Sciatica
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CLINICAL_TRIALS research · 2018-03-19Clinical Trial Update: Clinical Trial to Evaluate the Safety and Analgesic Efficacy of VVZ-149 in Lumbar Radiculopathy (Sciatica) [Phase 1]
This document details a completed Phase 1 trial evaluating the safety and analgesic efficacy of VVZ-149 in lumbar radiculopathy (sciatica).
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CLINICAL_TRIALS trial_result · 2018-03-05Clinical Trial Update: [18F]FTC-146 PET/MRI in Healthy Volunteers and in CRPS and Sciatica [EARLY_Phase 1]
An early-phase study evaluating the PET tracer [18F]FTC-146 for PET/MRI in healthy volunteers and in Complex Regional Pain Syndrome and Scia…
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CLINICAL_TRIALS trial_result · 2017-12-05Clinical Trial Update: Outcome of Surgery for Sciatica - a Comparison of Data From Three National Quality Registries
A clinical trial update comparing surgical outcomes for sciatic symptoms due to intervertebral disc displacement using data from three natio…
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CLINICAL_TRIALS research · 2017-08-07Clinical Trial Update: A Comparative Effectiveness Randomised Placebo Controlled Pilot Trial of the Management of Acute Lumbar Radicular Pain [Phase 2]
A Phase 2 pilot randomized, placebo-controlled trial evaluating management strategies for acute lumbar radicular pain (acute sciatica).
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Pain Treatment for Sciatica [Phase 2]
A Phase 2 clinical trial update shows the pain treatment study for radiculopathy and sciatica has completed.
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: A Study of the Pharmacokinetics, Safety, and Preliminary Efficacy of MDT-15 in Subjects With Lumbosacral Radiculopathy [Phase 2]
Phase 2 trial evaluating the pharmacokinetics, safety, and preliminary efficacy of MDT-15 in subjects with lumbosacral radiculopathy (sciati…
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Steroids Versus Gabapentin [NA]
A completed clinical trial comparing a steroid against gabapentin for sciatic-related radiculopathy; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2016-11-10Clinical Trial Update: Physiotherapy for Sciatica; Is Earlier Better? [Phase 3]
Phase 3 clinical trial completed to evaluate timing of physiotherapy for sciatica and related low back pain.
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CLINICAL_TRIALS research · 2016-11-03Clinical Trial Update: Chiropractic Spinal Manipulative Therapy for Acute Sciatica Secondary to Lumbar Disc Herniation [NA]
The document provides an update on a clinical trial evaluating chiropractic spinal manipulative therapy for acute sciatica due to lumbar dis…
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CLINICAL_TRIALS research · 2016-10-17Clinical Trial Update: Transforaminal Epidural Steroid Injection With Pulsed Radiofrequency for Chronic Lumbosacral Radicular Pain Management [Phase 4]
Clinical trial update describing a Phase 4 study of transforaminal epidural steroid injections with pulsed radiofrequency for chronic lumbos…
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CLINICAL_TRIALS trial_result · 2016-07-21Clinical Trial Update: Study to Evaluate the Safety and Efficacy of Placulumab (CEP-37247) Administered by the Transforaminal Epidural Route for the Treatment of Patients With Lumbosacral Radicular Pain Associated With Disk Herniation [Phase 1, Phase 2]
The study reports on a completed Phase 1/2 trial evaluating safety and efficacy of Placulumab (CEP-37247) delivered by the transforaminal ep…
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CLINICAL_TRIALS trial_result · 2016-07-15Clinical Trial Update: Comparison of Intravenous Ibuprofen and Paracetamol in Patients With Sciatica Presented to the Emergency Department [Phase 4]
Phase 4 trial comparing intravenous ibuprofen to paracetamol for sciatic pain in emergency department patients. The study status is listed a…
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CLINICAL_TRIALS trial_result · 2016-06-02Clinical Trial Update: The Effectiveness of Neurodynamic Techniques in Patients With Nerve-Related Leg Pain [NA]
This is a completed clinical trial assessing the effectiveness of neurodynamic techniques for nerve-related leg pain. The study was sponsore…
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CLINICAL_TRIALS research · 2016-05-12Clinical Trial Update: "The Lived Experience of Investigations for Sciatica"
An update on the ongoing clinical trial NCT02512081 studying the lived experiences of individuals undergoing investigations for sciatica, sp…
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Efficacy of Acupuncture for Discogenic Sciatica [NA]
This document reports a clinical trial evaluating acupuncture for discogenic sciatica, with the current status listed as UNKNOWN.
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CLINICAL_TRIALS trial_result · 2016-03-24Clinical Trial Update: Safety and Efficacy of Nonsteroidal Antiinflammatory (NSAI)Drug and Glucocorticoids in Acute Sciatica [Phase 4]
This update reports on a Phase 4 trial evaluating the safety and efficacy of nonsteroidal anti-inflammatory drugs and glucocorticoids for ac…
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CLINICAL_TRIALS trial_result · 2015-09-10Clinical Trial Update: BG00010 (Neublastin) Phase 2 Multiple Dose Adaptive Design in Participants With Painful Lumbar Radiculopathy [Phase 2]
Biogen's BG00010 (Neublastin) completed a Phase 2 multiple-dose adaptive design trial in participants with painful lumbar radiculopathy. The…
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CLINICAL_TRIALS research · 2015-07-22Clinical Trial Update: IV Paracetamol vs IV Morphine vs Placebo in Sciatalgia [Phase 4]
Phase 4 clinical trial comparing intravenous paracetamol, intravenous morphine, and placebo for sciatic pain; current status is unknown.
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CLINICAL_TRIALS trial_result · 2015-06-03Clinical Trial Update: Caudal Corticosteroid vs. Dextrose Injection for Lumbosacral Radicular Pain. [Phase 2]
Phase 2 clinical trial comparing caudal corticosteroid injection with dextrose injection for lumbosacral radicular pain; the current status …
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CLINICAL_TRIALS trial_result · 2015-05-27Clinical Trial Update: Caudal Epidural Steroid Injections for Low Back Pain/Sciatic Lumbar Pain [Phase 4]
A Phase 4 clinical trial evaluating caudal epidural steroid injections for low back pain and sciatica has completed.
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CLINICAL_TRIALS trial_result · 2015-04-28Clinical Trial Update: Effectiveness of Oral Prednisone in Improving Physical Functioning and Decreasing Pain in People With Sciatica [Phase 2]
This Phase 2 trial evaluated the effectiveness of oral prednisone for improving physical functioning and reducing pain in people with sciati…
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CLINICAL_TRIALS withdrawal · 2015-03-17Clinical Trial Update: Trial Comparing Duration of Analgesia After Popliteal Fossa Sciatiac Nerve Block With Ropivacaine 0.5% When Combined With Placebo, Dexamethasone 4mg or Dexamethasone 8 mg [NA]
The clinical trial NCT01641419, comparing duration of analgesia after popliteal fossa sciatic nerve block with ropivacaine 0.5% plus placebo…
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CLINICAL_TRIALS trial_result · 2014-10-28Clinical Trial Update: Evaluate the Safety, Tolerability and Pharmacokinetics of BG00010 (Neublastin) Administered to Sciatica Participants [Phase 1]
A Phase 1 study assessed safety, tolerability, and pharmacokinetics of BG00010 (Neublastin) in participants with sciatica; the trial status …
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CLINICAL_TRIALS trial_result · 2014-09-09Clinical Trial Update: Study of the Safety, Tolerability, Pharmacokinetics and Safety of BG00010 (Neublastin) in Subjects With Sciatica. [Phase 1]
A Phase 1 study evaluated safety, tolerability, and pharmacokinetics of BG00010 (Neublastin) in subjects with sciatica and has completed.
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CLINICAL_TRIALS trial_result · 2014-05-23Clinical Trial Update: Herniectomy Versus Herniectomy With a Spinal Stabilization System for the Treatment of Complex Disc Disease [Phase 4]
Phase 4 trial comparing Herniectomy alone to Herniectomy with a Spinal Stabilization System for complex disc disease completed; results post…