Hyperparathyroidism
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CLINICAL_TRIALS trial_result · 2014-02-11Clinical Trial Update: ACHIEVE: Optimizing the Treatment of Secondary Hyperparathyroidism [Phase 4]
Amgen completed a Phase 4 clinical trial update aimed at optimizing treatment of secondary hyperparathyroidism.
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CLINICAL_TRIALS trial_result · 2014-01-22Clinical Trial Update: E.V.O.L.V.E. Trial™: EValuation Of Cinacalcet Hydrochloride (HCl) Therapy to Lower CardioVascular Events [Phase 3]
Phase 3 trial update for cinacalcet hydrochloride (E.V.O.L.V.E. Trial) assessing its impact on cardiovascular events in secondary hyperparat…
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CLINICAL_TRIALS trial_result · 2013-12-04Clinical Trial Update: Bone Biopsy Study For Dialysis Patients With Secondary Hyperparathyroidism of End Stage Renal Disease [Phase 2]
Phase 2 bone biopsy study in dialysis patients with secondary hyperparathyroidism; results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-11-13Clinical Trial Update: Cincalcet and Vascular Arterial Stiffness Among Peritoneal Dialysis Patients With Secondary Hyperparathyroidism [Phase 4]
Phase 4 clinical trial evaluating cinacalcet for effects on vascular arterial stiffness in peritoneal dialysis patients with secondary hyper…
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CLINICAL_TRIALS trial_result · 2013-11-11Clinical Trial Update: Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease [Phase 3]
A Phase 3 trial evaluating the effect of vitamin D3 supplementation on inflammation markers in high-risk cardiovascular patients with chroni…
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CLINICAL_TRIALS trial_result · 2013-10-16Clinical Trial Update: Effect of Vitamin D Treatment in Primary Hyperparathyroidism [Phase 2, Phase 3]
Phase 2 and Phase 3 trial results evaluating Vitamin D therapy in primary hyperparathyroidism have been completed, with results posted in 20…
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CLINICAL_TRIALS trial_result · 2013-08-26Clinical Trial Update: Near Infrared Fluorescent Imaging in Thyroid and Parathyroid Surgery With the Fluobeam(TM) System of Fluoptics [Phase 1]
Phase 1 trial evaluating near-infrared fluorescent imaging with the Fluobeam system to aid thyroid and parathyroid surgery in patients with …
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CLINICAL_TRIALS trial_result · 2013-08-13Clinical Trial Update: Study to Evaluate Safety of Vitamin D Receptor Activators in Patients Ages 0 to 16 With Chronic Kidney Disease Stage 5 Receiving Peritoneal Dialysis Within Current Clinical Practice
A pediatric trial evaluating the safety of vitamin D receptor activators in chronic kidney disease stage 5 patients on peritoneal dialysis w…
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CLINICAL_TRIALS trial_result · 2013-06-28Clinical Trial Update: OPG/Soluble RANKL (sRANKL) and Bone Mineral Density in Primary Hyperparathyroidism [NA]
A completed study examining the effects of osteoprotegerin (OPG) and soluble RANKL on bone mineral density in individuals with primary hyper…
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CLINICAL_TRIALS trial_result · 2013-06-07Clinical Trial Update: Short- and Long-Term Impact of Subtotal Parathyroidectomy on the Achievement of Bone and Mineral Parameters Recommended by Clinical Practice Guidelines in Dialysis Patients
A completed clinical trial assessing the short- and long-term impact of subtotal parathyroidectomy on bone and mineral parameters in dialysi…
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CLINICAL_TRIALS trial_result · 2013-06-06Clinical Trial Update: Comparison of Efficacy and Safety of Paricalcitol Injection With Maxacalcitol Injection in Adult Japanese Chronic Kidney Disease Subjects Receiving Hemodialysis With Secondary Hyperparathyroidism [Phase 3]
Phase 3 trial comparing paricalcitol injections with maxacalcitol injections in adult Japanese CKD patients on hemodialysis with secondary h…
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CLINICAL_TRIALS trial_result · 2013-05-23Clinical Trial Update: SENSOR: Study to Investigate Cinacalcet Treatment in Haemodialysis Patients With Secondary Hyperparathyroidism [Phase 3]
This document notes the completion of the Phase 3 SENSOR trial evaluating cinacalcet for secondary hyperparathyroidism in patients on haemod…
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: A Study to Assess the Efficacy and Safety of Twice-Daily Dose Regimens of an Oral Calcimimetic Agent AMG 073 (Cinacalcet) in Primary Hyperparathyroidism (PHPT) [Phase 2]
This completed Phase 2 trial evaluated the efficacy and safety of twice-daily cinacalcet (AMG 073) in patients with primary hyperparathyroid…
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: A Study of an Investigational Medication for the Treatment of Secondary Hyperparathyroidism in Dialysis Patients [Phase 3]
This entry reports the completion of a Phase 3 study evaluating an investigational medication for secondary hyperparathyroidism in patients …
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: A Study of an Investigational Medication for the Treatment of Secondary Hyperparathyroidism in Patients on Dialysis [Phase 3]
Phase 3 clinical trial of an investigational medication for secondary hyperparathyroidism in patients on dialysis has completed.
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: A Multicenter, Open-label Extension Study to Assess the Long-term Safety and Efficacy of an Oral Calcimimetic Agent AMG 073 (Cinacalcet) in Primary Hyperparathyroidism [Phase 2]
A multicenter, open-label extension study of cinacalcet (AMG 073) assesses long-term safety and efficacy in individuals with primary hyperpa…
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: Oral Paricalcitol in Kidney Transplant Recipients [NA]
A completed clinical trial evaluated oral paricalcitol in kidney transplant recipients. Results were posted in 2013.
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: Cinacalcet HCl in Chronic Kidney Disease Subjects With Secondary Hyperparathyroidism Not Receiving Dialysis [Phase 3]
A Phase 3 trial of cinacalcet HCl in chronic kidney disease patients with secondary hyperparathyroidism not on dialysis has completed.
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CLINICAL_TRIALS trial_result · 2013-05-08Clinical Trial Update: A Study of an Investigational Medication for Severe Primary Hyperparathyroidism or Parathyroid Cancer [Phase 4]
Amgen conducted a Phase 4 trial of an investigational medication for severe primary hyperparathyroidism and parathyroid neoplasms; the study…
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CLINICAL_TRIALS trial_result · 2013-03-07Clinical Trial Update: Paricalcitol Oral Therapy in Predialysis CKD Patients. The Greek Experience
This update reports results from a completed clinical trial evaluating oral paricalcitol for predialysis chronic kidney disease patients, in…
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CLINICAL_TRIALS trial_result · 2013-02-22Clinical Trial Update: Paricalcitol in Reducing Parathyroid Hormone Levels and Ameliorating Markers of Bone Remodelling in Renal Transplant Recipients With Secondary Hyperparathyroidism [Phase 2]
Phase 2 trial assessing paricalcitol's ability to lower parathyroid hormone levels and improve bone remodeling markers in renal transplant r…
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CLINICAL_TRIALS trial_result · 2013-01-28Clinical Trial Update: Evaluation of Non Specific Symptoms and Quality of Life Before and After Surgery for Mild Primary Hyperparathyroidism
This clinical trial update reports on non-specific symptoms and quality of life before and after surgery for mild primary hyperparathyroidis…
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CLINICAL_TRIALS trial_result · 2012-12-21Clinical Trial Update: Observational Study to Evaluate the Time to Achieving the Maintenance Dose of Zemplar® (Paricalcitol Injection) in the Treatment of Patients Suffering From End-stage Renal Disease and Severe Over-reactivity of the Parathyroid Glands
This completed observational study evaluated the time to achieve the maintenance dose of paricalcitol (Zemplar) in patients with end-stage r…
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CLINICAL_TRIALS trial_result · 2012-12-06Clinical Trial Update: Safety and Efficacy Study of Paricalcitol Versus Calcitriol in the Treatment of Secondary Hyperparathyroidism [NA]
A completed clinical trial comparing paricalcitol versus calcitriol for safety and efficacy in treating secondary hyperparathyroidism in pat…
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CLINICAL_TRIALS trial_result · 2012-12-04Clinical Trial Update: Morbidity Related to Secondary Hyperparathyroidism After Renal Transplantation
A completed clinical trial evaluating morbidity related to secondary hyperparathyroidism in kidney transplant recipients.