Sjögren Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State [Phase 3]
Update on a Phase 3 clinical trial evaluating dazodalibep in Sjögren's syndrome, with the study currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Creating Health Course Study for People With Rheumatological Conditions [NA]
A new health course study for people with rheumatological conditions is currently recruiting, spanning rheumatoid arthritis, Sjögren's syndr…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Maternal Autoimmune Disease Research Alliance (MADRA) Registry
Duke University’s MADRA pregnancy autoimmune disease registry is actively recruiting to study autoimmune conditions during pregnancy, includ…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Exploring the Novel Value of PSMA PET in Sjögren's Syndrome: Integrated Analysis With Established FAPI PET Imaging [NA]
A clinical trial (NCT07324733) sponsored by Peking Union Medical College Hospital is investigating PSMA PET and FAPI PET imaging in primary …
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Effects of Phytocannabinoids on Immune Response and Autophagy During Chronic Immune-mediated Inflammatory Diseases
A clinical trial update indicates a study assessing the effects of phytocannabinoids on immune response and autophagy in chronic immune-medi…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases [NA]
This clinical trial is recruiting to evaluate anti-CD19 IL-10/IL-15 CAR-NK cells for refractory/relapsed autoimmune diseases. Conditions inc…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases. [Phase 2]
Phase 2 trial evaluating AlloNK, an allogeneic cord blood-derived NK cell therapy, in combination with Rituximab for relapsing B-cell–depend…
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CLINICAL_TRIALS other · 2025-12-24Clinical Trial Update: Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseases [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating BCT301 cell injection therapy for refractory autoimmune diseases, including systemic lupus erythe…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome [Phase 4]
A Phase 4 clinical trial update reports a new therapy for dry eye in patients with Sjögren's syndrome with keratoconjunctivitis, currently r…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: A Study of CD19 UCAR-T Cells in Subjects With Autoimmune Diseases [NA]
A clinical trial update evaluating CD19 UCAR-T cell therapy in autoimmune diseases; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Repeated Mesenchymal Stem Cell Therapy for Radiation-Induced Hyposalivation and Xerostomia in Head and Neck Cancer Survivors [Phase 2]
A Phase 2 clinical trial is evaluating repeated mesenchymal stem cell therapy for radiation-induced hyposalivation and xerostomia in head an…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Investigation of the Effectiveness of Cognitive Exercise Therapy Approach in Patients With Primary Sjögren's Syndrome [NA]
This clinical trial update indicates that the study investigating the effectiveness of Cognitive Exercise Therapy Approach in patients with …
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL PFS with1mL Pre-filled Syringe in Adult Participants With Autoimmune Disease [Phase 2]
Phase 2 two-period crossover study to demonstrate pharmacokinetic comparability of subcutaneous ianalumab administered with a 2 mL auto-inje…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Levocarnitine for Dry Eye in Sjogren's Syndrome [Phase 2]
Phase 2 trial of levocarnitine for dry eye in Sjögren's syndrome has completed. The study involved Keratoconjunctivitis Sicca as part of the…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Interferon Signature in Anti-CTLA-4 and Anti-PD-1/PD-L1-Treated Cancer Patients Compared With Systemic Autoimmune Disease Patients
A recruiting clinical trial examining interferon signature differences between cancer patients treated with anti-CTLA-4 or anti-PD-1/PD-L1 t…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases [Phase 4]
Phase 4 clinical trial update on the recombinant herpes zoster vaccine in patients with autoimmune rheumatic diseases; the study is active b…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Analyse of Inflammatory Activity of Sjögren's Syndrome on 68Ga-FAPI PET-CT [Phase 1, Phase 2]
A Phase 1/2 clinical trial at Peking Union Medical College Hospital evaluating the inflammatory activity of Sjögren's syndrome using 68Ga-FA…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: "Validity and Reliability of Pelvic Floor Distress Inventory-20 in Primary Sjögren's Syndrome"
Study update assessing the validity and reliability of the Pelvic Floor Distress Inventory-20 in individuals with Primary Sjögren's syndrome…
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CLINICAL_TRIALS trial_result · 2025-11-25Clinical Trial Update: Temporomandibular Joint Dysfunction in Sjögren's Syndrome
A completed clinical trial from Pamukkale University studied temporomandibular joint dysfunction in patients with Sjögren syndrome.
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CLINICAL_TRIALS trial_result · 2025-11-20Clinical Trial Update: Study to Evaluate Corneal Neurosensory Abnormalities in Patients With Sjögren's Dry Eye
A clinical trial evaluating corneal neurosensory abnormalities in Sjögren's syndrome with dry eye was terminated.
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Descriptive Study of Variations in Serum Translocation Markers of the Intestinal Microbiota in Patients With Gougerot-Sjögren Syndrome According to Disease Activity
An observational descriptive study evaluating variations in serum translocation markers of the intestinal microbiota in patients with Sjögre…
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: OM336 in Seropositive Autoimmune Diseases [Phase 1]
Phase 1 trial update for OM336 in seropositive autoimmune diseases; the study in Sjögren's syndrome and idiopathic inflammatory myopathy is …
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: A Study of Nipocalimab in Adults With Primary Sjogren's Syndrome (pSS) [Phase 2]
This update reports the completion of a Phase 2 study evaluating Nipocalimab in adults with primary Sjögren's syndrome.
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity [NA]
This document provides an update on a rheumatology-focused clinical trial sponsored by Brigham and Women's Hospital that studies an adaptive…
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Therapeutic Efficacy of SAR441344 in Primary Sjögren's Syndrome (pSjS) [Phase 2]
A Phase 2 study of SAR441344 in primary Sjögren's syndrome completed, with safety, tolerability, pharmacokinetics, and preliminary efficacy …