Small Lymphocytic Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias [Phase 1, Phase 2]
Clinical trial update on an anti-CD19 CAR-T cell therapy being evaluated in Phase 1/Phase 2 for various leukemias and lymphoid cancers; recr…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Pirtobrutinib (LOXO-305) and Venetoclax for the Treatment of Patients With CLL or SLL Resistant to Covalent BTKi [Phase 2]
This clinical trial update describes a Phase 2 study evaluating pirtobrutinib in combination with venetoclax for patients with chronic lymph…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Acalabrutinib in Combination With Venetoclax or Obinutuzumab for the Treatment of Treatment-naive Chronic Lymphocytic Leukemia [Phase 2]
This is a Phase 2 clinical trial update on acalabrutinib combined with venetoclax or obinutuzumab for treatment-naive chronic lymphocytic le…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 3]
A Phase 3 clinical trial comparing acalabrutinib plus venetoclax versus venetoclax plus obinutuzumab in previously untreated chronic lymphoc…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies. [Phase 1]
A Phase 1 clinical trial evaluating oral LP-168 in relapsed or refractory B-cell malignancies is recruiting. Target conditions include CLL/S…
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies [Phase 1]
Phase 1 clinical trial from Mayo Clinic is evaluating BAFFR-based CAR-T cells with lymphodepletion (fludarabine and cyclophosphamide) for re…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Pirtobrutinib and Venetoclax With MRD Detection for Previously Untreated Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 clinical trial update examining the combination of pirtobrutinib and venetoclax with measurable residual disease (MRD) detection for…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
This clinical trial update notes a Phase 2 study of acalabrutinib with or without obinutuzumab in patients with early-stage chronic lymphocy…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL) [Phase 1]
Phase 1 dose-escalation and dose-expansion study to evaluate the safety of Azer-cel (PBCAR0191) in relapsed/refractory non-Hodgkin lymphoma …
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) [Phase 3]
Phase 3 trial comparing Pirtobrutinib plus Venetoclax and Rituximab (PVR) versus Venetoclax and Rituximab (VR) in previously treated chronic…
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CLINICAL_TRIALS research · 2026-01-29Clinical Trial Update: Assessing Minimal Residual Disease by Next- Generation Sequencing to Minimize Exposure in People With CLL or SLL Who Have Been Treated With Venetoclax [Phase 2]
Phase 2 clinical trial evaluating minimal residual disease assessment by next-generation sequencing to minimize exposure in patients with ch…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy [Phase 3]
Phase 3 clinical trial evaluating a digital health intervention for self-management and telemonitoring in CAR-T therapy is currently recruit…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Combination of Lenalidomide and Rituximab in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL-SLL) [Phase 2]
A Phase 2 trial evaluating the combination of lenalidomide and rituximab in chronic lymphocytic leukemia/small lymphocytic lymphoma is curre…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: A Study of Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated Patients With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) [Phase 3]
A Phase 3 clinical trial comparing pirtobrutinib to bendamustine plus rituximab in untreated chronic lymphocytic leukemia/small lymphocytic …
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Fixed Duration Pirtobrutinib and Obinutuzumab in Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial investigating a fixed-duration regimen of pirtobrutinib plus obinutuzumab in chronic lymphocytic leukemia or small lymphocyt…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Study of Kappa Chimeric Antigen Receptor (CAR) T Lymphocytes Co-Expressing the Kappa and CD28 CARs for Relapsed/Refractory Kappa+ Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma. [Phase 1]
Phase 1 study evaluating T cells engineered to co-express kappa and CD28 CARs for relapsed/refractory kappa+ non-Hodgkin lymphoma and chroni…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Anti-CD19 Chimeric Antigen Receptor T Cells for Treatment of Relapsed or Refractory Non-Hodgkin Lymphoma [Phase 1]
This is a Phase 1 trial evaluating anti-CD19 CAR-T cell therapy for relapsed or refractory non-Hodgkin lymphoma. The study is currently recr…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Safe Accelerated Venetoclax Escalation in CLL [Phase 1]
Phase 1 trial update reporting safe accelerated venetoclax escalation in chronic lymphocytic leukemia and small lymphocytic lymphoma.
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Intermittent Versus Continuous Venetoclax With Acalabrutinib for CLL/SLL [Phase 2]
Phase 2 trial evaluating intermittent versus continuous venetoclax in combination with acalabrutinib for chronic lymphocytic leukemia and sm…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: REtreatment With VEnetoclax and Acalabrutinib After Venetoclax Limited Duration (REVEAL) [Phase 2]
Phase 2 trial REVEAL evaluates retreatment with venetoclax plus acalabrutinib after a limited duration of venetoclax in patients with CLL/SL…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Study of Epcoritamab as a Consolidation Therapy in CLL/SLL [Phase 2]
Phase 2 study evaluating epcoritamab as consolidation therapy for chronic lymphocytic leukemia/small lymphocytic lymphoma is currently recru…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: LEF1 EXPRESSION IN B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA PATIENTS: A MARKER FOR DIAGNOSIS AND SURVIVAL PREDICTION
This clinical trial is currently recruiting to evaluate LEF1 expression in B-cell chronic lymphocytic leukemia and small lymphocytic lymphom…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia [Phase 2]
A phase 2 clinical trial evaluating the combination of acalabrutinib and obinutuzumab for Chronic Lymphocytic Leukemia and Small Lymphocytic…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Study of DZD8586 Combination in CLL/SLL (TAI-SHAN10) [Phase 2]
This clinical trial update notes that a Phase 2 study of DZD8586 in combination therapy for chronic lymphocytic leukemia and small lymphocyt…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma [Phase 2]
Phase 2 clinical trial evaluating venetoclax in relapsed or refractory chronic lymphocytic leukemia and small lymphocytic lymphoma is curren…