Sjögren Syndrome
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Efficacy and Safety of S95011 in Primary Sjögren's Syndrome Patients [Phase 2]
Phase 2 trial update reporting efficacy and safety results for S95011 in patients with Primary Sjögren's Syndrome; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-04-16Clinical Trial Update: CEQUA for Sjogren's Syndrome Dry Eye [Phase 4]
Phase 4 clinical trial update for CEQUA in Sjogren's syndrome–associated dry eye has completed enrollment.
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CLINICAL_TRIALS trial_result · 2024-02-20Clinical Trial Update: Tivanisiran for Dry Eye in Subjects With Sjögren's Syndrome [Phase 3]
Phase 3 clinical trial update for tivanisiran in dry eye due to Sjögren's syndrome has completed.
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CLINICAL_TRIALS trial_result · 2024-01-16Clinical Trial Update: Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis [Phase 2]
Phase 2 trial assessing Branebrutinib in active autoimmune diseases (systemic lupus erythematosus, primary Sjögren's syndrome) and rheumatoi…
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CLINICAL_TRIALS trial_result · 2023-09-22Clinical Trial Update: 68Ga-P16-093 PET/CT Imaging in the Salivary Gland [Phase 1, Phase 2]
A Phase 1/2 clinical trial investigating 68Ga-P16-093 PET/CT imaging for primary Sjögren syndrome.
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CLINICAL_TRIALS trial_result · 2023-09-18Clinical Trial Update: A Study Evaluating the Effects of GLPG3970 Given as an Oral Treatment for 12 Weeks in Adults With Active Primary Sjögren's Syndrome (pSS) [Phase 2]
Phase 2 study evaluating GLPG3970 for 12 weeks in adults with active primary Sjögren's syndrome was terminated; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjogren's Syndrome [Phase 2]
Phase 2 trial update evaluating safety and efficacy of multiple doses of CFZ533 in Sjögren's syndrome has completed.
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CLINICAL_TRIALS trial_result · 2023-02-17Clinical Trial Update: Clinical Study to Investigate the Efficacy of Orally Administered SA001 in Patients With Primary Sjögren's Syndrome [Phase 2]
A Phase 2 clinical trial investigating the efficacy of an oral agent SA001 in patients with primary Sjögren's syndrome has been completed.
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CLINICAL_TRIALS trial_result · 2022-12-20Clinical Trial Update: A Phase 2 Study to Evaluate the Safety and Efficacy of LOU064 in Patients With Moderate to Severe Sjögren's Syndrome [Phase 2]
A Phase 2 study evaluating safety and efficacy of LOU064 in patients with Sjögren's syndrome was terminated with results posted.
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CLINICAL_TRIALS trial_result · 2022-03-02Clinical Trial Update: Efficacy, Safety and Immunological Evaluation of Tofacitinib in the Treatment of Primary Sjogren's Syndrome [Phase 2]
Phase 2 trial evaluating efficacy, safety, and immune effects of tofacitinib in treating Primary Sjögren's Syndrome.
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CLINICAL_TRIALS trial_result · 2022-01-11Clinical Trial Update: A Study of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Primary Sjögren's Syndrome [Phase 2]
Phase 2 trial of RC18 (TACI-antibody fusion protein) in Primary Sjögren's Syndrome has completed.
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CLINICAL_TRIALS trial_result · 2021-07-19Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Iguratimod Compared to Placebo in Patients With Active Primary Sjogren's Syndrome. [Phase 2]
A Phase 2 clinical trial evaluating iguratimod versus placebo in active primary Sjogren's syndrome to assess efficacy and safety.
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CLINICAL_TRIALS trial_result · 2021-06-30Clinical Trial Update: A Prospective Pilot Study to Explore Efficacy and Safety of Baricitinib in Active Primary Sjogren's Syndrome Patients [Phase 1, Phase 2]
A prospective pilot study evaluating the efficacy and safety of baricitinib in active primary Sjogren's syndrome across Phase 1 and Phase 2 …
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CLINICAL_TRIALS trial_result · 2021-06-04Clinical Trial Update: Exploratory Study for Dry Mouth in Patients With Sjögren's Syndrome [Phase 2]
Phase 2 exploratory trial studying dry mouth in Sjögren's syndrome; completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-03-24Clinical Trial Update: A Study of INCB050465 in Primary Sjögren's Syndrome [Phase 2]
Phase 2 study of INCB050465 in Primary Sjögren's Syndrome has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Lacripep™ in Subjects With Dry Eye Associated With Primary Sjögren's Syndrome [Phase 1, Phase 2]
Phase 1/2 clinical trial update for Lacripep in dry eye associated with Primary Sjögren's Syndrome.
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CLINICAL_TRIALS trial_result · 2020-01-02Clinical Trial Update: A Study to Assess the Efficacy and Safety of Abatacept in Adults With Active Primary Sjögrens Syndrome [Phase 3]
Phase 3 trial evaluating abatacept for active primary Sjögren's syndrome has completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2019-10-01Clinical Trial Update: A Clinical Trial to Evaluate the Safety and Efficacy of Traditional Chinese Medicine in Sjögren's Syndrome. [Phase 2]
Phase 2 clinical trial evaluating safety and efficacy of Traditional Chinese Medicine in Sjögren's Syndrome has completed.
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: Efficacy and Safety of Abatacept in Patients With Primary Sjögren's Syndrome [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of abatacept in patients with primary Sjögren's syndrome has completed.
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CLINICAL_TRIALS trial_result · 2019-08-14Clinical Trial Update: Safety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Primary Sjögren's Syndrome [Phase 2]
Phase 2 clinical trial evaluating CFZ533 in patients with primary Sjögren's syndrome has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-03-19Clinical Trial Update: A Phase 2a, Randomized, Placebo Controlled, Study to Evaluate the Safety and Efficacy of AMG 557/MEDI5872 in Primary Sjögren's Syndrome [Phase 2]
Phase 2a randomized, placebo-controlled trial evaluating safety and efficacy of AMG 557/MEDI5872 in Primary Sjögren's Syndrome completed wit…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Minor Salivary Gland Transplantation for Cicatrizing Conjunctivitis [NA]
This clinical trial update describes a study of minor salivary gland transplantation for cicatricial conjunctivitis, sponsored by National T…
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: PD of VAY736 in Patients With Primary Sjögren's Syndrome [Phase 2]
Phase 2 trial update for VAY736 in patients with Primary Sjögren's Syndrome has completed with results posted.
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CLINICAL_TRIALS trial_result · 2018-12-04Clinical Trial Update: Comparison Between Rebamipide 2% Versus Autologous Serum [Phase 4]
Phase 4 trial comparing rebamipide 2% to autologous serum in patients with dry eye syndromes and Sjögren syndrome has completed.
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CLINICAL_TRIALS trial_result · 2018-11-02Clinical Trial Update: Dexamethasone Irrigation of the Parotid Glands in Primary Sjögren's Syndrome Subjects [Phase 2]
Phase 2 trial evaluating dexamethasone irrigation of parotid glands in Sjögren's syndrome with xerostomia; study terminated with results pos…