Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Cabozantinib Dose Skipping as an Alternative to Dose Reductions [Phase 2]
A Phase 2 study update examining cabozantinib dose skipping as an alternative to dose reductions in renal cell carcinoma.
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy [Phase 1]
Phase 1 clinical trial evaluating a vaccine therapy in combination with pembrolizumab for adults with various solid tumors that have failed …
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: SABR Combined With Targeted Therapy and Anti-PD-1 for Recurrent or Metastatic Renal Cancer
A clinical trial evaluating stereotactic ablative radiotherapy (SABR) combined with targeted therapy and anti-PD-1 therapy for recurrent or …
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy [NA]
This is an update on a clinical research study (NCT04623502) investigating kidney and urothelial tumor metabolism in patients undergoing sur…
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EMA approval · 2026-01-27EMA Authorised: Mvasi (bevacizumab) — Amgen Technology (Ireland) UC
EMA authorised Mvasi (bevacizumab) from Amgen as a biosimilar to bevacizumab for multiple cancer indications including renal cell carcinoma,…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: Sapu003 in Advanced mTOR-sensitive Solid Tumors [Phase 1]
Phase 1 trial update for Sapu003 in advanced mTOR-sensitive solid tumors, currently recruiting across multiple indications including metasta…
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EMA approval · 2026-01-27EMA Authorised: Avastin (bevacizumab) — Roche Registration GmbH
The EMA authorised Avastin (bevacizumab) under Roche Registration GmbH for multiple cancer indications. The listed diseases include non-smal…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: A Phase I/II Study to Assess the Safety and Efficacy of Vaccinations With Allogeneic Dendritic Cells: Autologous Tumor-Derived Cells Subjected to Electrofusions in Patients With AJCC Stage IV Renal Cell Carcinoma [Phase 1, Phase 2]
A Phase I/II trial evaluating the safety and preliminary efficacy of vaccinations with allogeneic dendritic cells fused with autologous tumo…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: A Study of Belzutifan (MK-6482) in Combination With Palbociclib Versus Belzutifan Monotherapy in Participants With Advanced Renal Cell Carcinoma (MK-6482-024/LITESPARK-024) [Phase 1, Phase 2]
A Phase 1/2 trial compares belzutifan in combination with palbociclib versus belzutifan alone in participants with advanced renal cell carci…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Cabozantinib In Combo With NIVO + IPI In Advanced NCCRCC [Phase 2]
Phase 2 clinical trial update evaluating cabozantinib in combination with nivolumab and ipilimumab for advanced non-clear cell renal cell ca…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Real World Evidence of Tivozanib as First-line Treatment for Metastatic Clear Cell Renal Cell Carcinoma
This completed study reports real-world evidence on using tivozanib as first-line therapy for metastatic clear cell renal cell carcinoma.
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: A Study of Nivolumab Combined With Ipilimumab Versus Nivolumab Alone in Participants With Advanced Kidney Cancer [Phase 3]
A Phase 3 trial comparing nivolumab plus ipilimumab versus nivolumab alone in advanced renal cell carcinoma; the study is currently active b…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Prospective Observational Trial of Image-guided Ablative STereotactic bOdy Radiation Therapy for Primary kidNey Cancer: the STONE Trial
Prospective observational trial evaluating image-guided ablative stereotactic body radiotherapy for primary kidney cancer; recruitment is on…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: R.E.C.K vs Exparel in Robotic Nephrectomy [Phase 3]
A Phase 3 clinical trial comparing R.E.C.K to Exparel for pain management in robotic nephrectomy, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Multi-omics Analysis of Renal Cell Carcinoma Mechanisms; Drug Sensitivity Testing in Patient-Derived Cell-based Microtumors
This clinical trial update describes a study on multi-omics analysis of Renal cell carcinoma mechanisms and drug sensitivity testing in pati…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Dynamic 82-Rb Positron Emission Tomography (PET) for the Grading of KIDney Carcinoma [Phase 2]
This is a Phase 2 clinical trial evaluating dynamic 82-Rb PET imaging to grade renal cell carcinoma, with status listed as not yet recruitin…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: Neo-adjuvant SABR for IVC Tumor Thrombus in Newly Diagnosed RCC [Phase 1, Phase 2]
A Phase 1/Phase 2 trial evaluating neoadjuvant stereotactic ablative radiotherapy for renal cell carcinoma with inferior vena cava tumor thr…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Systemic Therapy Alone or With Stereotactic Body Radiotherapy for Oligometastatic Kidney Cancer (STROKER Study) [Phase 3]
Phase 3 STROKER trial assessing systemic therapy alone versus systemic therapy plus stereotactic body radiotherapy for oligometastatic renal…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma [Phase 1]
Ongoing Phase 1 study evaluating HC-7366 in combination with belzutifan (Welireg) for renal cell carcinoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax [Phase 1]
Phase I trial updates the use of Tumor Treating Fields in combination with cabozantinib or with pembrolizumab and nab-paclitaxel for various…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors [Phase 2]
ClinicalTrials.gov update for QUILT-3.055, a Phase 2 study of combination immunotherapies in patients who previously received immune checkpo…
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CLINICAL_TRIALS other · 2026-01-14Clinical Trial Update: Phase 1b/2 Trial of Ipilimumab, Nivolumab, and Ciforadenant (Adenosine A2a Receptor Antagonist) in First-line Advanced Renal Cell Carcinoma. [Phase 1, Phase 2]
The trial at MD Anderson Cancer Center is a Phase 1b/2 study of ipilimumab, nivolumab, and ciforadenant in first-line advanced renal cell ca…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Study of Nivolumab in Combination With 177Lu-girentuximab for Kidney Cancer [Phase 2]
Phase 2 trial evaluating nivolumab in combination with 177Lu-girentuximab for renal cell carcinoma is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: A Randomized Trial of Maintenance Systemic Therapy After Radiation for Oligometastatic Renal Cell Carcinoma (ASTROs) [Phase 2]
Phase 2 randomized trial assessing maintenance systemic therapy after radiation for oligometastatic renal cell carcinoma; currently recruiti…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: The Impact of Time-of-day-Dependent Administration of Nivolumab-Ipilimumab (ICI/ICI) Combination on Overall Survival in Adults With Advanced Kidney Cancer: A Pragmatic Multicenter, Randomized Controlled Trial. [Phase 3]
A Phase 3 pragmatic multicenter randomized trial investigating whether time-of-day dependent administration of nivolumab-ipilimumab improves…