Schizophrenia
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CLINICAL_TRIALS trial_result · 2014-05-30Clinical Trial Update: Investigation of the Safety, Tolerability and Potential Therapeutic Effects of JNJ-40411813 in Patients With Schizophrenia [Phase 2]
Phase 2 trial of JNJ-40411813 in schizophrenia has completed, examining safety, tolerability and potential therapeutic effects.
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CLINICAL_TRIALS trial_result · 2014-05-29Clinical Trial Update: Adjunctive SPD489 to Antipsychotic Medication in Clinically Stable Adults With Persistent Predominant Negative Symptoms of Schizophrenia [Phase 3]
Phase 3 trial of adjunctive SPD489 to antipsychotic therapy in adults with persistent prominent negative symptoms of schizophrenia was termi…
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CLINICAL_TRIALS trial_result · 2014-05-29Clinical Trial Update: SPD489 Low Dose and High Dose Ranges When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia [Phase 3]
Phase 3 trial evaluating SPD489 at low and high doses added to stable antipsychotic regimens in adults with negative symptoms of schizophren…
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CLINICAL_TRIALS trial_result · 2014-05-29Clinical Trial Update: Long-term Safety of SPD489 When Added to Stable Doses of Antipsychotic Medications in Clinically Stable Adults With Negative Symptoms of Schizophrenia [Phase 3]
Phase 3 trial updating long-term safety of SPD489 added to stable antipsychotics in adults with schizophrenia and negative symptoms; study t…
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CLINICAL_TRIALS trial_result · 2014-05-28Clinical Trial Update: Efficacy Study Exploring the Effects on Cognition of Sertindole Versus Comparator in Patients With Schizophrenia [Phase 3]
A Phase 3 efficacy trial comparing sertindole to a comparator in people with schizophrenia to assess cognitive effects has been completed.
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CLINICAL_TRIALS trial_result · 2014-05-28Clinical Trial Update: A Safety and Pharmacokinetic Study of Paliperidone Palmitate in Patients With Schizophrenia [Phase 1]
A Phase 1 safety and pharmacokinetic study evaluated paliperidone palmitate in patients with schizophrenia, describing its PK profile and to…
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CLINICAL_TRIALS trial_result · 2014-05-26Clinical Trial Update: Once-Daily Asenapine for Schizophrenia [Phase 4]
A Phase 4 clinical trial update on once-daily asenapine for schizophrenia, with the study completed and results posted.
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CLINICAL_TRIALS trial_result · 2014-05-23Clinical Trial Update: Medical Chart Review of Patients on Long-term Treatment With Long-acting Injectable Risperidone
A clinical trial update reports on the long-term use of long-acting injectable risperidone in patients with schizophrenia or schizoaffective…
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CLINICAL_TRIALS trial_result · 2014-05-22Clinical Trial Update: Ethyl-EPA Treatment of Prodromal Patients [Phase 2, Phase 3]
Phase 2/3 trial of Ethyl-EPA for prodromal schizophrenia has completed.
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CLINICAL_TRIALS trial_result · 2014-05-22Clinical Trial Update: Shiatsu Adjuvant Therapy For Schizophrenia [NA]
This entry notes the completion of a clinical trial evaluating shiatsu adjuvant therapy for schizophrenia conducted by Herzog Hospital.
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CLINICAL_TRIALS trial_result · 2014-05-21Clinical Trial Update: Characterization of Intramuscular Injections of Risperidone 4 Week Long-acting Injectable (LAI) Formulation in the Buttock of Patients With Schizophrenia [Phase 1]
Phase 1 study characterizing intramuscular four-week long-acting injectable risperidone injections in the buttock of patients with schizophr…
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CLINICAL_TRIALS trial_result · 2014-05-20Clinical Trial Update: The Efficacy and Safety of Quetiapine XR in Patients With Schizophrenia Switched From Other Antipsychotics [Phase 3]
A Phase 3 trial update evaluating the efficacy and safety of quetiapine XR in schizophrenia patients who were switched from other antipsycho…
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CLINICAL_TRIALS trial_result · 2014-05-14Clinical Trial Update: Efficacy and Safety of A-prexa Compared to Zyprexa in Patients With Schizophrenia [Phase 4]
A Phase 4 trial evaluated the efficacy and safety of A-prexa compared with Zyprexa (olanzapine) in patients with schizophrenia-spectrum diso…
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CLINICAL_TRIALS trial_result · 2014-05-08Clinical Trial Update: A Follow-Up Study of Schizophrenic Participants Following Treatment Discontinuation After Remission From a First Psychotic Episode [Phase 4]
Phase 4 follow-up study in schizophrenia patients who achieved remission after a first psychotic episode, evaluating outcomes after disconti…
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CLINICAL_TRIALS trial_result · 2014-05-07Clinical Trial Update: Individually Based Psychosocial Rehabilitation for Older People With Serious Mental Illness (SMI) [Phase 1]
Phase 1 completion of a trial evaluating individually based psychosocial rehabilitation for older adults with serious mental illness, includ…
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CLINICAL_TRIALS trial_result · 2014-05-02Clinical Trial Update: Does Acute Oxytocin Administration Enhance Social Cognition in Individuals With Schizophrenia? [NA]
A completed clinical trial investigated whether single-dose oxytocin administration improves social cognition in individuals with schizophre…
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CLINICAL_TRIALS trial_result · 2014-04-29Clinical Trial Update: Improving Medication Adherence Among People With Schizophrenia Through the Use of 2-way Pagers [NA]
Completed clinical trial evaluated the use of two-way pagers to improve medication adherence in people with schizophrenia; results were post…
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CLINICAL_TRIALS trial_result · 2014-04-28Clinical Trial Update: Effects of Pravastatin on Cholesterol, Inflammation and Cognition in Schizophrenia [Phase 4]
Phase 4 clinical trial explored the effects of pravastatin on cholesterol, inflammation, and cognition in individuals with schizophrenia and…
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CLINICAL_TRIALS trial_result · 2014-04-28Clinical Trial Update: INVISION - An Observational Study to Explore Effectiveness, Tolerability and Safety of Paliperidone ER in Patients With Schizophrenia
An observational study evaluating the effectiveness, tolerability, and safety of paliperidone extended-release in adults with schizophrenia …
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CLINICAL_TRIALS trial_result · 2014-04-25Clinical Trial Update: Safety and Cognitive Function Study of EVP-6124 in Patients With Schizophrenia [Phase 2]
This update summarizes the completion of a Phase 2 safety and cognitive function study of EVP-6124 in patients with schizophrenia. The trial…
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CLINICAL_TRIALS trial_result · 2014-04-17Clinical Trial Update: A 4-week, Randomized, Rater-blinded, Parallel Study to Evaluate Quetiapine in Improving Sleep Quality of Schizophrenia [NA]
A 4-week randomized, rater-blinded study assessed quetiapine for improving sleep quality in individuals with schizophrenia; results were pos…
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CLINICAL_TRIALS trial_result · 2014-04-16Clinical Trial Update: A Pilot Trial of Acute N-Acetylcysteine Effects on Working Memory and Other Cognitive Functions in Schizophrenia [NA]
A Yale-sponsored pilot trial evaluated the acute effects of N-acetylcysteine on working memory and other cognitive functions in schizophreni…
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CLINICAL_TRIALS trial_result · 2014-04-10Clinical Trial Update: Pragmatic RCT Comparing Aripiprazole, Olanzapine and Haloperidol in the Treatment of Schizophrenia [Phase 4]
A Phase 4 pragmatic randomized trial comparing aripiprazole, olanzapine, and haloperidol for schizophrenia has completed.
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CLINICAL_TRIALS trial_result · 2014-04-09Clinical Trial Update: Comparison of the Effects of Aripiprazole and Risperidone on the Pattern of Brain Activation in Schizophrenic Patients [Phase 4]
Phase 4 clinical trial comparing aripiprazole and risperidone on brain activation patterns in patients with schizophrenia, with results post…
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CLINICAL_TRIALS trial_result · 2014-04-09Clinical Trial Update: Schizophrenia Treatment Adherence Investigation (STAI)
This is a completed clinical trial update for the STAI schizophrenia treatment adherence study sponsored by Janssen-Cilag Pty Ltd, evaluatin…