Schizophrenia
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CLINICAL_TRIALS trial_result · 2016-02-08Clinical Trial Update: Safety and Tolerability of Aripiprazole in Adolescents With Schizophrenia or Children and Adolescents With Bipolar I Disorder, Manic or Mixed Episode With or Without Psychotic Features. [Phase 3]
A Phase 3 trial evaluating the safety and tolerability of aripiprazole in adolescents with schizophrenia and in children/adolescents with Bi…
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CLINICAL_TRIALS trial_result · 2016-02-08Clinical Trial Update: Psychosis: Early Detection, Intervention and Prevention [NA]
Clinical trial update from MaineHealth reports completion and posted results for a study on psychosis focusing on early detection, intervent…
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CLINICAL_TRIALS trial_result · 2016-02-05Clinical Trial Update: Parallel Effects of Schizophrenia and N-methyl-D-aspartate (NMDA) Antagonism [Phase 1]
Phase 1 Yale trial examined the effects of NMDA receptor antagonism in schizophrenia, and the study has completed.
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CLINICAL_TRIALS withdrawal · 2016-02-05Clinical Trial Update: NRX-1074 in Early Course Schizophrenia [Phase 2]
A Phase 2 trial of NRX-1074 for early course schizophrenia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-02-05Clinical Trial Update: Nicotinic Receptors and Schizophrenia [Phase 1]
Phase 1 trial evaluating nicotinic receptor targets in schizophrenia. Results have been posted.
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CLINICAL_TRIALS trial_result · 2016-02-04Clinical Trial Update: PET Trial to Assess the Receptor Occupancy of Brexpiprazole in Adult Subjects With Schizophrenia [Phase 1]
Phase 1 PET imaging study to assess receptor occupancy of brexpiprazole in adults with schizophrenia; completed with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Reducing Internalized Stigma in People With Serious Mental Illness [Phase 2]
Phase 2 trial update evaluating an intervention to reduce internalized stigma in people with serious mental illness, including schizophrenia…
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CLINICAL_TRIALS research · 2016-01-28Clinical Trial Update: Clinical Trial of Integrated Treatment Versus Standard Treatment in First Episode Psychosis [NA]
Clinical trial update comparing integrated treatment with standard treatment for first-episode psychosis, sponsored by Bispebjerg Hospital.
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CLINICAL_TRIALS research · 2016-01-27Clinical Trial Update: Intermittent Theta Burst Stimulation (iTBS) for the Treatment of Negative Symptoms in Schizophrenia [NA]
Clinical trial update indicating completion of a study evaluating intermittent theta burst stimulation for negative symptoms in schizophreni…
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FDA approval · 2016-01-27FDA Approved: OLANZAPINE — Original Application (Upsher-Smith Laboratories, LLC)
Approval of a generic olanzapine product under an Original Application (ANDA) by Upsher-Smith Laboratories, LLC.
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CLINICAL_TRIALS trial_result · 2016-01-26Clinical Trial Update: A Study of Paliperidone Palmitate in Patients With Schizophrenia Previously Unsuccessfully Treated by Oral Antipsychotics [Phase 4]
Phase 4 trial evaluating paliperidone palmitate in schizophrenia patients previously unsuccessfully treated with oral antipsychotics has com…
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CLINICAL_TRIALS trial_result · 2016-01-22Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of ALKS 9072 (Also Known as Aripiprazole Lauroxil, ALKS 9070, or ARISTADA) in Subjects With Schizophrenia [Phase 3]
Phase 3 trial results evaluate the efficacy and safety of ALKS 9072 (aripiprazole lauroxil; ARISTADA) in adults with schizophrenia; results …
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CLINICAL_TRIALS trial_result · 2016-01-22Clinical Trial Update: Life Goals Collaborative Care to Improve Health Outcomes in Mental Disorders [NA]
The Life Goals Collaborative Care trial evaluating health outcomes in mental disorders has completed, with results posted on Jan 22, 2016.
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CLINICAL_TRIALS trial_result · 2016-01-22Clinical Trial Update: Neuropsychobiological Correlates of Sex-steroid Hormone Manipulation in Healthy Women: a Risk Model for Depression [NA]
This entry notes the completion of a clinical trial investigating the neuropsychobiological correlates of sex-steroid hormone manipulation i…
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FDA approval · 2016-01-22FDA Approved: CLOZAPINE — Supplemental Application (Mylan Pharmaceuticals Inc.)
The FDA approved Mylan Pharmaceuticals' supplemental application for clozapine (generic), enabling a generic version under ANDA201824.
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CLINICAL_TRIALS trial_result · 2016-01-15Clinical Trial Update: Treatment With Acamprosate in Patients With Schizophrenia and Comorbid Alcoholism [Phase 3]
Phase 3 clinical trial evaluating acamprosate in patients with schizophrenia and comorbid alcoholism has completed with results posted.
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CLINICAL_TRIALS research · 2016-01-12Clinical Trial Update: Implementation of Illness Management and Recovery in Mental Health Services [NA]
A clinical trial evaluating the implementation of Illness Management and Recovery in mental health services has completed, focusing on patie…
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CLINICAL_TRIALS trial_result · 2016-01-12Clinical Trial Update: Social Cognitive Training for Psychosis: Treatment Development [Phase 1]
Phase 1 study of Social Cognitive Training for Psychosis for schizophrenia/psychosis has been completed. The results will inform next steps …
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CLINICAL_TRIALS trial_result · 2016-01-12Clinical Trial Update: Treatment Development Targeting Severe and Persistent Negative Symptoms [NA]
This update describes a completed clinical trial from UT Health San Antonio focused on developing treatments for severe, persistent negative…
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CLINICAL_TRIALS trial_result · 2016-01-11Clinical Trial Update: SPECT Investigation Of The NMDA Receptor System In Healthy Volunteers And Patients With Schizophrenia [Phase 1]
Phase 1 SPECT study investigating the NMDA receptor system in healthy volunteers and patients with schizophrenia; the trial has been termina…
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CLINICAL_TRIALS trial_result · 2016-01-08Clinical Trial Update: Lurasidone Low-Dose - High-Dose Study Study [Phase 3]
Phase 3 trial comparing low-dose versus high-dose lurasidone in schizophrenia completed; results were posted in January 2016.
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CLINICAL_TRIALS research · 2016-01-08Clinical Trial Update: The Role of miR-30 Family Dysregulation in Response to Antipsychotic Treatment [Phase 1, Phase 2]
This document reports a Phase 1/2 clinical trial investigating the role of miR-30 family dysregulation in response to antipsychotic treatmen…
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CLINICAL_TRIALS trial_result · 2016-01-08Clinical Trial Update: The Influence of Vitamin D on Atypical Antipsychotic-induced Weight Gain
A completed trial from Creighton University investigated whether vitamin D supplementation influences weight gain associated with atypical a…
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CLINICAL_TRIALS trial_result · 2016-01-07Clinical Trial Update: Genetic Research in Schizophrenia Using DNA Markers and Clinical Phenotypes
This clinical trial update describes a completed study on genetic research in schizophrenia using DNA markers and clinical phenotypes, with …
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FDA approval · 2016-01-04FDA Approved: QUETIAPINE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
The FDA approved a supplemental application for a generic quetiapine product from Teva Pharmaceuticals USA, Inc.