Sepsis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-06-14Clinical Trial Update: Effect of Metabolic Dysfunction in Branched-chain Amino Acids on Cardiac Function in Patients With Sepsis
A clinical trial is investigating whether metabolic dysfunction in branched-chain amino acids affects cardiac function in patients with seps…
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CLINICAL_TRIALS withdrawal · 2024-06-14Clinical Trial Update: Reducing 30-Day Sepsis Readmissions: Impact of a Post Discharge Education Program [NA]
A clinical trial evaluating a post-discharge education program to reduce 30-day sepsis readmissions has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-06-14Clinical Trial Update: Fluconazole Versus Micafungin for Candida Bloodstream Infection in Non-Neutropenic Patients [Phase 4]
Phase 4 trial comparing fluconazole versus micafungin for candidemia in non-neutropenic patients has been withdrawn.
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CLINICAL_TRIALS research · 2024-06-13Clinical Trial Update: Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
A trial update describing the Acutelines biobank for acute and emergency medicine; recruitment is ongoing across multiple acute conditions.
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Utility of Ultrasound Assessment of the Inferior Vena Cava in Patients With Sepsis and Dehydration [NA]
A terminated clinical trial evaluated whether ultrasound assessment of the inferior vena cava could guide fluid management in patients with …
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CLINICAL_TRIALS trial_result · 2024-06-07Clinical Trial Update: Effects of Fluid Therapy on Peripheral TIssse Perfusion During Sepsis/Septic Shock
This entry notes the completion of a clinical trial evaluating the effect of fluid therapy on peripheral tissue perfusion in septic shock or…
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CLINICAL_TRIALS trial_result · 2024-06-07Clinical Trial Update: MICU Recovery Clinic
A Wake Forest University Health Sciences study called MICU Recovery Clinic, focusing on critical illness and sepsis (including respiratory f…
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CLINICAL_TRIALS research · 2024-06-07Clinical Trial Update: Can we Improve Mortality Prediction in Patients With Sepsis in the Emergency Department
A completed clinical trial update investigating whether mortality prediction for sepsis patients in the emergency department can be improved…
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CLINICAL_TRIALS trial_result · 2024-06-05Clinical Trial Update: Combined Hemoperfusion and Therapeutic Plasma Exchange for Treatment of Patients With Septic Shock
A clinical trial evaluating the combination of hemoperfusion and therapeutic plasma exchange for septic shock has completed.
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Optic Nerve Sheath Diameter for Prediction of Sepsis Associated Encephalopathy
A completed clinical trial evaluating whether optic nerve sheath diameter can predict sepsis-associated encephalopathy in patients with seps…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia.
Clinical trial update describing the development of an ELISA assay to detect procalcitonin variants in patients with hyperprocalcitoninemia.
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CLINICAL_TRIALS trial_result · 2024-06-03Clinical Trial Update: (Revival) Study to Investigate the Efficacy and Safety of Alkaline Phosphatase in Patients With Sepsis-Associated AKI [Phase 3]
Phase 3 trial evaluating alkaline phosphatase for sepsis-associated acute kidney injury was terminated and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Esmolol in Sepsis Management:Evaluating Immunomodulatory Effects and Impact on Patient Outcomes [Phase 2]
This update reports the completion of a Phase 2 clinical trial evaluating esmolol for sepsis management, focusing on immunomodulatory effect…
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Hemodynamic Response to Angiotensin-II When Used as the Second Vasopressor Agent for Septic Shock [Phase 4]
An ongoing Phase 4 clinical trial evaluating angiotensin-II as a second vasopressor for septic shock, currently recruiting.
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CLINICAL_TRIALS research · 2024-05-23Clinical Trial Update: Emergency PWAS in Respiratory Infectious Disease
A University of Hong Kong-led clinical trial on emergency PWAS for respiratory infectious disease is currently recruiting, focusing on pneum…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Fecal Microbial Transplantation in Critically Ill Patients With Severe Infections. [NA]
A clinical trial evaluating fecal microbiota transplantation in critically ill patients with severe infections is currently recruiting in Sh…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Can Shock Indices Be Prognostic Indicators in Sepsis/Septic Shock?
A completed clinical study evaluated whether shock indices can serve as prognostic indicators in patients with sepsis and septic shock.
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Molecular Biomarkers for Sepsis
A University Hospital Basel study evaluating molecular biomarkers for sepsis, including severe community-acquired pneumonia, has been termin…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Urine Interleukin-37 as a Biomarker of Mortality Risk in Patients With Sepsis
A completed trial assessing whether urine interleukin-37 can predict mortality risk in sepsis patients. The study reports results on IL-37 a…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Insufficient Oxygenation in Septic Patients
This document reports the completion of a clinical trial investigating insufficient oxygenation in septic patients.
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CLINICAL_TRIALS research · 2024-05-03Clinical Trial Update: Longitudinal Evolution of Biomarkers of Dysautonomia and Inflammation During Sepsis in Children
A pediatric trial is investigating how biomarkers of dysautonomia and inflammation change over time in children with sepsis.
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FDA approval · 2024-05-01FDA Approved: PIPERACILLIN AND TAZOBACTAM — Supplemental Application (Civica, Inc.)
FDA approved a supplemental application for Civica, Inc. for Piperacillin and Tazobactam (piperacillin/tazobactam).
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: The Role of Salivary Alpha Amylase in Sepsis
The completed clinical trial investigates salivary alpha amylase in sepsis and reports results on its potential role in the condition.
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Prevalence Of Vitamin A Deficiency In Critically Ill Children With Sepsis And Its Association With Clinical Outcomes
This completed clinical trial from Benha University examined how common vitamin A deficiency is among critically ill children with sepsis an…
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CLINICAL_TRIALS trial_result · 2024-04-22Clinical Trial Update: Selective Antibiotics When Symptoms Develop Versus Universal Antibiotics for Preterm Neonates [Phase 3]
Phase 3 trial evaluating selective versus universal antibiotics for preterm neonates with sepsis risk factors; currently not yet recruiting.