Rheumatoid Arthritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-06-19Clinical Trial Update: A Clinical Evaluation of Metal Ion Release From Metal-on-Metal Cementless Total Hip Arthroplasty [NA]
This completed clinical trial evaluated metal ion release from metal-on-metal cementless total hip arthroplasty. Sponsored by Zimmer Biomet,…
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CLINICAL_TRIALS trial_result · 2017-06-19Clinical Trial Update: Phase 2, Multicenter, Open-Label Extension Study With ABT-122 in Rheumatoid Arthritis Subjects Who Have Completed the Preceding M12-963 Study [Phase 2]
This clinical trial update reports the completion and results posting of a Phase 2 open-label extension study of ABT-122 in rheumatoid arthr…
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CLINICAL_TRIALS research · 2017-06-19Clinical Trial Update: Relationship of YWHAH Polymorphisms to Rheumatoid Arthritis Disease Severity
Clinical trial investigating the relationship between YWHAH gene polymorphisms and the severity of rheumatoid arthritis; the study has compl…
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FDA approval · 2017-06-16FDA Approved: DIFLUNISAL — Original Application (Zydus Pharmaceuticals (USA) Inc.)
FDA approved a generic diflunisal product (DIFLUNISAL) under ANDA 203547 for Zydus Pharmaceuticals USA Inc. It is indicated for relief of mi…
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: Assessment of the Effectiveness of IV and SC Abatacept (Orencia) Patient Alert Cards in Patients With Rheumatoid Arthritis in a Sample of EU Countries
A completed clinical trial evaluated the effectiveness of abatacept patient alert cards (IV and SC) in patients with rheumatoid arthritis ac…
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Gene Expression Profiling in PBMCs as a Tool for Prediction of Anakinra Responsiveness in Rheumatoid Arthritis
This completed study investigates whether gene expression profiling in peripheral blood mononuclear cells can predict response to anakinra i…
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: A Study in Moderate to Severe Rheumatoid Arthritis Participants [Phase 3]
A Phase 3 clinical trial in moderate to severe rheumatoid arthritis completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: A Long-term Safety Extension Study of Tocilizumab in Brazilian Participants With Rheumatoid Arthritis (RA) Who Completed the Studies ML21530 and MA21488 [Phase 4]
Phase 4 long-term safety extension study of tocilizumab in Brazilian patients with rheumatoid arthritis who completed previous trials, asses…
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Safety, Pharmacodynamics and Pharmacokinetics of GSK2136525 Repeat Dose in Rheumatoid Arthritis [Phase 1]
This Phase 1 trial update reports on the safety, pharmacodynamics, and pharmacokinetics of repeat dosing of GSK2136525 in rheumatoid arthrit…
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Rheumatoid Arthritis Extension Trial For Subjects Who Have Participated In Other PF-05280586 Trials (REFLECTIONS B328-04) [NA]
Pfizer completed an extension trial of PF-05280586 for rheumatoid arthritis patients who had previously participated in other PF-05280586 tr…
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Hydroxytriptolide in Active Rheumatoid Arthritis Patients With an Inadequate Response to Methotrexate [Phase 1, Phase 2]
A clinical trial update reporting completed Phase 1/2 studies of hydroxytriptolide in active rheumatoid arthritis patients who did not respo…
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Reduction of Daily Sitting Time in Patients With Rheumatoid Arthritis [NA]
This trial evaluated reducing daily sitting time in patients with rheumatoid arthritis, and the study has been completed.
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: A Long Term Safety Study of Mavrilimumab in Adult Subjects With Rheumatoid Arthritis [Phase 2]
A long-term safety study of mavrilimumab in adults with rheumatoid arthritis (Phase 2) was terminated, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-05-31Clinical Trial Update: Multiple Dose Study of UCB4940 as add-on to Certolizumab Pegol in Subjects With Rheumatoid Arthritis [Phase 2]
Phase 2 trial update investigating UCB4940 as an add-on to certolizumab pegol in rheumatoid arthritis has completed.
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: Study Of 90mg Of GW274150 In Subjects Over 50 Years, Who Have Rheumatoid Arthritis (RA) [Phase 2]
A Phase 2 clinical trial update for GW274150 in adults over 50 with rheumatoid arthritis, noting that the study has completed (status COMPLE…
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CLINICAL_TRIALS trial_result · 2017-05-25Clinical Trial Update: A Study of Rofecoxib Versus Naproxen in the Treatment of Chinese Patient With Rheumatoid Arthritis (0966-231) [Phase 4]
Phase 4 trial comparing rofecoxib and naproxen in Chinese patients with rheumatoid arthritis has completed.
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CLINICAL_TRIALS research · 2017-05-25Clinical Trial Update: Injections of FloGraft Therapy, Autologous Stem Cells, or Platelet Rich Plasma for the Treatment of Degenerative Joint Pain
This clinical trial update discusses injections of FloGraft Therapy, autologous stem cells, or platelet-rich plasma for degenerative joint p…
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FDA approval · 2017-05-22FDA Approved: KEVZARA — Original Application (Sanofi-Aventis U.S. LLC)
This FDA entry documents the original approval of Kevzara (sarilumab) by Sanofi-Aventis U.S. LLC. It pertains to the initial regulatory auth…
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FDA approval · 2017-05-22FDA Approved: ACTEMRA — Supplemental Application (Genentech, Inc.)
FDA approved a supplemental application for ACTEMRA (tocilizumab) submitted by Genentech, Inc. The supplementary filing status is AP (approv…
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: GotNet Study, The Gothenburg Nurse-led Tight Control Study [NA]
The GotNet study, a nurse-led tight-control trial for rheumatoid arthritis in Gothenburg, sponsored by the Vastra Gotaland Region, has compl…
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CLINICAL_TRIALS trial_result · 2017-05-16Clinical Trial Update: Tocilizumab Effect on microRNA Expression and Adipokine Levels in Rheumatoid Arthritis Patients
A clinical trial evaluating the effect of tocilizumab on microRNA expression and adipokine levels in rheumatoid arthritis patients has compl…
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Study to Assess the Immunogenicity, Safety, and Efficacy of High Capacity Process Etanercept in Rheumatoid Arthritis Subjects [Phase 3]
A Phase 3 study assessing the immunogenicity, safety, and efficacy of a high-capacity process etanercept in rheumatoid arthritis has complet…
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Abatacept Post-marketing Clinical Study in Japan [Phase 4]
Post-marketing Phase 4 study of abatacept in Japan for rheumatoid arthritis has completed.
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Phase 1 Dose Escalating Study to Assess Safety, Tolerability, Food Effect and PK of CHR-5154 in Healthy Male Volunteers [Phase 1]
This document announces the termination of a Phase 1 dose-escalation study of CHR-5154 in healthy male volunteers, assessing safety, tolerab…
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CLINICAL_TRIALS withdrawal · 2017-05-10Clinical Trial Update: Description of Joint Population and Assessment of Impact on Health Status of Orencia in Patients With Rheumatoid Arthritis in France. A Database Analysis Based on SFR's ORA Long-term Cohort Study
The document notes the withdrawal of the NCT01694693 study evaluating abatacept (Orencia) in rheumatoid arthritis patients in France. It des…