Schizophrenia
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: An Extension Study to a Clinical Study That Will Continue to Evaluate the Effectiveness and Safety of SEP-363856 in People With Schizophrenia That Switch to SEP-363856 From Their From Their Current Antipsychotic Medication [Phase 3]
This document reports results from an extension Phase 3 study of SEP-363856 in schizophrenia. It examines effectiveness and safety when pati…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Clinical Trial of Iclepertin Effect on Cognition and Functional Capacity in Schizophrenia (CONNEX-1) [Phase 3]
Phase 3 CONNEX-1 trial evaluated Iclepertin's impact on cognition and functional capacity in schizophrenia. The study is completed and resul…
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CLINICAL_TRIALS trial_result · 2025-10-28Clinical Trial Update: A Trial of 15 and 30 mg Doses of CVL-231 (Emraclidine) in Participants With Schizophrenia [Phase 2]
AbbVie completed a Phase 2 trial evaluating 15 mg and 30 mg doses of emraclidine (CVL-231) in schizophrenia, with the results posted.
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CLINICAL_TRIALS trial_result · 2025-10-27Clinical Trial Update: Open-Label, Flexible-dose Study to Evaluate the Long-Term Safety and Tolerability of Cariprazine in the Treatment of Pediatric Participants With Schizophrenia, Bipolar I Disorder, or Autism Spectrum Disorder [Phase 3]
Open-label, flexible-dose study to evaluate the long-term safety and tolerability of cariprazine in pediatric participants with schizophreni…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: Randomized, Double-blinded, Placebo-controlled, Evaluating the Treatment With LB-102 in Patients With Acute Schizophrenia [Phase 2]
A Phase 2 randomized, double-blind, placebo-controlled trial evaluating LB-102 for acute schizophrenia has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2025-10-20Clinical Trial Update: Study to Assess Adverse Events and Change in Disease Activity of Oral Cariprazine Capsules in Adult Participants With Schizophrenia [Phase 3]
Phase 3 trial evaluating adverse events and changes in disease activity with oral cariprazine in adults with schizophrenia has been terminat…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Study of Two Digital Therapeutics for the Treatment of Experiential Negative Symptoms of Schizophrenia [Phase 3]
Phase 3 clinical trial completion update for two digital therapeutics targeting experiential negative symptoms in schizophrenia.
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: An Extension Study of a Second Course of a Digital Therapeutic for the Treatment of Experiential Negative Symptoms of Schizophrenia [Phase 3]
Phase 3 extension study update for a digital therapeutic by Click Therapeutics addressing experiential negative symptoms in schizophrenia; t…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: A Translational and Neurocomputational Evaluation of a Dopamine Receptor 1 Partial Agonist for Schizophrenia [Phase 2]
Phase 2 translational and neurocomputational evaluation of a dopamine D1 receptor partial agonist for schizophrenia has completed, with resu…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Mobile Self-Tracking of Mental Health [NA]
This clinical trial update notes the completion and posting of results for a mobile self-tracking study addressing mental health conditions …
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Study of a Novel Antipsychotic ITI-007 in Schizophrenia [Phase 2]
Phase 2 clinical trial update for ITI-007 (lumateperone) in schizophrenia; the study is completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Efficacy of Social Cognition Training in Schizophrenia [NA]
The update reports results from a completed trial evaluating the efficacy of social cognition training in individuals with schizophrenia; re…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Remote State Representation in Early Psychosis [EARLY_Phase 1]
Final update indicating the EARLY_PHASE1 clinical trial on remote state representation in early psychosis has completed.
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: A Trial to Assess the Antipsychotic Efficacy of ITI-007 [Phase 3]
A Phase 3 trial evaluating the antipsychotic ITI-007 for schizophrenia has completed. Results have been posted.
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: A Trial to Assess the Antipsychotic Efficacy of ITI-007 Over 6 Weeks of Treatment [Phase 3]
A Phase 3 trial evaluating the antipsychotic ITI-007 for schizophrenia has completed and posted results after 6 weeks of treatment.
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Estimating and Reducing the Cardiovascular Risk of Patients With Schizophrenia Drugs From Lipid Measures and Ischemic Electrocardiographic Changes [Phase 3]
Phase 3 clinical trial update evaluating methods to estimate and reduce cardiovascular risk in patients with schizophrenia using lipid measu…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Culture and Well-being: Art as Prescription Therapy ("Art on Prescription") [NA]
Completed clinical trial evaluating art-based prescription therapy for several mental health conditions, including anxiety disorders, depres…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Video as a Tool to Improve Insight in Schizophrenia [NA]
This entry notes the completion of a clinical trial evaluating the use of video to improve insight in people with schizophrenia or schizoaff…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Schizophrenia Treatment With Photoneuromodulation [Phase 2]
A Phase 2 clinical trial evaluating photoneuromodulation for schizophrenia has completed.
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CLINICAL_TRIALS trial_result · 2025-09-26Clinical Trial Update: The Effect of a Six Week Intensified Pharmacological Treatment for Schizophrenia Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment. [Phase 4]
A Phase 4 clinical trial evaluating six-week intensified pharmacological treatment versus treatment as usual in schizophrenia patients who h…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Behavioral Impact and Neural Correlates of Network-based Brain Stimulation in Schizophrenia [NA]
This clinical trial update reports on the behavioral effects and neural correlates of network-based brain stimulation in individuals with sc…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: Assessment and Treatment for Chronic Pain in Veterans With Serious Mental Illness [NA]
This clinical trial update notes the completion of a study evaluating assessment and treatment approaches for chronic pain in veterans with …
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: State Representation in Early Psychosis
This ClinicalTrials.gov entry describes a University of Minnesota trial on state representation in early psychosis that has completed.
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Pharmacokinetic Study of VHX-896 and Iloperidone Tablets Under Steady-State Conditions [Phase 1]
Phase 1 pharmacokinetic study evaluating VHX-896 in combination with iloperidone tablets under steady-state conditions; the study has comple…
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CLINICAL_TRIALS trial_result · 2025-09-19Clinical Trial Update: Comparison of the Effects of Aerobic Exercise and Computerized Cognitive Stimulation in Patients With Schizophrenia - A Randomized Controlled Trial [NA]
This randomized controlled trial compared the effects of aerobic exercise and computerized cognitive stimulation in patients with schizophre…