Small Lymphocytic Lymphoma

• CLINICAL_TRIALS trial_result · 2020-03-03
  Clinical Trial Update: A Study of Ibrutinib in Combination With Bendamustine and Rituximab in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 3]

  Phase 3 trial evaluating ibrutinib with bendamustine and rituximab in relapsed/refractory CLL or SLL has completed with results posted.

• CLINICAL_TRIALS trial_result · 2020-02-24
  Clinical Trial Update: Pilot Study to Determine Effects of the Btk Inhibitor PCI-32765 on Leukemia Cell Kinetics and Trafficking, Using Heavy Water Labeling in Subjects With CLL and SLL [Phase 1, Phase 2]

  A pilot study evaluating the Btk inhibitor PCI-32765 (ibrutinib) effects on leukemia cell kinetics and trafficking in CLL/SLL using heavy wa…

• CLINICAL_TRIALS trial_result · 2020-01-30
  Clinical Trial Update: Study to Evaluate Safety and Preliminary Efficacy of Tafasitamab With Idelalisib or Venetoclax in R/R CLL/SLL Patients Pretreated With BTKi [Phase 2]

  Phase 2 study evaluating safety and preliminary efficacy of tafasitamab with idelalisib or venetoclax in relapsed/refractory CLL/SLL patient…

• CLINICAL_TRIALS trial_result · 2019-11-22
  Clinical Trial Update: Donor Atorvastatin Treatment in Preventing Severe Acute GVHD After Nonmyeloablative Peripheral Blood Stem Cell Transplant in Patients With Hematological Malignancies [Phase 2]

  Phase 2 clinical trial assessing donor atorvastatin to prevent severe acute GVHD after nonmyeloablative peripheral blood stem cell transplan…

• CLINICAL_TRIALS trial_result · 2019-10-22
  Clinical Trial Update: Bortezomib, Cladribine, and Rituximab in Treating Patients With Advanced Mantle Cell Lymphoma or Indolent Lymphoma [Phase 2]

  Phase 2 clinical trial of bortezomib, cladribine, and rituximab in advanced mantle cell lymphoma or indolent lymphoma has completed with res…

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• CLINICAL_TRIALS trial_result · 2019-10-11
  Clinical Trial Update: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer [Phase 2]

  Phase 2 clinical trial update on donor umbilical cord blood transplant for hematologic cancers; status completed with results posted.

• CLINICAL_TRIALS trial_result · 2019-09-19
  Clinical Trial Update: Dimethylfumarate (DMF) in Relapsed/Refractory CLL/SLL [Phase 1]

  Phase 1 trial evaluating dimethylfumarate in relapsed/refractory chronic lymphocytic leukemia and small lymphocytic lymphoma; study terminat…

• CLINICAL_TRIALS trial_result · 2019-09-18
  Clinical Trial Update: Phase 2 Study of the Combination of Bruton's Tyrosine Kinase Inhibitor PCI-32765 and Rituximab in High-Risk Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma Patients [Phase 2]

  Phase 2 trial evaluating the combination of PCI-32765 (ibrutinib) and rituximab in high-risk chronic lymphocytic leukemia and small lymphocy…

• CLINICAL_TRIALS trial_result · 2019-09-17
  Clinical Trial Update: Ofatumumab-based Induction Chemoimmunotherapy in Previously Untreated Patients With CLL/SLL [Phase 2]

  Phase 2 trial evaluating ofatumumab-based induction chemoimmunotherapy in previously untreated chronic lymphocytic leukemia/small lymphocyti…

• CLINICAL_TRIALS trial_result · 2019-09-06
  Clinical Trial Update: Sapacitabine, Cyclophosphamide, Rituximab for Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma (CLL/SLL) With Deletion (11q22-23) [Phase 2]

  Phase 2 trial investigating sapacitabine with cyclophosphamide and rituximab for relapsed CLL/SLL with 11q deletion; study terminated with r…

• CLINICAL_TRIALS trial_result · 2019-07-11
  Clinical Trial Update: Fludarabine Phosphate, Radiation Therapy, and Rituximab in Treating Patients Who Are Undergoing Donor Stem Cell Transplant Followed by Rituximab for High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]

  Phase 2 clinical trial evaluating fludarabine phosphate, radiation therapy, and rituximab followed by rituximab maintenance in high-risk chr…

• CLINICAL_TRIALS trial_result · 2019-06-26
  Clinical Trial Update: Ofatumumab With High Dose Methylprednisone Followed by Ofatumumab and Alemtuzumab in 17p CLL [Phase 2]

  A phase 2 trial evaluating high-dose methylprednisone followed by ofatumumab and alemtuzumab in 17p deletion CLL/SLL has been terminated wit…

• CLINICAL_TRIALS trial_result · 2019-05-29
  Clinical Trial Update: Autologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia [Phase 2]

  Phase 2 clinical trial evaluating autologous peripheral blood stem cell transplant followed by donor bone marrow transplant in high-risk B- …

• CLINICAL_TRIALS trial_result · 2019-05-21
  Clinical Trial Update: PCI-32765 (Ibrutinib) in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or B-cell Prolymphocytic Leukemia [Phase 2]

  Phase 2 results for Ibrutinib (PCI-32765) in relapsed or refractory chronic lymphocytic leukemia, small lymphocytic lymphoma, and B-cell pro…

• CLINICAL_TRIALS trial_result · 2019-05-07
  Clinical Trial Update: Lenalidomide and Ofatumumab in Treating Participants With Previously Treated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]

  Phase 2 trial evaluating lenalidomide plus ofatumumab in previously treated chronic lymphocytic leukemia or small lymphocytic lymphoma; comp…

• CLINICAL_TRIALS trial_result · 2019-04-16
  Clinical Trial Update: A Multi-Center Study of Ibrutinib in Combination With Obinutuzumab Versus Chlorambucil in Combination With Obinutuzumab in Patients With Treatment naïve Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) [Phase 3]

  Phase 3 trial comparing ibrutinib+obinutuzumab vs chlorambucil+obinutuzumab in treatment-naïve CLL/SLL; study completed with results posted …

• CLINICAL_TRIALS trial_result · 2019-02-26
  Clinical Trial Update: Dose Optimization Trial of CD19 Redirected Autologous T Cells [Phase 2]

  Phase 2 dose optimization trial of CD19 redirected autologous T cells in adults with relapsed/refractory CLL or SLL has completed with poste…

• CLINICAL_TRIALS trial_result · 2019-01-23
  Clinical Trial Update: Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203) [Phase 2]

  Phase 2 study evaluating novel approaches to prevent graft-versus-host disease after allogeneic hematopoietic cell transplantation, with res…

• CLINICAL_TRIALS trial_result · 2019-01-08
  Clinical Trial Update: A Phase 3 Study of Duvelisib Versus Ofatumumab in Patients With Relapsed or Refractory CLL/SLL (DUO) [Phase 3]

  Phase 3 trial comparing duvelisib to ofatumumab in relapsed/refractory CLL/SLL has completed with results posted.

• CLINICAL_TRIALS trial_result · 2018-09-18
  Clinical Trial Update: Ofatumumab, Pentostatin, and Cyclophosphamide in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]

  Phase 2 trial investigating ofatumumab, pentostatin, and cyclophosphamide for untreated chronic lymphocytic leukemia or small lymphocytic ly…

• CLINICAL_TRIALS trial_result · 2018-07-11
  Clinical Trial Update: PCI-32765 for Special Cases of Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]

  Phase 2 clinical trial update of the BTK inhibitor Ibrutinib (PCI-32765) in special cases of chronic lymphocytic leukemia and small lymphocy…

• CLINICAL_TRIALS trial_result · 2018-07-02
  Clinical Trial Update: CPI-613, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma [Phase 1]

  Phase 1 trial evaluating a triple regimen of devimistat (CPI-613), bendamustine hydrochloride, and rituximab in relapsed or refractory B-cel…

• CLINICAL_TRIALS trial_result · 2018-04-23
  Clinical Trial Update: Bortezomib and Romidepsin in Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma [Phase 1]

  Phase 1 study evaluating the combination of bortezomib and romidepsin in patients with chronic lymphocytic leukemia or small lymphocytic lym…

• CLINICAL_TRIALS trial_result · 2018-04-12
  Clinical Trial Update: Efficacy and Safety of Ibrutinib in Patients With CLL and Other Indolent B-cell Lymphomas Who Are Chronic Hepatitis B Virus Carriers or Occult Hepatitis B Virus Carriers [Phase 3]

  Phase 3 trial update on the efficacy and safety of ibrutinib in patients with chronic lymphocytic leukemia and indolent B-cell lymphomas who…

• CLINICAL_TRIALS trial_result · 2018-03-30
  Clinical Trial Update: BR in Patients With CLL With Comorbidities and/or Renal Dysfunction [Phase 1]

  A Phase 1 clinical trial evaluating the bendamustine-rituximab (BR) regimen in patients with chronic lymphocytic leukemia or small lymphocyt…