Sjögren Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Diseases [Phase 1]
Phase 1 trial update on YTS109 cell therapy for relapsed/refractory autoimmune diseases, currently recruiting across multiple indications.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: YTS109 in Pediatric Relapsed/Refractory Autoimmune Diseases [Phase 1]
A Phase 1 clinical trial evaluating YTS109 in pediatric relapsed/refractory autoimmune diseases, including SLE and diffuse systemic sclerosi…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA U CAR-T Cell Injection for the Treatment of Relapsed/Refractory Autoimmune Diseases [EARLY_Phase 1]
An early-phase exploratory clinical study evaluating the safety and potential efficacy of an anti-CD19/BCMA U CAR-T cell therapy for relapse…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: A Clinical Study of TI-0032-III Injection in Patients With Relapsed and Refractory Autoimmune Diseases [Phase 1]
A Phase 1 clinical trial of TI-0032-III Injection for relapsed and refractory autoimmune diseases is currently recruiting, encompassing seve…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Primary Sjögren's Syndrome: Impact of Quantitative Anti-Ro52 Antibody Analysis on Patient Prognosis and Stratification (Ro-SjS)
This clinical trial update investigates how quantitative anti-Ro52 antibody analysis may affect prognosis and patient stratification in Sjög…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Dose-Escalation Trial of Mesenchymal Stromal Cells in Patients With Medical Xerostomia [Phase 1]
This entry reports a Phase 1 dose-escalation trial of mesenchymal stromal cells for medical xerostomia, including patients with graft-versus…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: A PHASE II PROSPECTIVE RANDOMIZED DOUBLE-MASKED CONTROLLED STUDY ASSESSING THE SAFETY & EFFICACY OF RHPRG4 (450 µG/ML RECOMBINANT HUMAN PROTEOGLYCAN 4) COMPARED TO VEHICLE FOR THE TREATMENT OF SJÖGREN'S RELATED DRY EYE DISEASE [Phase 2]
A Phase II randomized, double-masked trial is evaluating the safety and efficacy of rhPRG4 for Sjögren's-related dry eye disease and is curr…
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Medico-economic and Quality of Life Impact of Sjogren-associated Small Fiber Neuropathy
This clinical trial is assessing the medico-economic impact and quality-of-life effects of Sjögren-associated small fiber neuropathy and is …
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: A Phase 2 Study on the Safety and Efficacy of the Anti-BAFF-R Monoclonal Antibody, ESG206, in Patients With Primary Sjogren Syndrome [Phase 2]
A Phase 2 trial evaluating ESG206, an anti-BAFF-R monoclonal antibody, for Primary Sjögren's syndrome, with the study currently not recruiti…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Autologous CD19/BCMA Dual-Target CAR-T for Relapsed/Refractory Autoimmune Diseases [Phase 1]
Phase 1 trial evaluating autologous CD19/BCMA dual-target CAR-T therapy for relapsed/refractory autoimmune diseases; currently recruiting at…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activity [Phase 3]
An Amgen-sponsored Phase 3 trial evaluating the efficacy and safety of Dazodalibep for Sjögren's syndrome with moderate-to-severe systemic d…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State [Phase 3]
Update on a Phase 3 clinical trial evaluating dazodalibep in Sjögren's syndrome, with the study currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Creating Health Course Study for People With Rheumatological Conditions [NA]
A new health course study for people with rheumatological conditions is currently recruiting, spanning rheumatoid arthritis, Sjögren's syndr…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Maternal Autoimmune Disease Research Alliance (MADRA) Registry
Duke University’s MADRA pregnancy autoimmune disease registry is actively recruiting to study autoimmune conditions during pregnancy, includ…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Exploring the Novel Value of PSMA PET in Sjögren's Syndrome: Integrated Analysis With Established FAPI PET Imaging [NA]
A clinical trial (NCT07324733) sponsored by Peking Union Medical College Hospital is investigating PSMA PET and FAPI PET imaging in primary …
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Effects of Phytocannabinoids on Immune Response and Autophagy During Chronic Immune-mediated Inflammatory Diseases
A clinical trial update indicates a study assessing the effects of phytocannabinoids on immune response and autophagy in chronic immune-medi…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases [NA]
This clinical trial is recruiting to evaluate anti-CD19 IL-10/IL-15 CAR-NK cells for refractory/relapsed autoimmune diseases. Conditions inc…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases. [Phase 2]
Phase 2 trial evaluating AlloNK, an allogeneic cord blood-derived NK cell therapy, in combination with Rituximab for relapsing B-cell–depend…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: A Study of CD19 UCAR-T Cells in Subjects With Autoimmune Diseases [NA]
A clinical trial update evaluating CD19 UCAR-T cell therapy in autoimmune diseases; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Repeated Mesenchymal Stem Cell Therapy for Radiation-Induced Hyposalivation and Xerostomia in Head and Neck Cancer Survivors [Phase 2]
A Phase 2 clinical trial is evaluating repeated mesenchymal stem cell therapy for radiation-induced hyposalivation and xerostomia in head an…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Two-period Crossover Study to Demonstrate the Comparability of Pharmacokinetics of Subcutaneous Ianalumab Between 2mL Auto-injector/2mL PFS with1mL Pre-filled Syringe in Adult Participants With Autoimmune Disease [Phase 2]
Phase 2 two-period crossover study to demonstrate pharmacokinetic comparability of subcutaneous ianalumab administered with a 2 mL auto-inje…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Interferon Signature in Anti-CTLA-4 and Anti-PD-1/PD-L1-Treated Cancer Patients Compared With Systemic Autoimmune Disease Patients
A recruiting clinical trial examining interferon signature differences between cancer patients treated with anti-CTLA-4 or anti-PD-1/PD-L1 t…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Analyse of Inflammatory Activity of Sjögren's Syndrome on 68Ga-FAPI PET-CT [Phase 1, Phase 2]
A Phase 1/2 clinical trial at Peking Union Medical College Hospital evaluating the inflammatory activity of Sjögren's syndrome using 68Ga-FA…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: "Validity and Reliability of Pelvic Floor Distress Inventory-20 in Primary Sjögren's Syndrome"
Study update assessing the validity and reliability of the Pelvic Floor Distress Inventory-20 in individuals with Primary Sjögren's syndrome…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Descriptive Study of Variations in Serum Translocation Markers of the Intestinal Microbiota in Patients With Gougerot-Sjögren Syndrome According to Disease Activity
An observational descriptive study evaluating variations in serum translocation markers of the intestinal microbiota in patients with Sjögre…