Small Lymphocytic Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
This clinical trial update notes a Phase 2 study of acalabrutinib with or without obinutuzumab in patients with early-stage chronic lymphocy…
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CLINICAL_TRIALS trial_result · 2026-02-02Clinical Trial Update: Testing the Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia [Phase 3]
A Phase 3 trial is evaluating whether adding venetoclax to the standard combination of ibrutinib and obinutuzumab improves outcomes in untre…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL) [Phase 1]
Phase 1 dose-escalation and dose-expansion study to evaluate the safety of Azer-cel (PBCAR0191) in relapsed/refractory non-Hodgkin lymphoma …
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) [Phase 3]
Phase 3 trial comparing Pirtobrutinib plus Venetoclax and Rituximab (PVR) versus Venetoclax and Rituximab (VR) in previously treated chronic…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Assessing Minimal Residual Disease by Next- Generation Sequencing to Minimize Exposure in People With CLL or SLL Who Have Been Treated With Venetoclax [Phase 2]
Phase 2 clinical trial evaluating minimal residual disease assessment by next-generation sequencing to minimize exposure in patients with ch…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy [Phase 3]
Phase 3 clinical trial evaluating a digital health intervention for self-management and telemonitoring in CAR-T therapy is currently recruit…
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CLINICAL_TRIALS trial_result · 2026-01-27Clinical Trial Update: A Study of Oral LOXO-305 in Patients With Previously Treated CLL/SLL or NHL [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial of the oral BTK inhibitor LOXO-305 (pirtobrutinib) in patients with previously treated chronic lymphocy…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Combination of Lenalidomide and Rituximab in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL-SLL) [Phase 2]
A Phase 2 trial evaluating the combination of lenalidomide and rituximab in chronic lymphocytic leukemia/small lymphocytic lymphoma is curre…
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies [Phase 1]
A Phase 1 clinical trial evaluates PRT2527 as a standalone therapy and in combination with zanubrutinib or venetoclax for relapsed/refractor…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: A Study of Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated Patients With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) [Phase 3]
A Phase 3 clinical trial comparing pirtobrutinib to bendamustine plus rituximab in untreated chronic lymphocytic leukemia/small lymphocytic …
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab [Phase 2]
Phase 2 study evaluating disease risk mutation-guided finite acalabrutinib plus venetoclax for relapsed chronic lymphocytic leukemia and sma…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Fixed Duration Pirtobrutinib and Obinutuzumab in Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial investigating a fixed-duration regimen of pirtobrutinib plus obinutuzumab in chronic lymphocytic leukemia or small lymphocyt…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma. [Phase 1]
Phase 1 study evaluating T cells engineered to co-express kappa and CD28 CARs for relapsed/refractory kappa+ non-Hodgkin lymphoma and chroni…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: ROCKET-CLL Global Phase 3 Study: Rocbrutinib vs Pirtobrutinib in cBTKi-Pretreated R/R CLL/SLL [Phase 3]
A Phase 3 global trial (ROCKET-CLL) comparing rocbrutinib to pirtobrutinib in patients previously treated with covalent BTK inhibitors and w…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma [Phase 1]
This is a Phase 1 trial evaluating anti-CD19 CAR-T cell therapy for relapsed or refractory non-Hodgkin lymphoma. The study is currently recr…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: A Study Assessing Adverse Event and How Oral ABBV-453 Moves Through the Body in Adult Participants With Relapsed or Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) [Phase 1]
Phase 1 trial update of ABBV-453 in relapsed/refractory chronic lymphocytic leukemia and small lymphocytic lymphoma, focusing on adverse eve…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Anti-pneumococcal Vaccine Strategy in Patients With Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating an anti-pneumococcal vaccine strategy in patients with Chronic Lymphocytic Leukemia and Small lymphocyti…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Safe Accelerated Venetoclax Escalation in CLL [Phase 1]
Phase 1 trial update reporting safe accelerated venetoclax escalation in chronic lymphocytic leukemia and small lymphocytic lymphoma.
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Intermittent Versus Continuous Venetoclax With Acalabrutinib for CLL/SLL [Phase 2]
Phase 2 trial evaluating intermittent versus continuous venetoclax in combination with acalabrutinib for chronic lymphocytic leukemia and sm…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: REtreatment With VEnetoclax and Acalabrutinib After Venetoclax Limited Duration (REVEAL) [Phase 2]
Phase 2 trial REVEAL evaluates retreatment with venetoclax plus acalabrutinib after a limited duration of venetoclax in patients with CLL/SL…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Study of Epcoritamab as a Consolidation Therapy in CLL/SLL [Phase 2]
Phase 2 study evaluating epcoritamab as consolidation therapy for chronic lymphocytic leukemia/small lymphocytic lymphoma is currently recru…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: LEF1 EXPRESSION IN B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS: A MARKER FOR DIAGNOSIS AND SURVIVAL PREDICTION
This clinical trial is currently recruiting to evaluate LEF1 expression in B-cell chronic lymphocytic leukemia and small lymphocytic lymphom…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia [Phase 2]
A phase 2 clinical trial evaluating the combination of acalabrutinib and obinutuzumab for Chronic Lymphocytic Leukemia and Small Lymphocytic…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Study of Autologous Peripheral Blood Lymphocytes in the Treatment of Patients With CLL or SLL [Phase 1]
Clinical trial update for a Phase 1 study evaluating autologous peripheral blood lymphocytes in chronic lymphocytic leukemia and small lymph…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Study of DZD8586 Combination in CLL/SLL (TAI-SHAN10) [Phase 2]
This clinical trial update notes that a Phase 2 study of DZD8586 in combination therapy for chronic lymphocytic leukemia and small lymphocyt…