Sepsis
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Amendment of rTSST-1 Variant Vaccine Phase 1 Clinical Trial [Phase 1]
This document reports an amendment to a Phase 1 trial and completion of a study evaluating an rTSST-1 variant vaccine for toxic shock syndro…
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults [Phase 2]
A Phase 2 clinical trial update from GlaxoSmithKline evaluating GR270773 for suspected or confirmed gram-negative severe sepsis in adults; t…
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CLINICAL_TRIALS research · 2017-05-04Clinical Trial Update: The Benefits of Early Initiation of Continual Renal Replacement Therapy in Patients With Severe Sepsis
This clinical trial update discusses the potential benefits of early initiation of continuous renal replacement therapy in patients with sep…
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CLINICAL_TRIALS research · 2017-05-01Clinical Trial Update: The 'Bekele Afessa Scan-Teach-Treat Approach' [NA]
This entry provides a clinical trial update for the Bekele Afessa Scan-Teach-Treat approach, sponsored by the University of Salzburg, with c…
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CLINICAL_TRIALS research · 2017-04-28Clinical Trial Update: Pharmacokinetics and Pharmacodynamics of Ceftazidime in Pediatric ICU Patients
This clinical trial update investigates the pharmacokinetics and pharmacodynamics of ceftazidime in pediatric ICU patients being treated for…
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Pharmacokinetic Study of Antibiotics in Patients Assisted by Extracorporeal Membrane Oxygenation (PHARMECMO)
This is a completed pharmacokinetic study of antibiotics in patients supported by extracorporeal membrane oxygenation (PHARMECMO), with the …
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Balanced Salt Solution VS. Normal Saline Solution in Septic Shock [Phase 3]
Phase 3 trial comparing Balanced Salt Solution to Normal Saline in septic shock has completed.
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Study of Primary Fascial Closure Rate in Patients With Open Abdomen Treated With Abthera Versus Barker Technique [Phase 3]
Phase 3 clinical trial comparing Abthera negative pressure therapy to the Barker technique for primary fascial closure after open abdomen; t…
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Continuous Monitoring on the General Ward [NA]
This is a completed clinical trial update from Radboud University Medical Center about continuous monitoring on the general ward. It lists p…
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: Ubiquinol (Reduced COQ10) for Patients With Sepsis [Phase 2]
Phase 2 trial evaluating ubiquinol (reduced CoQ10) for sepsis has completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-04-21Clinical Trial Update: Efficacy of Macrolide Immunomodulation in Severe Sepsis. [Phase 2]
A Phase 2 clinical trial evaluating macrolide-based immunomodulation in severe sepsis was terminated. The update references efficacy assessm…
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CLINICAL_TRIALS withdrawal · 2017-04-21Clinical Trial Update: Dose Assessment of Melatonin in Sepsis Trial [Phase 1, Phase 2]
A dose-assessment trial of melatonin for sepsis (Phase 1/Phase 2) has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: Evaluation of the Patient Safety Screening Tool (PSST) for Sepsis
The clinical trial evaluating the Patient Safety Screening Tool (PSST) for sepsis has been terminated. The update does not provide trial res…
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CLINICAL_TRIALS trial_result · 2017-04-19Clinical Trial Update: Fish OIL Optimal dosE Determination Study [Phase 2]
Phase 2 study evaluating the optimal dosing of fish oil for sepsis was terminated.
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CLINICAL_TRIALS withdrawal · 2017-04-17Clinical Trial Update: Early Goal Directed Therapy in Sepsis by Emergency Medical Services [NA]
A clinical trial studying Early Goal Directed Therapy in sepsis by Emergency Medical Services has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-04-14Clinical Trial Update: IMproved PREdiction of Severe Sepsis in the Emergency Department
Completed clinical trial evaluating improved prediction of severe sepsis in the emergency department, sponsored by Axis Shield Diagnostics L…
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CLINICAL_TRIALS research · 2017-04-14Clinical Trial Update: Descriptive Study of the Evolution in Proportion of Regulatory B Lymphocytes in Patients Hospitalized in Intensive Care for Severe Sepsis [NA]
A descriptive clinical study reviewing how the proportion of regulatory B lymphocytes evolves in ICU patients with severe sepsis. The study …
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: The Vital Signs to Identify, Target, and Assess Level (VITAL) Care Study III
A Philips Healthcare–sponsored clinical trial, the VITAL Care Study III, has completed. The study covers Cardiac arrest, Renal failure, Resp…
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: Early Insulin and Development of ARDS [Phase 2]
Phase 2 trial evaluating early insulin therapy in adults at risk of ARDS with sepsis and hyperglycemia; results have been completed and post…
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CLINICAL_TRIALS trial_result · 2017-04-10Clinical Trial Update: Therapeutic Effect of Sodium Selenite on Oxidative Stress in Patients With Severe Sepsis
This clinical trial update reports on the therapeutic effect of sodium selenite on oxidative stress in patients with severe sepsis. The stud…
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CLINICAL_TRIALS withdrawal · 2017-04-05Clinical Trial Update: Comparing an Automated to a Conventional Sepsis Clinical Prediction Rule
A clinical trial comparing an automated versus conventional sepsis clinical prediction rule was withdrawn from the study registry.
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Serum Procalcitonin Level May Predict Acute Kidney Injury in ICU Patients With Sepsis
A completed clinical trial indicates that serum procalcitonin level may help predict acute kidney injury in ICU patients with sepsis.
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Clinical Score Usefulness and EHR Integration
This completed clinical trial assessed the usefulness of a clinical scoring system for sepsis and its integration into electronic health rec…
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CLINICAL_TRIALS trial_result · 2017-03-22Clinical Trial Update: Methionine Metabolism in Parenterally Fed Pediatric Sepsis
This clinical trial update reports on a completed study evaluating methionine metabolism in pediatric patients with sepsis who are receiving…
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CLINICAL_TRIALS research · 2017-03-22Clinical Trial Update: Methionine Metabolism in Enterally Fed Pediatric Sepsis
A completed clinical trial from The Cleveland Clinic investigated methionine metabolism in enterally fed pediatric patients with sepsis and …