Schizophrenia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: An Efficacy, Safety And Tolerability Study of Flexibly Dosed Paliperidone Extended Release (ER) in Participants With Schizophrenia [Phase 3]
A Phase 3 study evaluating the efficacy, safety and tolerability of flexibly dosed paliperidone extended release (ER) in participants with s…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study of Transition to the Paliperidone Palmitate 3-Month Formulation In Participants With Schizophrenia Previously Stabilized on the Paliperidone Palmitate 1-Month Formulation [Phase 3]
A completed Phase 3 study evaluated transitioning schizophrenia patients stabilized on paliperidone palmitate 1-month to the 3-month formula…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study to Observe the Safety and Tolerability of Paliperidone Palmitate (Invega Sustenna) in Korean Schizophrenic Patients
A completed study assessing the safety and tolerability of paliperidone palmitate (Invega Sustenna) in Korean patients with schizophrenia.
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Survey to Collect Treatment Experience Feedback From Patients, Physicians, Nurses and Carers After Switching to Paliperidone Palmitate 3-monthly
A completed study collecting feedback from patients, physicians, nurses and carers after switching to paliperidone palmitate every three mon…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study to Analyze the Impact of Treatment With Paliperidone Palmitate on Clinical Outcomes and Hospital Resource Utilization in Adult Participants With Schizophrenia in Portugal
A completed study in Portugal evaluating how paliperidone palmitate affects clinical outcomes and hospital resource use in adults with schiz…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study to Assess the Treatment of Schizophrenia With Paliperidone Palmitate in Rwandan Healthcare Settings [Phase 4]
Phase 4 study evaluating paliperidone palmitate for schizophrenia in Rwanda has completed.
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study for Schizophrenia Relapse Prediction
A Janssen-sponsored clinical trial evaluating relapse prediction in schizophrenia has completed.
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study to Evaluate the Ability of Conducting a Study of Oral Risperidone Followed by Paliperidone Palmitate in Rwandan Healthcare Facilities [Phase 4]
A Phase 4 clinical trial sponsored by Janssen evaluated sequential use of oral risperidone followed by paliperidone palmitate in Rwandan hea…
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CLINICAL_TRIALS trial_result · 2025-04-25Clinical Trial Update: Predictors of Functional Remission in Discharged Patients With Schizophrenia After Long-term Drug Discontinuation
This clinical trial update analyzes predictors of functional remission in patients with schizophrenia who were discharged after long-term di…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: The Effect of a Mindfulness-Based Self-Compassion Program on Care Burden, Life Satisfaction, and Coping Levels of Caregivers of Individuals With Schizophrenia [NA]
A completed clinical trial evaluated a mindfulness-based self-compassion program for reducing caregiver burden and improving life satisfacti…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: A Study To Evaluate The Effect Of A Supratherapeutic Dose Of MK-8189 On The QTc Interval In Participants With Schizophrenia (MK-8189-019) [Phase 1]
Phase 1 trial evaluating the impact of a supratherapeutic dose of MK-8189 on the QTc interval in participants with schizophrenia; results ha…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Effects of Low-dose Levetiracetam on Clinical Symptoms, Cognition and Hippocampal Hyperactivity in Schizophrenia [NA]
A completed clinical trial evaluated the effects of low-dose levetiracetam on clinical symptoms, cognition, and hippocampal activity in schi…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: Safety and Efficacy of Brexpiprazole in the Treatment of Schizophrenia [Phase 3]
Phase 3 clinical trial evaluating the safety and efficacy of brexpiprazole for schizophrenia has completed, potentially informing next regul…
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CLINICAL_TRIALS trial_result · 2025-04-18Clinical Trial Update: TMS Enhancement of Visual Plasticity in Schizophrenia [NA]
This clinical trial evaluated transcranial magnetic stimulation to enhance visual plasticity in schizophrenia; the study was terminated and …
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CLINICAL_TRIALS trial_result · 2025-04-15Clinical Trial Update: Effects of Intranasal Insulin on Neuroimaging Markers and Cognition in Patients With Psychotic Disorders [Phase 2]
Phase 2 clinical trial evaluating the effects of intranasal insulin on neuroimaging markers and cognition in patients with psychotic disorde…
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CLINICAL_TRIALS trial_result · 2025-04-08Clinical Trial Update: Sequential Multiple-Assignment Randomized Trials to Compare Antipsychotic Treatments(SMART-CAT) [Phase 3]
A Phase 3 SMART design trial (SMART-CAT) evaluating sequences of antipsychotic treatments for schizophrenia has completed.
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: PET Imaging Study of α7 and α4β2-nAChR in Schizophrenia [Phase 1]
A Phase 1 PET imaging trial evaluating α7 and α4β2-nAChR in schizophrenia was terminated; no results are reported.
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Study to Assess Safety and Effectiveness of Slowly Increasing Dose and Food Effect of KarXT in Participants With Schizophrenia [Phase 3]
Phase 3 trial evaluating the KarXT fixed-dose combination (xanomeline-trospium) for schizophrenia has completed.
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: Effects of Buspirone Combined With Clozapine [EARLY_Phase 1]
This update notes the completion of an early-phase Phase 1 trial evaluating the combination of buspirone with clozapine for schizophrenia.
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: Efficacy and Safety of Pimavanserin as Adjunctive Treatment for the Negative Symptoms of Schizophrenia [Phase 3]
A Phase 3 trial evaluating pimavanserin as an adjunctive treatment for the negative symptoms of schizophrenia has completed; results on effi…
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: A Study to Assess Efficacy and Safety of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia [Phase 3]
Phase 3 study investigating adjunctive KarXT for inadequately controlled schizophrenia symptoms has completed.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Metabolic and Clinical Effect of Alpha-lipoic Acid Administration in Schizophrenic Subjects [NA]
A completed clinical trial evaluating the metabolic and cardiac effects of alpha-lipoic acid in people with schizophrenia; results were post…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of Co-Administration of Roluperidone and Olanzapine in Adult Subjects With Moderate to Severe Negative Symptoms of Schizophrenia [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacodynamics, and pharmacokinetics of co-administering roluperidone with olanzapine in ad…
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CLINICAL_TRIALS trial_result · 2025-03-26Clinical Trial Update: Culturally Adapted Cognitive Behavior Therapy Based Guided Self-help Manual for Schizophrenia Spectrum Disorder [NA]
A completed clinical trial evaluating a culturally adapted cognitive behavioral therapy guided self-help manual for schizophrenia spectrum d…
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CLINICAL_TRIALS trial_result · 2025-03-21Clinical Trial Update: Target Engagement and Response to Oxytocin [Phase 4]
A Phase 4 trial update evaluating oxytocin for schizophrenia, focusing on target engagement and clinical response. The study status is compl…