Solid Tumors
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: IMA402 T Cell-Engaging Receptor Molecule (TCER®) in Recurrent and/or Refractory Solid Tumors [Phase 1, Phase 2]
Immatics Biotechnologies reports its TCER molecule IMA402 is being evaluated in Phase 1/2 trials for recurrent and/or refractory solid tumor…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Tumor Molecular Profiling in Early Phase Clinical Trials
The document describes an early-phase clinical trial program using tumor molecular profiling in patients with solid tumors and lymphoma, whi…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors [Phase 1, Phase 2]
Phase Ib/II clinical study evaluating HLX43 in combination with serplulimab for advanced/metastatic solid tumors is currently recruiting. Th…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Phase 1 Study of BB102 in Participants With Advanced Solid Tumors [Phase 1]
This clinical trial update notes that BB102 is being studied in a Phase 1 trial for participants with advanced solid tumors and is currently…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Patient Perceptions of the Relational Empathy of Healthcare Practitioners From the Department of Emergency Medicine During the COVID-19 Pandemic [NA]
ClinicalTrials.gov update from MD Anderson Cancer Center describing a study on patient perceptions of the relational empathy of emergency de…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies [Phase 1, Phase 2]
Clinical trial update for BT8009-100 in nectin-4 expressing advanced malignancies (Phase 1/2) with status ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: The Effect of Exercise and Nicotinamide Riboside Muscle Health and Insulin Resistance in Survivors of Childhood Cancer [NA]
This clinical trial update describes a study evaluating the effects of exercise and nicotinamide riboside on muscle health and insulin resis…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Formulating Expert Consensus Guidelines in Cancer Care Using the Delphi Method
This clinical trial update from MD Anderson outlines a study to formulate expert consensus cancer care guidelines using the Delphi method; t…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of DCR-PDL1 in Adults With Solid Tumors [Phase 1]
This is an ongoing Phase 1 clinical trial evaluating safety, tolerability, and pharmacokinetics of DCR-PDL1 in adults with solid tumors. The…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Indocyanine Green (ICG) Guided Tumor Resection [Phase 1]
This clinical trial entry describes a Phase 1 study evaluating Indocyanine Green (ICG) guided tumor resection in patients with neoplastic di…
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CLINICAL_TRIALS research · 2025-11-03Clinical Trial Update: A Modular Phase 1/2 Study With CT7439 in Participants With Solid Malignancies [Phase 1, Phase 2]
A modular Phase 1/2 clinical trial of CT7439 for solid malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab [Phase 1]
A Phase 1 clinical trial update shows ABBV-400 alone or with bevacizumab being studied in adults with advanced solid tumors, including non-s…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab [Phase 1, Phase 2]
Strand Therapeutics is conducting a Phase 1/2 trial of intratumoral STX-001 in advanced solid tumors, as monotherapy or in combination with …
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: Investigating the Impact of Proactive Palliative Care
A clinical trial update from Memorial Sloan Kettering Cancer Center describes a study on the impact of proactive palliative care for patient…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Parental Attitudes and Beliefs Regarding Risks Associated With Opioid Use in Children With Cancer
An ongoing MD Anderson Cancer Center study investigates parental attitudes toward opioid risks in pediatric cancer patients; the trial is cu…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: A Study of T-DXd as Monotherapy or in Combination With Anti-cancer Agents in Patients With Selected HER2-expressing Tumors [Phase 2]
Phase 2 clinical trial evaluating trastuzumab deruxtecan (T-DXd) as monotherapy or in combination with anti-cancer agents for selected HER2-…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid Tumors [Phase 1]
This Phase 1 trial assesses ABBV-706 alone or in combination with budigalimab, cisplatin, or carboplatin in adults with advanced solid tumor…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Next Generation Sequencing of Normal Tissues Prospectively in Pediatric Oncology Patients
St. Jude Children's Research Hospital is conducting a prospective study to perform next-generation sequencing on normal tissues in pediatric…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Imaging of Solid Tumors Using DLL3 SPECT [EARLY_Phase 1]
Early Phase 1 clinical trial evaluating DLL3 SPECT imaging for solid tumors, including castration-resistant prostate cancer and neuroendocri…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Personalized KXV01 TCR Lentinvivo Injection as the Therapy for Advanced Solid Tumors [Phase 1]
Phase 1 trial update for a personalized KXV01 TCR Lentinvivo Injection intended to treat advanced solid tumors; the study is not yet recruit…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Bergonie Institut Profiling : Fighting Cancer by Matching Molecular Alterations and Drugs in Early Phase Trials [NA]
Clinical trial update from Institut Bergonié describes profiling patients with cancer to match molecular alterations with experimental drugs…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Study of TTX-MC138 in Subjects With Advanced Solid Tumors [Phase 1, Phase 2]
This document provides a clinical trial update for TTX-MC138 in adults with advanced solid tumors, covering Phase 1 and Phase 2 studies that…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases [Phase 1]
This update describes the first-in-human Phase 1 trial of AO-252, an oral TACC3 protein-protein interaction inhibitor, in patients with adva…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: A Study of GNC-039, a Tetra-specific Antibody, in Participants With Relapsed/Refractory or Metastatic Solid Tumors [Phase 1]
Phase 1 trial update for GNC-039, a tetra-specific antibody, in relapsed/refractory or metastatic solid tumors; currently recruiting.
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: Personalized KXV01 TCR Lentinvivo Injection as the Therapy for Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial update for KXV01 TCR Lentinvivo injection in advanced solid tumors; the study is not yet recruiting.