Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2013-10-22Clinical Trial Update: Activated Protein C and Microcirculation
A completed clinical trial examining activated protein C and its effects on microcirculation in patients with severe sepsis and septic shock…
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EMA safety_alert · 2013-10-11PRAC confirms that hydroxyethyl-starch solutions (HES) should no longer be used in patients with sepsis or burn injuries or in critically ill patients
PRAC confirms that hydroxyethyl-starch solutions should no longer be used in patients with sepsis, burn injuries, or in critically ill patie…
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CLINICAL_TRIALS trial_result · 2013-10-01Clinical Trial Update: Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients
A completed clinical trial assessing how acute respiratory distress syndrome and severe sepsis influence soluble RAGE (sRAGE) levels in ICU …
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CLINICAL_TRIALS trial_result · 2013-09-27Clinical Trial Update: Hydrocortisone for Prevention of Septic Shock [Phase 3]
Phase 3 trial evaluating hydrocortisone for prevention of septic shock has completed.
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CLINICAL_TRIALS trial_result · 2013-09-27Clinical Trial Update: Skeletal Muscle and Platelet Mitochondrial Dysfunction During Sepsis
A clinical trial studying skeletal muscle and platelet mitochondrial dysfunction during sepsis has completed.
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CLINICAL_TRIALS trial_result · 2013-09-23Clinical Trial Update: A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock [Phase 2]
This document reports the results of a Phase 2 trial comparing two IV dosing regimens of AZD9773 (CytoFab) versus placebo in adults with sev…
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CLINICAL_TRIALS research · 2013-09-20Clinical Trial Update: Catheter Early Withdrawal or Maintenance in Sepsis or Septic Shock [NA]
This clinical trial update concerns NCT01947751, a study comparing early withdrawal versus maintenance of a catheter in patients with sepsis…
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CLINICAL_TRIALS trial_result · 2013-08-30Clinical Trial Update: Acute Kidney Injury in Septic Critically Ill Patients : Are Aminoglycosides Really Harmful?
A completed clinical trial investigated whether aminoglycoside antibiotics worsen acute kidney injury in septic, critically ill patients.
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CLINICAL_TRIALS trial_result · 2013-08-22Clinical Trial Update: A Study to Assess Safety,and Tolerability of 2 Doses of AZD9773 (CytoFab™) in Japanese With Severe Sepsis/Septic Shock [Phase 2]
Phase 2 study evaluating two doses of AZD9773 (CytoFab) in Japanese patients with severe sepsis or septic shock to assess safety and tolerab…
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CLINICAL_TRIALS trial_result · 2013-08-22Clinical Trial Update: AZD9773 Dose Escalation Study [Phase 2]
Phase 2 dose-escalation trial of AZD9773 in sepsis has completed and results have been posted.
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CLINICAL_TRIALS research · 2013-08-09Clinical Trial Update: Identification Sepsis Related Single Nucleotide Polymorphism (SNP) by Whole Exome Sequencing
A clinical trial sponsored by the Chinese PLA General Hospital aims to identify sepsis-related single nucleotide polymorphisms using whole e…
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CLINICAL_TRIALS research · 2013-08-07Clinical Trial Update: Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter [NA]
This clinical trial update discusses evaluating teicoplanin for treating septicemia in cancer patients receiving chemotherapy through a cent…
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CLINICAL_TRIALS withdrawal · 2013-07-19Clinical Trial Update: Determination of the Nature of the Endogenous Ligand of TREM-1 and Its Use as a New Diagnostic Biomarker in Sepsis
The clinical trial evaluating the endogenous ligand of TREM-1 as a diagnostic biomarker for sepsis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2013-07-19Clinical Trial Update: Epidemiology of Septic Shock in Medical or Polyvalent ICU in the North-East Region of France
A clinical trial examining the epidemiology of septic shock in ICUs in northeast France has been terminated.
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CLINICAL_TRIALS trial_result · 2013-07-12Clinical Trial Update: Infected Elders in the Emergency Department: Outcomes and Processes of Care
This clinical trial update reports on outcomes and care processes for elderly patients with sepsis presenting to the emergency department.
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CLINICAL_TRIALS trial_result · 2013-07-11Clinical Trial Update: Randomized Trial of Inhaled Nitric Oxide to Augment Tissue Perfusion in Sepsis [Phase 3]
A Phase 3 randomized trial evaluated inhaled nitric oxide to augment tissue perfusion in sepsis; the study is completed and results were pos…
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CLINICAL_TRIALS trial_result · 2013-07-08Clinical Trial Update: Zinc and Inflammation in Sepsis
The clinical trial evaluating zinc and inflammation in sepsis has completed.
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CLINICAL_TRIALS trial_result · 2013-06-27Clinical Trial Update: The Effects of Immunostimulation With GM-CSF or IFN-y on Immunoparalysis Following Human Endotoxemia [NA]
This clinical trial evaluated whether immunostimulation with GM-CSF or interferon-gamma can counteract immunoparalysis after endotoxemia; th…
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CLINICAL_TRIALS trial_result · 2013-06-19Clinical Trial Update: Investigation of the Accuracy of Temporal Artery Thermometers
A completed clinical trial evaluating the accuracy of temporal artery thermometers in patients with sepsis.
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CLINICAL_TRIALS trial_result · 2013-06-07Clinical Trial Update: Serum TNF-a in Comparison to Sequential Organ Failure Assessment (SOFA) Score Monitoring in Critically Ill Patients
This completed clinical trial evaluated whether serum TNF-α measurement provides monitoring comparable to the SOFA score in critically ill p…
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CLINICAL_TRIALS trial_result · 2013-06-04Clinical Trial Update: The Impact of IVIG Treatment on Critical Illness Polyneuropathy and/or Myopathy in Patients With MOF and SIRS/Sepsis [Phase 1]
Phase 1 trial assessing intravenous immunoglobulin for critical illness polyneuropathy and/or myopathy in patients with multiple organ failu…
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CLINICAL_TRIALS trial_result · 2013-05-30Clinical Trial Update: Pharmacokinetics and Safety of Piperacillin-tazobactam in Neonates [Phase 1]
Phase 1 pharmacokinetics and safety study of piperacillin-tazobactam in neonates for sepsis completed; results posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-05-21Clinical Trial Update: Efficacy of Melatonin in Patients With Severe Sepsis or Septic Shock [Phase 3]
Phase 3 clinical trial evaluating the efficacy of melatonin in patients with severe sepsis or septic shock; current status is unknown.
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CLINICAL_TRIALS trial_result · 2013-05-09Clinical Trial Update: Melatonin in Healthy Volunteers [Phase 1]
A Phase 1 study of melatonin in healthy volunteers sponsored by the University of Aberdeen has completed; the trial lists sepsis as a condit…
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CLINICAL_TRIALS trial_result · 2013-05-03Clinical Trial Update: Circulating microRNAs as Biomarkers of Sepsis
A completed clinical trial evaluating circulating microRNAs as biomarkers for sepsis.