

• CLINICAL_TRIALS research · 2025-03-26
  Clinical Trial Update: A Phase I Trial of Tumor-Associated Lymph Node T-Cell Injection With Advanced Malignant Solid Tumors [Phase 1]

  Phase I trial assessing Tumor-Associated Lymph Node T-Cell Injection alone or with Serplulimab for patients with advanced malignant solid tu…

• CLINICAL_TRIALS research · 2025-03-21
  Clinical Trial Update: Radiosurgery Before Surgery for the Treatment of Brain Metastases [EARLY_Phase 1]

  This document reports an early-phase clinical trial evaluating radiosurgery before surgery for brain metastases, with the study currently ac…

• CLINICAL_TRIALS research · 2025-03-20
  Clinical Trial Update: First-in-human Study of OT-A201 in Patients With Selected Hematological Malignancies and Solid Tumors [Phase 1]

  First-in-human Phase 1 trial evaluating OT-A201 in patients with selected hematologic malignancies and solid tumors; currently recruiting.

• CLINICAL_TRIALS research · 2025-03-19
  Clinical Trial Update: A Phase I Study of LXP1788 Injection with Advanced Solid Tumors. [Phase 1]

  This Phase I trial is evaluating the safety and tolerability of LXP1788 Injection in adults with advanced solid tumors and is currently recr…

• CLINICAL_TRIALS research · 2025-03-19
  Clinical Trial Update: Clinical Trial of SYS6010±SYH2051 Versus Chemotherapy in Advanced Breast Cancer and Other Solid Tumors [Phase 1, Phase 2]

  Phase 1/2 clinical trial comparing SYS6010±SYH2051 versus chemotherapy in advanced breast cancer and other solid tumors; the study is not ye…

• CLINICAL_TRIALS research · 2025-03-05
  Clinical Trial Update: Supportive Care Needs of Former Child, AYA Cancer Patients, and of Their Parents: Evaluation During Long-term Follow-up

  This clinical trial update reports on evaluating the supportive care needs of former pediatric, adolescent and young adult cancer patients a…

• CLINICAL_TRIALS research · 2025-03-05
  Clinical Trial Update: A Trial of SHR-4849 in Advanced Solid Tumors [Phase 1]

  Clinical trial update for SHR-4849 in advanced solid tumors describing a Phase 1 study that is currently recruiting.

• CLINICAL_TRIALS research · 2025-03-03
  Clinical Trial Update: First in Human Study of EMB-07 in Locally Advanced/Metastatic Solid Tumors or Relapse/Refractory Lymphoma [Phase 1]

  First-in-human Phase 1 study of EMB-07 in patients with advanced/metastatic solid tumors or relapsed/refractory lymphoma is currently recrui…

• CLINICAL_TRIALS research · 2025-02-26
  Clinical Trial Update: APG-115 in Combination With PD-1 Inhibitor in Patients With Advanced Liposarcoma or Advanced Solid Tumors [Phase 1, Phase 2]

  Clinical trial update describing an ongoing Phase 1/2 study of APG-115 in combination with a PD-1 inhibitor for patients with liposarcoma or…

• CLINICAL_TRIALS research · 2025-02-26
  Clinical Trial Update: APG-2449 Monotherapy or in Combination With PLD in Patients With Platinum-resistant Recurrent OC or Advanced ST [Phase 1]

  Phase 1 trial of APG-2449 as monotherapy or with pegylated liposomal doxorubicin (PLD) in platinum-resistant recurrent ovarian cancer and ad…

• CLINICAL_TRIALS research · 2025-02-24
  Clinical Trial Update: TGRX-1942 Chinese Phase I for Advanced Solid Tumor And/or Relapsed/Refractory Hematologic Malignancies [Phase 1]

  A Phase 1 study of TGRX-1942 for advanced solid tumors and/or relapsed/refractory hematologic malignancies is currently recruiting in China.

• CLINICAL_TRIALS research · 2025-02-07
  Clinical Trial Update: A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CD-001 in Patients With Advanced Solid Tumors [Phase 1]

  A Phase 1 clinical trial is evaluating CD-001 to assess safety, tolerability, pharmacokinetics, and preliminary efficacy in adults with adva…

• CLINICAL_TRIALS research · 2025-02-06
  Clinical Trial Update: Study on the Safety and Efficacy of Intravenous Administration of IDOV-SAFETM in the Treatment of Advanced Solid Tumors [EARLY_Phase 1]

  A Phase 1 clinical trial is evaluating intravenous IDOV-SAFETM in patients with advanced solid tumors and is currently recruiting to assess …