Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-03-26Clinical Trial Update: PET/MR in Assessing Response to Neoadjuvant Radiation Therapy in the Tx of High Grade Sarcomas [NA]
Clinical trial update on PET/MR for assessing response to neoadjuvant radiation therapy in high-grade sarcomas; study completed with results…
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Open Label Extension Study of Conatumumab and Ganitumab (AMG 479) [Phase 2]
Open-label extension study of Conatumumab and Ganitumab (AMG 479) in a Phase 2 trial for advanced solid tumors; completed with results poste…
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CLINICAL_TRIALS trial_result · 2021-02-03Clinical Trial Update: A Study of R1507 in Participants With Recurrent or Refractory Sarcoma [Phase 2]
Phase 2 trial of R1507 in recurrent or refractory sarcoma was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: Phase I Dose Escalation of Monthly Intravenous Ra-223 Dichloride in Osteosarcoma [Phase 1, Phase 2]
Phase I dose-escalation trial of monthly intravenous Ra-223 dichloride in sarcoma (osteosarcoma) completed with results posted.
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EMA withdrawal · 2021-01-11EMA Withdrawn: Panretin (alitretinoin) — Eisai GmbH
The EMA has withdrawn Panretin (alitretinoin) from the European market, with Eisai GmbH as the marketing authorization holder, for indicatio…
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CLINICAL_TRIALS research · 2020-12-21Clinical Trial Update: Variability of Definitions for Survival Endpoints and Surrogate Properties for OS in Sarcoma Trials: a Meta-analysis
Meta-analysis evaluating how survival endpoints and surrogate properties for overall survival vary across sarcoma trials.
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CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Gemcitabine Plus Ascorbate for Sarcoma in Adults [Phase 2]
Phase 2 clinical trial evaluating gemcitabine plus ascorbate in adults with sarcoma; trial status terminated with results posted.
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CLINICAL_TRIALS trial_result · 2020-08-27Clinical Trial Update: Stereotactic Radiation Therapy for Pediatric Sarcomas [NA]
Completed clinical trial on stereotactic radiation therapy for pediatric sarcomas with results posted.
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CLINICAL_TRIALS trial_result · 2020-06-16Clinical Trial Update: Combination Immunotherapy Targeting Sarcomas [Phase 1, Phase 2]
A clinical trial update for a combination immunotherapy targeting sarcomas across Phase 1 and Phase 2 stages, with conditions including sarc…
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CLINICAL_TRIALS trial_result · 2020-06-11Clinical Trial Update: Safety and Efficacy Evaluation of 4th Generation Safety-engineered CAR T Cells Targeting Sarcomas [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating fourth-generation safety-engineered CAR T cells for sarcomas, including osteoid sarcoma and Ewing sarc…
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CLINICAL_TRIALS trial_result · 2020-05-14Clinical Trial Update: Study to Compare the Safety and Efficacy of CMB305 With Atezolizumab to Atezolizumab Alone in Participants With Sarcoma (IMDZ-C232/V943A-002) [Phase 2]
Phase 2 trial evaluating CMB305 with atezolizumab versus atezolizumab alone in various sarcomas has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2020-04-16Clinical Trial Update: A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702) [Phase 3]
Phase 3 trial in synovial sarcoma was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-02-28Clinical Trial Update: Dose-Escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma [Phase 1, Phase 2]
Phase 1/2 dose-escalation and expansion trial of NC-6300 in advanced solid tumors and soft tissue sarcoma.
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CLINICAL_TRIALS trial_result · 2020-02-21Clinical Trial Update: Dendritic Cell-based Immunotherapy for Advanced Solid Tumours of Children and Young Adults [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating dendritic cell–based immunotherapy for advanced solid tumors in children and young adults has completed …
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Experimental Therapeutic Cancer Vaccine Created In-situ in Patients With Stage II-Stage IV Cancer [Phase 1, Phase 2]
Phase 1/2 trial update for an experimental in-situ cancer vaccine across multiple solid tumors, including breast, colorectal, prostate, mela…
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Co-treatment With GnRH Analogs on the Ovarian Reserve in Young Women Treated With Alkylating Agents for Cancer [Phase 2, Phase 3]
A Phase 2/Phase 3 trial evaluating co-treatment with GnRH analogs to protect ovarian reserve in young women receiving alkylating chemotherap…
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CLINICAL_TRIALS trial_result · 2019-12-13Clinical Trial Update: Whole-Body Hyperthermia Plus Chemotherapy in Treating Patients With Advanced Sarcoma [Phase 2]
Phase 2 clinical trial update evaluating whole-body hyperthermia plus chemotherapy in patients with advanced sarcoma has been completed.
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CLINICAL_TRIALS trial_result · 2019-11-20Clinical Trial Update: Autologous Dendritic Cell Vaccine in Patients With Soft Tissue Sarcoma [Phase 1, Phase 2]
Phase 1/2 clinical trial update evaluating an autologous dendritic cell vaccine in patients with soft tissue sarcoma.
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CLINICAL_TRIALS trial_result · 2019-10-29Clinical Trial Update: Cyclophosphamide, Topotecan, and Bevacizumab (CTB) in Patients With Relapsed/Refractory Ewing's Sarcoma and Neuroblastoma [Phase 2]
Phase 2 clinical trial evaluating a combination of cyclophosphamide, topotecan, and bevacizumab (CTB) in relapsed/refractory neuroblastoma a…
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CLINICAL_TRIALS trial_result · 2019-10-15Clinical Trial Update: Study of SHR-1210 Combined With Apatinib in the Treatment of Sarcoma [Phase 2]
Phase 2 clinical trial update investigating SHR-1210 in combination with apatinib for sarcoma.
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CLINICAL_TRIALS trial_result · 2019-10-01Clinical Trial Update: Pilot Study of Hyperthermic Peritoneal Perfusion (HIPEC) for Adolescent and Young Adults With Desmoplastic Small Round Cell Tumor [Phase 2]
Phase 2 pilot trial evaluating hyperthermic intraperitoneal perfusion (HIPEC) for adolescents and young adults with desmoplastic small round…
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CLINICAL_TRIALS trial_result · 2019-09-12Clinical Trial Update: Mix Vaccine for Metastatic Sarcoma Patients [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial update evaluating a mixed vaccine for metastatic sarcoma; study completed.
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EMA withdrawal · 2019-09-02EMA Revoked: Lartruvo (olaratumab) — Eli Lilly Nederland B.V.
The EMA revoked the marketing authorization for Larotruvo (olaratumab) by Eli Lilly Nederland B.V., effectively withdrawing approval for its…
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CLINICAL_TRIALS trial_result · 2019-05-02Clinical Trial Update: SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors) [Phase 1, Phase 2]
Clinical trial update for SARC023 evaluating ganetespib and sirolimus in malignant peripheral nerve sheath tumors (MPNST) across Phase 1 and…
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CLINICAL_TRIALS trial_result · 2019-04-01Clinical Trial Update: Treatment of Patients With RAD001 With Progressive Sarcoma [Phase 2]
Phase 2 trial evaluating RAD001 (everolimus) in patients with progressive sarcoma has completed; results posted in 2019.