Small Lymphocytic Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Long-term Extension Study of PCI-32765 (Ibrutinib) [Phase 3]
Phase 3 long-term extension study of ibrutinib (PCI-32765) in chronic lymphocytic leukemia/small lymphocytic lymphoma and other B-cell malig…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Study of NX-5948 in Combination With Other Agents in Adults With B-cell Malignancies [Phase 1, Phase 2]
This document provides an update on a Phase 1/2 study of NX-5948 in combination with other agents for adults with B-cell malignancies. The t…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial is evaluating the effectiveness of Mirdametinib in relapsed/refractory chronic lymphocytic leukemia and small lymph…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011) [Phase 3]
Phase 3 trial evaluating Nemtabrutinib (MK-1026) versus investigator's choice of ibrutinib or acalabrutinib in first-line chronic lymphocyti…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Pneumococcal Pneumonia Vaccine Series (PCV20 and PPSV23) in Patients With Chronic Lymphocytic Leukemia Associated Immunodeficiency, PROTECT CLL Trial [Phase 2]
The PROTECT CLL trial is a Phase 2 study evaluating vaccination with PCV20 and PPSV23 in patients with CLL-associated immunodeficiency; the …
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients [NA]
This study examines how structured exercise affects immune phenotype in patients with indolent non-Hodgkin lymphoma and chronic lymphocytic …
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma [Phase 1, Phase 2]
Genmab-sponsored first-in-human trial in relapsed/refractory B-cell lymphomas spans Phase 1/2 and is currently active/not recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: Long-term Follow-up Study for Patients Treated With CLBR001 CAR-T [Phase 1]
This clinical trial update reports long-term follow-up results from a Phase 1 study of CLBR001 CAR-T cells in relapsed/refractory B-cell lym…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (R/R B-NHL) [Phase 1, Phase 2]
Clinical trial update announcing a Phase 1/2 study of epcoritamab in Japanese patients with relapsed or refractory B-cell non-Hodgkin lympho…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL [Phase 3]
A Phase 3 clinical trial is planned to compare NX-5948 against Pirtobrutinib in relapsed/refractory chronic lymphocytic leukemia and small l…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Ibrutinib as an Immune Modulating Agent for Patients With Asymptomatic, High-risk CLL/SLL Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 trial update evaluating ibrutinib as an immune-modulating agent for asymptomatic, high-risk chronic lymphocytic leukemia or small ly…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study on Limiting Treatment Time With Acalabrutinib Combined With Obinutuzumab in People With CLL or SLL [Phase 2]
This update covers a Phase 2 trial evaluating shortening treatment duration with acalabrutinib in combination with obinutuzumab for chronic …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV) [Phase 3]
This clinical trial update describes Surovatamig as consolidation therapy for chronic lymphocytic leukemia or small lymphocytic lymphoma wit…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Predictors of Health-Related QOL in Adults With CLL or Small Lymphocytic Lymphoma
A recruiting study evaluating predictors of health-related quality of life in adults with chronic lymphocytic leukemia or small lymphocytic …
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19) [Phase 1, Phase 2]
A Phase 1/2 clinical trial of SENTRY-CD19, a CD19-targeted gene therapy, in multiple CD19-positive hematologic malignancies is currently rec…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study of DZD8586 Versus Investigator's Choice in r/r CLL/SLL (TAI-SHAN6) [Phase 3]
This clinical trial update notes a Phase 3 study evaluating DZD8586 versus investigator's choice in relapsed/refractory chronic lymphocytic …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study of APG-2575 in Patients With Relapsed/Refractory CLL/SLL [Phase 2]
Phase 2 clinical trial update for APG-2575 in relapsed/refractory chronic lymphocytic leukemia and small lymphocytic lymphoma; the study is …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies [Phase 1]
Phase 1 clinical trial evaluating Sonrotoclax (BGB-11417), a Bcl-2 inhibitor, in participants with mature B-cell malignancies. The study is …
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Acalabrutinib, Venetoclax and Durvalumab for the Treatment of Richter Transformation From Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
A Phase 2 clinical trial evaluating a three-drug combination (acalabrutinib, venetoclax, and durvalumab) for Richter transformation arising …
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CLINICAL_TRIALS trial_result · 2026-03-24Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma [Phase 2]
A Phase 2 clinical trial evaluating pirtobrutinib for relapsed or refractory chronic lymphocytic leukemia and small lymphocytic lymphoma is …
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CLINICAL_TRIALS trial_result · 2026-03-23Clinical Trial Update: Duvelisib and Venetoclax in Relapsed or Refractory CLL or SLL or RS [Phase 1, Phase 2]
Clinical trial update on the Phase 1/2 study of the duvelisib and venetoclax combination in relapsed or refractory Chronic Lymphocytic Leuke…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies [Phase 1]
Phase 1 study evaluating NX-2127 in adults with relapsed or refractory B-cell malignancies; currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-20Clinical Trial Update: Zanubrutinib and Rituximab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
A Phase 2 trial evaluating the combination of zanubrutinib and rituximab for previously untreated chronic lymphocytic leukemia or small lymp…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Study of Iopofosine I-131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) With Expansion in Waldenstrom [Phase 2]
Phase 2 clinical trial update for CLR-131 in select B-cell malignancies, with expansion into Waldenström macroglobulinemia. The study status…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: A Study of Voruciclib Alone or in Combination With Venetoclax in Subjects With B-Cell Malignancies or AML [Phase 1]
Phase 1 trial update for voruciclib alone or with venetoclax in various B-cell malignancies and acute myeloid leukemia; the study has been t…