Rheumatoid Arthritis
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CLINICAL_TRIALS trial_result · 2015-06-10Clinical Trial Update: Special Investigation of Humira® (Adalimumab) on Long-term Treatment in Patients With Rheumatoid Arthritis
This document reports the long-term investigation of adalimumab (Humira) in patients with rheumatoid arthritis, including results posted in …
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CLINICAL_TRIALS trial_result · 2015-06-09Clinical Trial Update: A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor [Phase 3]
A Phase 3 trial of MabThera (rituximab) in rheumatoid arthritis patients who had an inadequate response to a single anti-TNF inhibitor has c…
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CLINICAL_TRIALS trial_result · 2015-06-04Clinical Trial Update: A Trial to Determine the Effects of Exercise in Inflammatory Bowel Disease and Rheumatoid Arthritis [Phase 2]
A Phase 2 clinical trial sponsored by University College Cork to determine the effects of exercise in people with inflammatory bowel disease…
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CLINICAL_TRIALS trial_result · 2015-06-02Clinical Trial Update: 12-Week No-Rofecoxib Plus Aspirin Endoscopy Study (0782-003) [Phase 2]
Phase 2 trial of No-Rofecoxib plus aspirin for arthritis patients undergoing endoscopy was terminated.
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CLINICAL_TRIALS trial_result · 2015-05-29Clinical Trial Update: Evaluation of the Role of Adalimumab on Extraarticular Manifestation - Bone Metabolism and Bone Mineral Density in Patients With Active Rheumatoid Arthritis
A completed trial assessed the impact of adalimumab on extraarticular bone health (bone metabolism and bone mineral density) in patients wit…
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CLINICAL_TRIALS trial_result · 2015-05-29Clinical Trial Update: Autoantibodies to Gastric Parietal Cells in Rheumatoid Arthritis Patients
Clinical trial evaluating the presence of autoantibodies to gastric parietal cells in rheumatoid arthritis patients with vitamin B12 deficie…
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CLINICAL_TRIALS trial_result · 2015-05-29Clinical Trial Update: Optimal Management of Rheumatoid Arthritis Patients Requiring Biologic Therapy [Phase 4]
Phase 4 clinical trial update examining optimal management of rheumatoid arthritis patients requiring biologic therapy; the trial status is …
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CLINICAL_TRIALS trial_result · 2015-05-22Clinical Trial Update: Demonstrate the Equivalence of CT-P10 to MabThera With Respect to the Pharmacokinetic Profile in Patients With Rheumatoid Arthritis [Phase 1]
Phase 1 study demonstrates pharmacokinetic equivalence between CT-P10 and MabThera (rituximab) in patients with rheumatoid arthritis.
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CLINICAL_TRIALS trial_result · 2015-05-22Clinical Trial Update: Uncontrolled Study to Evaluate Efficacy of Tocilizumab in Patients With Moderate or Severe Rheumatoid Arthritis [Phase 4]
This clinical trial update reports on an uncontrolled Phase 4 study evaluating the efficacy of tocilizumab in patients with moderate to seve…
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CLINICAL_TRIALS trial_result · 2015-05-21Clinical Trial Update: A Two-Part, 12-Week Study of Etoricoxib as a Treatment for Rheumatoid Arthritis (RA) (MK-0663-107) [Phase 3]
Phase 3, two-part, 12-week trial of etoricoxib for rheumatoid arthritis has completed and results were posted on 2015-05-21.
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CLINICAL_TRIALS trial_result · 2015-05-20Clinical Trial Update: Aminopterin Dose Finding Treatment for Methotrexate-Naïve Rheumatoid Arthritis [Phase 2]
A Phase 2 dose-finding study of aminopterin in methotrexate-naïve rheumatoid arthritis has completed. The trial was sponsored by Syntrix Bio…
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CLINICAL_TRIALS trial_result · 2015-05-20Clinical Trial Update: Preference Between Two Autoinjectors in Patients With Rheumatoid Arthritis and Plaque Psoriasis Treated With Etanercept [Phase 4]
Phase 4 trial comparing autoinjector preferences in patients with rheumatoid arthritis and plaque psoriasis treated with etanercept; results…
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CLINICAL_TRIALS trial_result · 2015-05-19Clinical Trial Update: A Magnetic Resonance Imaging Study and Arthroscopic Biopsy Substudy in Subjects With Active Rheumatoid Arthritis Receiving VX-509, an Oral JAK3 Inhibitor [Phase 2]
A Phase 2 study of VX-509 (decernotinib), a JAK3 inhibitor, in active rheumatoid arthritis, including an MRI study and arthroscopic biopsy s…
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CLINICAL_TRIALS trial_result · 2015-05-18Clinical Trial Update: Diagnostic Value of Oral Prednisolone Test for Rheumatoid Arthritis [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial assessing the diagnostic value of an oral prednisolone challenge for rheumatoid arthritis has completed. Th…
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CLINICAL_TRIALS trial_result · 2015-05-18Clinical Trial Update: Safety,PK/PD, Food Effect Study of Orally Administered HM71224 in Healthy Adult Male Volunteers [Phase 1]
Phase 1 safety, PK/PD, and food effect study of orally administered HM71224 in healthy adult male volunteers, with rheumatoid arthritis list…
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CLINICAL_TRIALS trial_result · 2015-05-15Clinical Trial Update: A Study to Assess the Effect of Tocilizumab Plus Methotrexate on Safety and Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis [Phase 3]
This entry reports the completion and posting of Phase 3 results for a trial of tocilizumab plus methotrexate in adults with moderate-to-sev…
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CLINICAL_TRIALS trial_result · 2015-05-15Clinical Trial Update: Metal on Metal Versus Metal on Highly Crossed Linked Polyethylene Sytem [Phase 4]
Phase 4 clinical trial comparing metal-on-metal hip components with highly crosslinked polyethylene components was terminated. Sponsor: Nova…
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CLINICAL_TRIALS trial_result · 2015-05-13Clinical Trial Update: A Study To Investigate The Effect Of 28 Days Of Dosing With GW856553 On Patients With Rheumatoid Arthritis [Phase 2]
A Phase 2 study evaluating the effects of 28 days of dosing with GW856553 in patients with rheumatoid arthritis; the trial sponsored by Glax…
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CLINICAL_TRIALS trial_result · 2015-05-12Clinical Trial Update: Long-Term, Open-Label Study Of CP-690,550 For Treatment Of Rheumatoid Arthritis In Japan [Phase 3]
Long-term, open-label Phase 3 study of tofacitinib (CP-690,550) for rheumatoid arthritis conducted in Japan has completed and posted results…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Effects of Rosuvastatin on Carotid Artery Plaques in Patients With Inflammatory Joint Disease [NA]
A completed clinical trial evaluated the effect of rosuvastatin on carotid artery plaques in patients with inflammatory joint diseases, incl…
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CLINICAL_TRIALS trial_result · 2015-05-05Clinical Trial Update: Single-dose Study to Describe the Pharmacodynamics (PD) and Safety of Sarilumab (REGN88/SAR153191) and Tocilizumab in Adults With Rheumatoid Arthritis (RA) [Phase 1]
Phase 1 study evaluating the pharmacodynamics and safety of single-dose sarilumab and tocilizumab in adults with rheumatoid arthritis.
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CLINICAL_TRIALS trial_result · 2015-05-05Clinical Trial Update: Addition of H.P. Acthar Gel to Treatment Regimen of Patients With Rheumatoid Arthritis [NA]
Clinical trial update noting the addition of Acthar Gel to the treatment regimen for rheumatoid arthritis. The document does not specify a t…
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CLINICAL_TRIALS trial_result · 2015-05-04Clinical Trial Update: A Study of Retreatment With MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis (RA) [Phase 3]
This Phase 3 trial evaluated retreatment with MabThera (rituximab) in combination with methotrexate for rheumatoid arthritis and has complet…
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CLINICAL_TRIALS trial_result · 2015-04-22Clinical Trial Update: Effects of Tofacitinib (CP-690,550) on Magnetic Resonance Imaging (MRI)- Assessed Joint Structure In Early Rheumatoid Arthritis (RA) [Phase 2]
Phase 2 trial evaluating the effects of tofacitinib (CP-690,550) on MRI-assessed joint structure in patients with early rheumatoid arthritis…
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CLINICAL_TRIALS trial_result · 2015-04-16Clinical Trial Update: Aiming for Remission in Rheumatoid Arthritis (RA) - the ARCTIC Trial [Phase 4]
The ARCTIC Phase 4 trial in rheumatoid arthritis has completed, with the study status listed as COMPLETED.