Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-05-27Clinical Trial Update: Protective Effects of Delayed Cord Clamping in Very Low Birth Weight (VLBW) Infants [Phase 2]
Phase 2 trial update evaluating delayed cord clamping in very low birth weight infants and its potential to reduce intraventricular hemorrha…
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CLINICAL_TRIALS trial_result · 2015-05-21Clinical Trial Update: rhTPO in Critical Patients With Thrombocytopenia [Phase 2, Phase 3]
An ongoing Phase 2/Phase 3 trial investigates recombinant human thrombopoietin (rhTPO) in critically ill patients with thrombocytopenia, inc…
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CLINICAL_TRIALS trial_result · 2015-05-20Clinical Trial Update: Bioimpedance Analysis in Septic Intensive Care Unit (ICU) Patients
A completed clinical trial evaluating the use of bioimpedance analysis in septic intensive care unit patients.
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CLINICAL_TRIALS trial_result · 2015-05-20Clinical Trial Update: Using Sodium Lactate Ringer's Injection Resuscitate Septic Shock Patients [NA]
Clinical trial update about using Lactated Ringer's solution to resuscitate patients with sepsis and septic shock; the current status of the…
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: Effects of BCG on Immune Response [Phase 2, Phase 3]
Radboud University Medical Center completed Phase 2 and Phase 3 trials evaluating the effects of Bacillus Calmette-Guérin (BCG) on immune re…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Venous Lactate in Progression to Overt Septic Shock and Mortality in Non-elderly Sepsis Patients in Emergency Department
The trial evaluated venous lactate as a predictor of progression to overt septic shock and mortality in non-elderly sepsis patients in the e…
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CLINICAL_TRIALS research · 2015-05-04Clinical Trial Update: Inflammatory Cytokine Quantification in Infants
Completed clinical trial in infants analyzing inflammatory cytokine levels in sepsis and congenital diaphragmatic hernia.
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: De-escalation of Empirical Antimicrobial Therapy Study in Severe Sepsis [Phase 3]
A Phase 3 clinical trial updating the de-escalation of empirical antimicrobial therapy in severe sepsis has completed.
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CLINICAL_TRIALS trial_result · 2015-04-21Clinical Trial Update: Neutrophil Gelatinase Associated Lipocalin (NGAL) in Urine: Can This Prove to be a Biomarker for Acute Kidney Injury in Patients With Sepsis?
ClinicalTrials.gov update notes that a study evaluating urinary NGAL as a biomarker for acute kidney injury in patients with sepsis/septic s…
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CLINICAL_TRIALS trial_result · 2015-04-20Clinical Trial Update: Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) [NA]
A completed clinical trial evaluating the efficacy of hydrocortisone in treatment of severe sepsis or septic shock with acute lung injury/ac…
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CLINICAL_TRIALS trial_result · 2015-04-14Clinical Trial Update: Biomarker Analysis of Stress
This NIEHS-sponsored clinical trial's completed biomarker analysis examines stress-related biomarkers in patients with sepsis. The report do…
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CLINICAL_TRIALS trial_result · 2015-04-10Clinical Trial Update: Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome [Phase 2]
Phase 2 clinical trial update of ALT-836 (anti-TF antibody) in septic patients with acute lung injury or acute respiratory distress syndrome…
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CLINICAL_TRIALS trial_result · 2015-04-06Clinical Trial Update: Clinical and Economic Outcome of Simvastatin in Critically Ill Septic Patient [Phase 3]
Phase 3 clinical trial update evaluating the clinical and economic outcomes of simvastatin in critically ill patients with sepsis.
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: Randomized, Parallel Group, Placebo Control, Unicentric, Interventional Study to Assess the Effect of Expanded Human Allogeneic Adipose-derived Mesenchymal Adult Stem Cells on the Human Response to Lipopolysaccharyde in Human Volunteers [Phase 1]
A completed Phase 1 randomized, placebo-controlled, unicentric interventional study evaluating the safety and potential effects of expanded …
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CLINICAL_TRIALS trial_result · 2015-03-31Clinical Trial Update: Electronic Application of a Severe Sepsis Screening Tool and Management Bundle
This clinical trial update describes an electronic application of a severe sepsis screening tool and management bundle. The current status i…
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CLINICAL_TRIALS trial_result · 2015-03-24Clinical Trial Update: A Multi-Site Study of Music Therapy Interventions on Vitals, Feeding and Sleep in Premature Infants [NA]
Completed, multi-site clinical trial evaluating music therapy interventions on vitals, feeding, and sleep in premature infants, including th…
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CLINICAL_TRIALS trial_result · 2015-03-23Clinical Trial Update: Acetaminophen for the Reduction of Oxidative Injury in Severe Sepsis [Phase 2]
Phase 2 trial investigating acetaminophen to reduce oxidative injury in severe sepsis has completed and posted results.
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CLINICAL_TRIALS trial_result · 2015-03-17Clinical Trial Update: Procalcitonin Monitoring Sepsis Study
The clinical trial evaluating procalcitonin-based monitoring in sepsis has completed.
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CLINICAL_TRIALS trial_result · 2015-03-10Clinical Trial Update: Septic Encephalopathy and Late Cognitive Dysfunction [Phase 4]
Phase 4 clinical trial update examining septic encephalopathy and late cognitive dysfunction in sepsis patients; the study has completed.
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CLINICAL_TRIALS trial_result · 2015-02-18Clinical Trial Update: Pharmacokinetic/Pharmacodynamic Evaluation Amikacin in Critically Ill Patients Admitted at the Emergency Department [Phase 4]
Phase 4 pharmacokinetic/pharmacodynamic evaluation of amikacin in critically ill sepsis patients admitted from the emergency department has …
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CLINICAL_TRIALS trial_result · 2015-02-18Clinical Trial Update: Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care [NA]
A completed clinical trial update focused on optimizing diagnosis and antibiotic prescribing for acutely ill children in primary care.
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CLINICAL_TRIALS trial_result · 2015-02-16Clinical Trial Update: Efficacy, Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days With Clinical or Confirmed Late-onset Sepsis [Phase 3]
A Phase 3 trial evaluating Meropenem in infants under 90 days with late-onset sepsis has completed. The update reports on its efficacy, phar…
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CLINICAL_TRIALS research · 2015-02-09Clinical Trial Update: HO-1 and Muscle Mitochondrial Dysfunction in Sepsis
This clinical trial update discusses the role of heme oxygenase-1 (HO-1) in muscle mitochondrial dysfunction and atrophy during sepsis, spon…
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CLINICAL_TRIALS trial_result · 2015-02-04Clinical Trial Update: Effect of C1-esterase Inhibitor on Systemic Inflammation in Trauma Patients With a Femur or Pelvic Fracture [Phase 3]
Phase 3 trial evaluating C1-esterase inhibitor to reduce systemic inflammation in trauma patients with femur or pelvic fractures was termina…
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CLINICAL_TRIALS trial_result · 2015-02-03Clinical Trial Update: VTE Incidence in Severe Sepsis and Septic Shock
The update reports on venous thromboembolism incidence in patients with severe sepsis and septic shock from the NCT02353910 trial. The study…