Respiratory Failure
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Respiratory Knowledge Portal Computer and Phone Application to Improve Quality of Mechanical Ventilation by Reducing the Number of Ventilator Associated Events, Injury Created by the Ventilator and Unsafe Setting of Alarms. [NA]
Active clinical trial evaluating a Respiratory Knowledge Portal intended to improve quality of mechanical ventilation and reduce ventilator-…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Mechanical Insufflation in the Philadelphia Amyotrophic Lateral Sclerosis Cohort (MI-PALS) Study [NA]
This document provides an update on the MI-PALS trial investigating mechanical insufflation in a Philadelphia ALS cohort; the study status i…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Red Blood Cell Transfusion to Optimize Extubation [NA]
This entry updates the status of a study evaluating red blood cell transfusion to optimize extubation in critically ill, mechanically ventil…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Effects of Oxygen Supplementation During the 6-Minute Walk Test in Chronic Respiratory Failure or Exertional Hypoxemia [NA]
A clinical trial update on oxygen supplementation during the 6-minute walk test for people with chronic respiratory failure or exertional hy…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Physiological Study of High PEEP in Noninvasive Ventilation [NA]
This clinical trial update describes a physiological study evaluating high PEEP during noninvasive ventilation for patients with respiratory…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Randomized Study of the pdSTIM™ System in Failure to Wean Mechanically Ventilated Patients [NA]
The randomized study of the pdSTIM System in patients failing to wean from mechanical ventilation has been terminated.
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Randomized Trial of Sedative Choice for Intubation [Phase 4]
Results from a Phase 4 randomized trial comparing sedative choices for endotracheal intubation in acute respiratory failure have been posted…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Musical Intervention and Physiological Stress and Inflammatory Biomarkers in Mechanically Ventilated ICU Patients [NA]
A completed clinical trial evaluated the effects of a musical intervention on physiological stress and inflammatory biomarkers in mechanical…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Effects of L-arginine and Liposomial Vitamin C on Severe Copd Patients Undergoing Pulmonary Rehabilitation. [NA]
A completed clinical trial evaluated the effects of L-arginine and liposomal vitamin C in severe COPD patients undergoing pulmonary rehabili…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Diaphragmatic Physiology Similarity Index May Titrate HFNC Flow Setting: A Prospective Observational Study [NA]
This clinical trial update describes a prospective observational study investigating whether a Diaphragmatic Physiology Similarity Index can…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients
This clinical trial update indicates a study on exhaled breath condensate analysis in mechanically ventilated patients with acute respirator…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Vela Generation II: Usability and Performance of a Non-Invasive Ventilation Mask. [NA]
A clinical trial update on the Vela Generation II non-invasive ventilation mask evaluating usability and performance in patients with respir…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Analysis on the Fatigue and Electromyographic Activation on the Mechanical Ventilation Weaning [NA]
A completed clinical trial evaluating fatigue and electromyographic activation during ventilator weaning in ICU patients with critical illne…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Comparison of Two SpO2 Targets With Two Different Oximeters - Impact on FiO2 During Nasal High Flow Oxygen Therapy [NA]
This clinical trial is evaluating two arterial oxygen saturation targets using two different oximeters to see how they affect FiO2 during na…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Impact of Dyspnea, Regional Lung Ventilation, and Diaphragmatic Function During de Novo Acute Respiratory Failure
This entry notes that a clinical trial evaluating dyspnea, regional lung ventilation, and diaphragmatic function in patients with de novo ac…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Effects of Mobilization Using a Powered Lower-limb Exoskeleton With Prolonged Mechanical Ventilation [NA]
A clinical trial is evaluating mobilization with a powered lower-limb exoskeleton in patients on prolonged mechanical ventilation to aid ven…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Ultrasound Scoring Methods to Monitor Breathing Problems in Intensive Care Patients
This clinical trial update describes a study evaluating ultrasound scoring methods to monitor breathing problems in intensive care unit pati…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Evaluation of the Clinical and Prognostic Value of Non-invasive Analysis of Mandibular Movements (MM) as a Marker of Inspiratory Effort in the Spontaneously Breathing Intensive Care Patient [NA]
Clinical trial update evaluating non-invasive analysis of mandibular movements as a marker of inspiratory effort in spontaneously breathing …
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Impact of PEEP on Respiratory Effort During Assisted Ventilation [NA]
A clinical trial sponsored by Pontificia Universidad Catolica de Chile is examining how PEEP affects respiratory effort during assisted vent…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: From Bench to Bedside: A Machine Learning Tool for the Detection of Inspiratory Leak
A university-sponsored trial describes a machine learning tool to detect inspiratory leak in patients with chronic respiratory failure, with…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: Mode Of Ventilation During Critical IllnEss Pilot Trial [NA]
A pilot trial evaluating modes of ventilation during critical illness with respiratory failure has completed and posted results.
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: The Tele-Rehab MV Cluster Stepped-Wedge Randomized Clinical Trial [NA]
Clinical trial update indicating that the Tele-Rehab MV cluster stepped-wedge randomized trial for acute respiratory failure has completed.
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Monitoring Respiratory Muscle Function in Acute Respiratory Failure Patients on Non Invasive Respiratory Support [NA]
This entry describes a clinical trial evaluating monitoring of respiratory muscle function in acute respiratory failure patients on non-inva…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Optimizing Pain Treatment in Children On Mechanical Ventilation [Phase 3]
Phase 3 clinical trial exploring optimized pain management, including analgesia and sedation, for children requiring mechanical ventilation.
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial [NA]
METEOR is an educational and organizational research trial evaluating extubation outcomes in patients with acute respiratory failure; the st…