Sepsis
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CLINICAL_TRIALS trial_result · 2014-09-12Clinical Trial Update: Indicators of Inflammation and Coagulation in Sepsis
This entry notes that a clinical trial investigating markers of inflammation and coagulation in sepsis has completed.
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CLINICAL_TRIALS trial_result · 2014-09-09Clinical Trial Update: Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients [NA]
A completed clinical trial evaluating glutamine and antioxidant supplementation in critically ill patients, with results posted in 2014.
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CLINICAL_TRIALS research · 2014-09-01Clinical Trial Update: Sepsis in Neutropenic Patients: Autologous Stem Cell Transplantation as Model: a Transcriptomic Approach [NA]
A clinical trial update exploring sepsis in neutropenic patients using autologous stem cell transplantation as a model, with transcriptomic …
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CLINICAL_TRIALS research · 2014-08-20Clinical Trial Update: International Multicentre Prevalence Study on Sepsis
This document notes the completion of an international multicentre prevalence study on sepsis. It covers severe sepsis and septic shock.
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CLINICAL_TRIALS research · 2014-08-11Clinical Trial Update: Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem During the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units [Phase 4]
This Phase 4 clinical trial update reports population pharmacokinetics and Monte Carlo dosing simulations of meropenem in the early phase of…
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CLINICAL_TRIALS trial_result · 2014-07-31Clinical Trial Update: Chlorhexidine Vaginal and Infant Wash in Pakistan [Phase 3]
Clinical Trial Update indicating the Phase 3 trial of chlorhexidine vaginal and infant wash in Pakistan has completed.
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CLINICAL_TRIALS trial_result · 2014-07-31Clinical Trial Update: Prevention of Infection in Indian Neonates - Phase I Observational Study
Phase I observational trial evaluating infection prevention in Indian neonates has completed, with sepsis as the primary focus.
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CLINICAL_TRIALS research · 2014-07-30Clinical Trial Update: Electric Acupuncture for ICU-acquired Weakness in Mechanical Ventilation Patients [NA]
This clinical trial update describes a study evaluating electric acupuncture for ICU-acquired weakness in mechanically ventilated patients, …
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CLINICAL_TRIALS research · 2014-07-22Clinical Trial Update: Inferior Vena Cava Collapsibility Index in Severe Sepsis [NA]
This entry reports an ongoing clinical investigation into the inferior vena cava collapsibility index as a diagnostic/monitoring tool in sev…
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CLINICAL_TRIALS trial_result · 2014-07-16Clinical Trial Update: Effect Study of Tigecycline to Treat Severe Sepsis and Septic Shock [Phase 2, Phase 3]
A clinical trial update on tigecycline for severe sepsis and septic shock (Phase 2/Phase 3) with abdominal infection as a condition; the cur…
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CLINICAL_TRIALS research · 2014-07-09Clinical Trial Update: Effects of Subanesthetic Isoflurane/Sevoflurane in 60% Oxygen on Clinical In-vitro Experimental Sepsis [NA]
Clinical trial update examining the effects of subanesthetic doses of isoflurane and sevoflurane in 60% oxygen on in-vitro models of sepsis.
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CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in Sepsis [Phase 3]
Phase 3 trial assessing the impact of low-dose unfractionated heparin on inflammation in sepsis has completed.
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CLINICAL_TRIALS trial_result · 2014-07-01Clinical Trial Update: Ascorbic Acid (Vitamin C) Infusion in Human Sepsis [Phase 1, Phase 2]
Phase 1/2 clinical trial of ascorbic acid infusion in humans with sepsis/septic shock has been completed with posted results.
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CLINICAL_TRIALS trial_result · 2014-06-25Clinical Trial Update: Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock [Phase 4]
Phase 4 trial comparing Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) to Early Goal-Directed Therapy (EGDT) in septic s…
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CLINICAL_TRIALS trial_result · 2014-06-24Clinical Trial Update: Outcomes of Severe Sepsis Patients in Surgical Intensive Care Units
A completed clinical trial conducted by National Taiwan University Hospital evaluating outcomes for severe sepsis and septic shock patients …
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CLINICAL_TRIALS research · 2014-06-13Clinical Trial Update: Prevalence and Outcome of Hypermetabolism in Initial Prevalence and Outcome of Hypermetabolism in Initial Phase of Intensive Care Unit Patient: a Prospective Observational Study
This clinical trial update describes a prospective observational study that assesses how common hypermetabolism is in the early phase of ICU…
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CLINICAL_TRIALS trial_result · 2014-05-23Clinical Trial Update: Sepsis Pathophysiological & Organisational Timing
This clinical trial update reports on a completed study investigating the pathophysiology of sepsis and the impact of timing on organisation…
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CLINICAL_TRIALS trial_result · 2014-05-20Clinical Trial Update: Experimental Determination of Atot en Ka in the Critically Ill
Completed clinical trial assessing pharmacokinetic parameters Atot and Ka in critically ill patients with sepsis or undergoing CABG.
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CLINICAL_TRIALS withdrawal · 2014-05-20Clinical Trial Update: Safety of Heparin in Patients With Septic Shock [Phase 2]
A Phase 2 trial evaluating the safety of heparin in patients with septic shock has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-05-13Clinical Trial Update: Albumin Administration in Cirrhotic Patients With Bacterial Infection and a Systemic Inflammatory Response Syndrome Unrelated to Spontaneous Bacterial Peritonitis [Phase 3]
A Phase 3 trial evaluating albumin administration in cirrhotic patients with bacterial infection and a systemic inflammatory response syndro…
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: The Effect of Ketanserin on the Microcirculation in Sepsis [Phase 3]
A Phase 3 clinical trial evaluating ketanserin's effect on microcirculation in patients with sepsis has completed.
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: Effect of Midazolam on Inflammatory Response and Organ Function in Mechanically Ventilated Sepsis Patients With Different Immune Status [Phase 4]
Phase 4 clinical trial update investigating the effect of midazolam on inflammatory response and organ function in mechanically ventilated s…
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CLINICAL_TRIALS trial_result · 2014-05-01Clinical Trial Update: Antimicrobial Stewardship Reduces MDRO Isolates in Critically Ill Patients
A completed clinical trial update shows that antimicrobial stewardship interventions reduced multidrug-resistant organism isolates in critic…
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CLINICAL_TRIALS trial_result · 2014-04-29Clinical Trial Update: Lactate Use as Triage Tool in Sepsis : Veinous, Capillary or Arterial?
This document provides an update on a completed clinical trial evaluating the use of lactate testing as a triage tool for sepsis, comparing …
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CLINICAL_TRIALS trial_result · 2014-04-25Clinical Trial Update: Mitochondrial Function of Immune Cells in Sepsis
This document reports the completion of a clinical trial studying mitochondrial function of immune cells in sepsis, including septic shock.