Small Lymphocytic Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Acalabrutinib for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma [Phase 2]
Phase 2 clinical trial evaluating acalabrutinib for chronic lymphocytic leukemia and small lymphocytic lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Mosunetuzumab for CLL MRD Clearance [Phase 1, Phase 2]
Clinical trial update for mosunetuzumab in chronic lymphocytic leukemia focusing on measurable residual disease clearance in Phase 1/2 studi…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma [Phase 1]
An ongoing Phase 1 clinical trial update for AS-1763 in adults with previously treated B-cell malignancies, including chronic lymphocytic le…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Zanubrutinib and Venetoclax in CLL (ZANU-VEN) [Phase 2]
A Phase 2 clinical trial (ZANU-VEN) evaluating the combination of zanubrutinib and venetoclax for chronic lymphocytic leukemia and small lym…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Innovative Biomarkers of Cardiovascular Complications Associated With Second-generation Bruton Tyrosine Kinase Inhibitor Treatments: a Single-center Cohort Study
A single-center cohort study is assessing biomarkers of cardiovascular complications in patients treated with second-generation BTK inhibito…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: French Observational Study of Patients With Chronic Lymphocytic Leukemia Or Small Lymphocytic Lymphoma in Real-World Settings
A French observational study of patients with chronic lymphocytic leukemia or small lymphocytic lymphoma in real-world settings is ongoing b…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: DZD8586 in Patients With Relapsed or Refractory CLL/SLL (TAI-SHAN8) [Phase 2]
A Phase 2 clinical trial evaluating DZD8586 in patients with relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma …
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Venetoclax as Consolidation in CLL Patients Treated With BTK Inhibitor Monotherapy [Phase 2]
A Phase 2 trial is evaluating venetoclax as consolidation therapy in chronic lymphocytic leukemia or small lymphocytic lymphoma patients on …
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Watch and Wait or Worry and Wait in Indolent Lymphoma
An ongoing clinical trial at Seoul National University Hospital is evaluating watchful waiting versus proactive worry-and-wait strategies in…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: ICP-248 in Combination With Orelabrutinib in Treatment-naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (APEX-03) [Phase 2, Phase 3]
APEX-03 is a Phase 2/3 clinical trial evaluating ICP-248 in combination with orelabrutinib for treatment-naïve chronic lymphocytic leukemia …
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Acalabrutinib in Combination With Venetoclax for the Treatment of Refractory or Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, The AVENUE-2 Trial [Phase 2]
The AVENUE-2 Phase 2 trial investigates acalabrutinib in combination with venetoclax for patients with refractory or recurrent chronic lymph…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating CTX112 in relapsed or refractory B-cell malignancies is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Long-term Follow-up Study of Patients Receiving CAR-T Cells
This clinical trial update outlines a long-term follow-up study of patients who received CAR-T cell therapy. Sponsored by the Medical Colleg…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Ibrutinib With or Without Rituximab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial is evaluating ibrutinib with or without rituximab in patients with relapsed chronic lymphocytic leukemia and related lymphop…
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CLINICAL_TRIALS research · 2025-11-06Clinical Trial Update: Tafasitamab, Acalabrutinib, and Obinutuzumab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma [Phase 1]
Phase 1 clinical trial evaluating a triplet regimen of tafasitamab, acalabrutinib, and obinutuzumab for previously untreated chronic lymphoc…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Tafasitamab and Zanubrutinib for the Treatment of Patients With Newly Diagnosed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, TaZA CLL Study [Phase 2]
Phase 2 TaZA CLL study evaluating the combination of tafasitamab and zanubrutinib for newly diagnosed chronic lymphocytic leukemia or small …
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial [Phase 3]
Phase 3 PIRAMID trial evaluating adding pirtobrutinib to standard therapy for newly diagnosed Richter transformation (transformed CLL/SLL to…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) [Phase 2]
A Phase II randomized trial evaluating a Bruton tyrosine kinase inhibitor with or without venetoclax in veterans with chronic lymphocytic le…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: A Phase Ib Study of the Selective PKC-β Inhibitor MS-553 in Patients With Refractory or Relapsed CLL/SLL [Phase 1, Phase 2]
A Phase Ib study of the selective PKC-β inhibitor MS-553 in patients with refractory or relapsed chronic lymphocytic leukemia or small lymph…
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Zanubrutinib, Obinutuzumab, and Sonrotoclax in Previously Untreated Patients With CLL or SLL [Phase 2]
Phase 2 trial evaluating a combination of zanubrutinib, obinutuzumab, and sonrotoclax in previously untreated chronic lymphocytic leukemia a…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Immunotherapy for High Risk/Relapsed CD19+ Acute Lymphoblastic Leukaemia, B-cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)/ Small Lymphocytic Lymphoma (SLL) Using CAR T-cells to Target CD19 [Phase 1]
A Phase 1 clinical trial update describing CD19-targeted CAR T-cell immunotherapy for high-risk or relapsed CD19+ acute lymphoblastic leukem…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Global Trial in APG2575 for Patients With CLL/SLL [Phase 3]
Global Phase 3 trial of APG2575 in chronic lymphocytic leukemia and small lymphocytic lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: GT719 Injection for the Treatment of Recurrent/Refractory CD19 Positive Adult B-cell Malignancies [Phase 1, Phase 2]
GT719 Injection is being studied in a Phase 1/2 trial for recurrent or refractory CD19-positive adult B-cell malignancies, with recruitment …
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment
This clinical trial update describes a study assessing vaccine responses in patients who previously received CAR-T therapy for multiple myel…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: CD19.20.22 CAR T-cells for Patients With Relapsed/Refractory B-Cell Lymphomas [Phase 1]
This entry provides an update on an ongoing Phase 1 trial of CD19-targeted CAR T-cells (CD19.20.22) for relapsed/refractory B-cell lymphomas…