Solid Tumor
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Follow-Up Evaluation for Gene-Therapy-Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical Trials
An update on follow-up evaluation for gene-therapy–related delayed adverse events in participants of pediatric oncology branch trials; the s…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Clinical Study of HX111 in Patients With Advanced Solid Tumor and Lymphoma [Phase 1, Phase 2]
This clinical trial update describes HX111 testing in patients with advanced solid tumors and lymphoma, currently in Phase 1/2 and not yet r…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation [Phase 1]
The update covers an ongoing Phase 1 basket trial evaluating Neratinib plus Everolimus, Palbociclib, or Trametinib in patients with refracto…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ASD141 [Phase 1]
Phase 1 trial evaluating ASD141 for safety, tolerability, pharmacokinetics, and preliminary efficacy in metastatic solid tumors; recruitment…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: A Study of Lutetium [177Lu] BL-ARC001 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumors and Other Solid Tumors [Phase 1]
A Phase 1 trial evaluating Lutetium-177Lu BL-ARC001 in locally advanced or metastatic gastrointestinal cancers and other solid tumors is cur…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Clinical Trial of the Safety and Efficacy of IBA Proton Therapy System PROTEUS® PLUS (Sichuan) [NA]
This clinical trial update reports on the safety and efficacy evaluation of the PROTEUS® PLUS Proton Therapy System by Ion Beam Applications…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: Study of ZGGS18 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Clinical trial update for ZGGS18 in patients with advanced solid tumors (Phase 1/Phase 2) currently recruiting.
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: A Study of Recombinant Oncolytic Virus M1(VRT106) in Patients With Solid Tumors [Phase 1]
This clinical trial update describes an ongoing Phase 1 study evaluating the recombinant oncolytic virus M1 (VRT106) in patients with solid …
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: A Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors [Phase 1]
ClinicalTrials.gov entry notes a Phase 1 study of XB628 in participants with recurrent advanced or metastatic solid tumors, currently recrui…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-tumor Activity of ASKC202 With or Without ASK120067 [Phase 1]
Phase 1 clinical trial to assess safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of ASKC202 with or without ASK12…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Ex Vivo Expansion (ACT-X)
Mayo Clinic's ACT-X ex vivo expansion therapy is in a recruiting clinical trial for solid tumors. Enrollment is currently ongoing.
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: A Study of SHR-4375 Injection in Combination With Other Antitumor Therapies in Patients With Solid Tumors [Phase 1, Phase 2]
Clinical trial update for SHR-4375 Injection in combination with other antitumor therapies in patients with advanced solid tumors. The study…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Study of RP-3500 in Combination With Standard Radiation Therapy in People With Solid Tumor Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating RP-3500 in combination with standard radiation therapy for solid tumors, including metastatic cancer, …
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors [Phase 1]
A Phase 1 clinical trial update for JZP898 as monotherapy and in combination with pembrolizumab in adults with advanced or metastatic solid …
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: TCR-engineered T Cells (NW-101C) in Patients With Solid Malignant Tumors [Phase 1]
Phase 1 clinical trial update for NW-101C, a TCR-engineered T cell therapy by Neowise Biotechnology, targeting metastatic solid tumors; recr…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: A Study of GC203 TIL in Advanced Malignant Solid Tumors [Phase 1]
This Phase 1 study of GC203 TIL in advanced malignant solid tumors is currently recruiting across multiple cancer types, including gynecolog…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment [Phase 1, Phase 2]
Clinical trial update for neratinib in children and young adults with cancer, focusing on safety and dose finding in Phase 1/Phase 2.
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors [Phase 2]
A Phase 2 clinical trial evaluating selinexor in Wilms tumor, rhabdoid tumors, and other solid tumors is currently recruiting at Memorial Sl…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol [Phase 2, Phase 3]
The DETERMINE master screening protocol is a platform trial designed to determine extended therapeutic indications for existing drugs in rar…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers [Phase 2, Phase 3]
The DETERMINE trial treatment arm 01 is evaluating Alectinib in adult, paediatric and teenage/young adult patients with ALK-positive cancers…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Safety and Tolerability of a mRNA Vaccine Encoding Tumor-Specific Circular RNA Antigens in Combination With Anti-PD-1 Monoclonal Antibody in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Clinical trial update on the safety and tolerability of an mRNA vaccine encoding tumor-specific circular RNA antigens in combination with an…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Expressive Writing for the Management of Stress in Cancer Survivors [NA]
The study 'Expressive Writing for the Management of Stress in Cancer Survivors' is currently recruiting, sponsored by MD Anderson Cancer Cen…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating LAM561 Acid in pediatric patients with malignant glioma and other advanced solid tumors is currently r…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: SB17170 Phase 1 Clinical Trial in Solid Tumors [Phase 1]
This clinical trial update notes that SB17170 is in a Phase 1 study for solid tumors and is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: A Study of MHB036C for Advanced Solid Tumor [Phase 1, Phase 2]
This update describes a Phase 1/Phase 2 study of the experimental cancer therapy MHB036C for advanced solid tumors, with the trial currently…