Small Lymphocytic Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Pneumococcal Pneumonia Vaccine Series (PCV20 and PPSV23) in Patients With Chronic Lymphocytic Leukemia Associated Immunodeficiency, PROTECT CLL Trial [Phase 2]
The PROTECT CLL trial is a Phase 2 study evaluating vaccination with PCV20 and PPSV23 in patients with CLL-associated immunodeficiency; the …
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients [NA]
This study examines how structured exercise affects immune phenotype in patients with indolent non-Hodgkin lymphoma and chronic lymphocytic …
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma [Phase 1, Phase 2]
Genmab-sponsored first-in-human trial in relapsed/refractory B-cell lymphomas spans Phase 1/2 and is currently active/not recruiting.
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (R/R B-NHL) [Phase 1, Phase 2]
Clinical trial update announcing a Phase 1/2 study of epcoritamab in Japanese patients with relapsed or refractory B-cell non-Hodgkin lympho…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL [Phase 3]
A Phase 3 clinical trial is planned to compare NX-5948 against Pirtobrutinib in relapsed/refractory chronic lymphocytic leukemia and small l…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study on Limiting Treatment Time With Acalabrutinib Combined With Obinutuzumab in People With CLL or SLL [Phase 2]
This update covers a Phase 2 trial evaluating shortening treatment duration with acalabrutinib in combination with obinutuzumab for chronic …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV) [Phase 3]
This clinical trial update describes Surovatamig as consolidation therapy for chronic lymphocytic leukemia or small lymphocytic lymphoma wit…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Predictors of Health-Related QOL in Adults With CLL or Small Lymphocytic Lymphoma
A recruiting study evaluating predictors of health-related quality of life in adults with chronic lymphocytic leukemia or small lymphocytic …
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19) [Phase 1, Phase 2]
A Phase 1/2 clinical trial of SENTRY-CD19, a CD19-targeted gene therapy, in multiple CD19-positive hematologic malignancies is currently rec…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study of DZD8586 Versus Investigator's Choice in r/r CLL/SLL (TAI-SHAN6) [Phase 3]
This clinical trial update notes a Phase 3 study evaluating DZD8586 versus investigator's choice in relapsed/refractory chronic lymphocytic …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study of APG-2575 in Patients With Relapsed/Refractory CLL/SLL [Phase 2]
Phase 2 clinical trial update for APG-2575 in relapsed/refractory chronic lymphocytic leukemia and small lymphocytic lymphoma; the study is …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Study of Bcl-2 Inhibitor Sonrotoclax (BGB-11417) in Participants With Mature B-Cell Malignancies [Phase 1]
Phase 1 clinical trial evaluating Sonrotoclax (BGB-11417), a Bcl-2 inhibitor, in participants with mature B-cell malignancies. The study is …
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Acalabrutinib, Venetoclax and Durvalumab for the Treatment of Richter Transformation From Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
A Phase 2 clinical trial evaluating a three-drug combination (acalabrutinib, venetoclax, and durvalumab) for Richter transformation arising …
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies [Phase 1]
Phase 1 study evaluating NX-2127 in adults with relapsed or refractory B-cell malignancies; currently recruiting.
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Study of Iopofosine I-131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) With Expansion in Waldenstrom [Phase 2]
Phase 2 clinical trial update for CLR-131 in select B-cell malignancies, with expansion into Waldenström macroglobulinemia. The study status…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study to Evaluate MTM-H-001 Injection in Adult Participants With Relapsed or Refractory B-cell Malignancies [NA]
This clinical trial update describes an evaluation of MTM-H-001 injection in adults with relapsed or refractory B-cell lymphomas, with the s…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: A Study of Nemtabrutinib vs Chemoimmunotherapy for Participants With Previously Untreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) Without TP53 Aberrations (MK-1026-008, BELLWAVE-008) [Phase 3]
Phase 3 study MK-1026-008/BELLWAVE-008 is evaluating nemtabrutinib against chemoimmunotherapy in previously untreated chronic lymphocytic le…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Venetoclax and Obinutuzumab Followed by Epcoritamab for the Treatment of Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, LonGEVity Trial [Phase 2]
Phase 2 LonGEVity trial evaluating a sequence of venetoclax and obinutuzumab followed by epcoritamab for untreated chronic lymphocytic leuke…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010). [Phase 3]
This Phase 3 clinical trial compares Nemtabrutinib plus Venetoclax versus Venetoclax plus Rituximab in second-line or relapsed/refractory ch…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Immune Profiling of CLL/SLL Treated With First-Line Pirtobrutinib [EARLY_Phase 1]
An early-phase trial evaluating immune profiling of first-line pirtobrutinib in chronic lymphocytic leukemia and small lymphocytic lymphoma …
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: A Study of BGB-21447, a Bcl-2 Inhibitor, in Mature B-Cell Malignancies [Phase 1]
Phase 1 clinical trial update of BGB-21447, a Bcl-2 inhibitor developed by BeOne Medicines, evaluating safety and preliminary activity in mu…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Economic Analysis of Early vs Delayed Therapy in Newly Diagnosed Asymptomatic High-Risk Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma:
A clinical trial update describes an economic analysis comparing early versus delayed therapy in newly diagnosed asymptomatic high-risk chro…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Ibrutinib, Fludarabine Phosphate, Cyclophosphamide, and Obinutuzumab in Treating Patients With Chronic Lymphocytic Leukemia [Phase 2]
This Phase 2 clinical trial update reports on a combination therapy of ibrutinib, fludarabine phosphate, cyclophosphamide, and obinutuzumab …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Study of BGB-11417 in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
BeiGene's BGB-11417 is being studied in a Phase 2 trial for relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphom…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) [Phase 1, Phase 2]
This clinical trial evaluates the safety and efficacy of JCAR017 in relapsed or refractory chronic lymphocytic leukemia and small lymphocyti…