Rheumatoid Arthritis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2017-06-21Clinical Trial Update: Total Knee Replacement Using Simplex® or Cobalt™ Bone Cement
A clinical trial comparing Simplex and Cobalt bone cements for total knee replacement has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2017-05-10Clinical Trial Update: Description of Joint Population and Assessment of Impact on Health Status of Orencia in Patients With Rheumatoid Arthritis in France. A Database Analysis Based on SFR's ORA Long-term Cohort Study
The document notes the withdrawal of the NCT01694693 study evaluating abatacept (Orencia) in rheumatoid arthritis patients in France. It des…
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CLINICAL_TRIALS withdrawal · 2017-04-13Clinical Trial Update: The Durability of Early RA Disease Control After Tocilizumab Withdrawal: A Canadian Experience
This clinical trial update discusses the durability of disease control after stopping tocilizumab in patients with early rheumatoid arthriti…
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CLINICAL_TRIALS withdrawal · 2017-03-06Clinical Trial Update: Study of Anti-Viral Prophylaxis for HBsAg(+) or HBcAb(+)/HBsAb(-) Patients Starting Anti-TNFα [Phase 3]
A Phase 3 trial evaluating antiviral prophylaxis for HBsAg-positive or HBcAb-positive/HBsAb-negative patients starting anti-TNF therapy has …
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CLINICAL_TRIALS withdrawal · 2017-01-09Clinical Trial Update: Abatacept for Patients With Inflammatory Arthritis Associated With Sjögren's Syndrome: an Open-Label Phase II Study [Phase 2]
An open-label Phase II trial evaluating abatacept for inflammatory arthritis in patients with primary or secondary Sjögren's syndrome has be…
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CLINICAL_TRIALS withdrawal · 2016-12-01Clinical Trial Update: A Dose Range Finding Study of JNJ-39758979 in Patients With Active Rheumatoid Arthritis Currently Treated With Methotrexate [Phase 2]
A Phase 2 dose-ranging trial of JNJ-39758979 in patients with active rheumatoid arthritis on methotrexate has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-11-02Clinical Trial Update: A Study of The Effect of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate on Articular Damage in The Hand in Patients With Moderate to Severe Rheumatoid Arthritis Who Have an Inadequate Response to Non-Biological DMARDs [Phase 4]
A Phase 4 trial evaluating the combination of tocilizumab (RoActemra/Actemra) with methotrexate for articular damage in the hand in rheumato…
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CLINICAL_TRIALS withdrawal · 2016-11-02Clinical Trial Update: A Non-Interventional Study in Patients With Rheumatoid Arthritis Who Are Treated With RoActemra/Actemra (Tocilizumab)
A non-interventional study of rheumatoid arthritis patients treated with RoActemra/Actemra (tocilizumab) has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-10-31Clinical Trial Update: 99m-Technetium- Glucosamine in Arthritis
A clinical trial evaluating 99m-Technetium-Glucosamine for rheumatoid arthritis and ankylosing spondylitis is no longer available, indicatin…
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CLINICAL_TRIALS withdrawal · 2016-09-20Clinical Trial Update: Open-Label Extension Safety Study of PROCRIT in Patients With Anemia of Chronic Disease Due to Rheumatoid Arthritis [Phase 2]
Open-label extension safety study of PROCRIT (epoetin alfa) in anemia of chronic disease due to rheumatoid arthritis has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-08-26Clinical Trial Update: Effects of Lacosamide on Post-operative Opioid Requirements After a Total Hip Arthroplasty: [Phase 2]
A Phase 2 trial evaluating lacosamide to reduce post-operative opioid requirements after total hip arthroplasty has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-05-11Clinical Trial Update: Effect on Orencia (Abatacept) on the Apoptosis of T Cells, B Cells and APC Cells in Rheumatoid Arthritis [Phase 4]
Phase 4 trial evaluating abatacept (Orencia) effects on apoptosis of T cells, B cells, and antigen-presenting cells in rheumatoid arthritis;…
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EMA withdrawal · 2016-04-21EMA Withdrawn: Repso (leflunomide) — Teva B.V.
The EMA has withdrawn Repso (leflunomide) from the market, a disease-modifying antirheumatic drug previously used for rheumatoid arthritis a…
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CLINICAL_TRIALS withdrawal · 2016-02-19Clinical Trial Update: Real Life Evaluation of Rheumatoid Arthritis Patients in Israel Treated With HUMIRA
An AbbVie-sponsored real-life study evaluating Humira (adalimumab) in Israeli rheumatoid arthritis patients has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2016-02-05Clinical Trial Update: Concomitant Use of Apremilast for the Treatment of Active RA Despite TNF-Inhibition and Methotrexate- CATARA [Phase 2]
A Phase 2 study evaluating concomitant apremilast for active rheumatoid arthritis in patients on TNF inhibitors and methotrexate has been wi…
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CLINICAL_TRIALS withdrawal · 2015-12-02Clinical Trial Update: A Study to Assess the Safety and Effectiveness of Golimumab in Filipino Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis
The study evaluating golimumab in Filipino patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis has been with…
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CLINICAL_TRIALS withdrawal · 2015-09-01Clinical Trial Update: Pharmacokinetic Study to Compare the Blood Levels of Low vs High Metal Manufacture of Abatacept [Phase 1]
A Phase 1 pharmacokinetic study evaluating abatacept blood levels with low versus high metal content has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-08-04Clinical Trial Update: Vitamin D Deficiency Causes Immune Dysfunction and Enables or Perpetuates the Development of Rheumatoid Arthritis [Phase 2]
A Phase 2 clinical trial evaluating whether vitamin D deficiency drives immune dysfunction and promotes rheumatoid arthritis has been withdr…
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CLINICAL_TRIALS withdrawal · 2015-06-01Clinical Trial Update: Assessment of the Disease Severity and Treatment Patterns of Rheumatoid Arthritis in Eastern Europe, Middle East and North African Countries (P08167)
The clinical trial NCT01313871 evaluating rheumatoid arthritis disease severity and treatment patterns in Eastern Europe, the Middle East an…
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CLINICAL_TRIALS withdrawal · 2015-06-01Clinical Trial Update: A Study of Immune Cells in Patients With Rheumatoid Arthritis During Different Types of Anti-TNF Alpha Treatments (Study P05521)
A study of immune cell responses in rheumatoid arthritis patients during different anti-TNF alpha therapies was withdrawn.
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CLINICAL_TRIALS withdrawal · 2015-05-28Clinical Trial Update: Effects of Tranilast on Pharmacokinetics of Methotrexate (MTX) in Patients With Rheumatoid Arthritis (RA) [Phase 1]
A Phase 1 trial examining the effect of tranilast on the pharmacokinetics of methotrexate in rheumatoid arthritis patients has been withdraw…
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CLINICAL_TRIALS withdrawal · 2015-03-17Clinical Trial Update: Safety, Pharmacokinetic (PK), Pharmcodynamic (PD), and Drug-Drug Interaction of PLX3397 in Patients With Rheumatoid Arthritis Who Are Receiving Methotrexate [Phase 1]
A Phase 1 study evaluating the safety, pharmacokinetics, pharmacodynamics, and drug-drug interactions of PLX3397 in rheumatoid arthritis pat…
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CLINICAL_TRIALS withdrawal · 2015-02-13Clinical Trial Update: The Canadian Follow-up Program for the ATTRACT Study (P04868)(TERMINATED)
The Canadian follow-up program for the ATTRACT study in rheumatoid arthritis has been terminated.
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CLINICAL_TRIALS withdrawal · 2014-08-15Clinical Trial Update: A Trial Investigating the Mechanism of Action of NNC0109-0012 (Anti-IL-20 mAb) Through Synovial Biopsies in Subjects With Rheumatoid Arthritis and an Inadequate Response to Methotrexate [Phase 2]
A Phase 2 trial investigating the mechanism of action of NNC0109-0012, an anti-IL-20 monoclonal antibody, in rheumatoid arthritis patients w…
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CLINICAL_TRIALS withdrawal · 2014-04-09Clinical Trial Update: Dataglove to Measure Joint Stiffness in Patients With Arthritis
The trial evaluating the Dataglove device to measure joint stiffness in rheumatoid arthritis patients has been withdrawn. No further updates…