Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-06-07Clinical Trial Update: Akt Inhibitor MK2206 or Everolimus in Treating Patients With Refractory Kidney Cancer [Phase 2]
Phase 2 trial evaluating MK2206 (Akt inhibitor) or everolimus in refractory kidney cancer; study terminated with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: Evaluate Safety and Tolerability in Dose Escalation of Sorafenib in Advanced Renal Cell Cancer [Phase 2]
This Phase 2 trial update reports on the safety and tolerability findings from a dose-escalation study of sorafenib in advanced renal cell c…
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FDA approval · 2017-05-31FDA Approved: VOTRIENT — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for VOTRIENT (pazopanib hydrochloride) submitted by Novartis Pharmaceuticals Corporation. The ap…
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CLINICAL_TRIALS safety_alert · 2017-05-31Clinical Trial Update: Interleukin-2-Induced Cognitive/Affective/Sleep Symptoms
A clinical trial update notes cognitive, affective, and sleep symptoms linked to high-dose interleukin-2. The conditions involved are metast…
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CLINICAL_TRIALS research · 2017-05-31Clinical Trial Update: Everolimus TDM to Predict Long Term Toxicity
A clinical trial evaluates whether therapeutic drug monitoring of everolimus can predict long-term toxicity in cancer patients.
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: BNC105P in Combination With Everolimus/Following Everolimus For Progressive Metastatic Clear Cell Renal Cell Carcinoma [Phase 1, Phase 2]
Clinical trial update for BNC105P combined with everolimus in progressive metastatic clear cell renal cell carcinoma; phases 1 and 2 complet…
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: The High-Dose Aldesleukin (IL-2) "Select" Trial for Patients With Metastatic Renal Cell Carcinoma [Phase 2]
Phase 2 study investigating high-dose aldesleukin (interleukin-2) for metastatic renal cell carcinoma has completed with results posted in 2…
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Panobinostat and Everolimus in Treating Patients With Metastatic or Unresectable Renal Cell Cancer That Does Not Respond to Treatment With Sunitinib Malate or Sorafenib Tosylate [Phase 1, Phase 2]
Phase 1/2 trial investigating panobinostat and everolimus in metastatic or unresectable renal cell cancer after failure of sunitinib or sora…
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CLINICAL_TRIALS research · 2017-05-17Clinical Trial Update: Exhaustive Genetic and Immunological Characterization of Colon, Kidney and Liver Tumors
Clinical trial update detailing exhaustive genetic and immunological characterization of colorectal, kidney, and liver tumors.
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CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: Neoadjuvant Pazopanib in Renal Cell Carcinoma [Phase 2]
Phase 2 trial evaluating neoadjuvant pazopanib for renal cell carcinoma has completed, with results posted on May 10, 2017.
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CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: Study of Everolimus and Low-dose Cyclophosphamide in Patients With Metastatic Renal Cell Cancer [Phase 1, Phase 2]
A completed Phase 1/2 study evaluating the combination of everolimus and low-dose cyclophosphamide in patients with metastatic renal cell ca…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Efficacy and Safety of Bevacizumab Plus Sorafenib for the Third-line Treatment in Metastatic Renal Cancer Patients [Phase 2]
This document reports on a Phase 2 clinical trial evaluating the combination of bevacizumab and sorafenib as third-line therapy for metastat…
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Dual Energy CT vs Standard Triple Phase CT-A Randomised Control Trial [NA]
This entry notes a completed randomized trial comparing Dual Energy CT to Standard Triple Phase CT Angiography. The study involved patients …
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CLINICAL_TRIALS research · 2017-04-26Clinical Trial Update: Retrospective Study in Patients With Metastatic Renal Cancer Treated With TKI Sequence (Tyrosine Kinase Inhibitors of VEGFR) - mTOR- Axitinib Inhibitors or Anti-VEGF Antibody -Inhibiteurs mTOR - Axitinib
A retrospective study evaluating sequential therapy in patients with metastatic renal cell carcinoma treated with VEGFR tyrosine kinase inhi…
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method [Phase 4]
A Phase 4 trial assessing how different anesthesia methods influence cardiac arrhythmias in patients undergoing renal cell carcinoma surgery…
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: Phase III Sequential Open-label Study to Evaluate the Efficacy and Safety of Sorafenib Followed by Pazopanib Versus Pazopanib Followed by Sorafenib in the Treatment of Advanced / Metastatic Renal Cell Carcinoma (SWITCH-II) [Phase 3]
This entry documents the completed Phase III SWITCH-II trial, which compared sequences of sorafenib followed by pazopanib versus pazopanib f…
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CLINICAL_TRIALS trial_result · 2017-04-20Clinical Trial Update: NEXT: Subsequent Exposure to Tyrosine Kinase Inhibition at Recurrence After Adjuvant Therapy in Renal Cell Carcinoma [Phase 2]
Phase 2 trial update for NEXT exploring subsequent exposure to tyrosine kinase inhibition at recurrence after adjuvant therapy in renal cell…
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CLINICAL_TRIALS trial_result · 2017-04-18Clinical Trial Update: Sorafenib in Treating Patients Undergoing Surgery for Stage II, Stage III, or Stage IV Kidney Cancer [EARLY_Phase 1]
This clinical trial update reports an early-phase 1 study of sorafenib in patients undergoing surgery for stage II–IV kidney cancer, and the…
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CLINICAL_TRIALS research · 2017-04-14Clinical Trial Update: Study of the Impact of VEGF Polymorphism on the Development of Renal Carcinoma in Renal Transplant Patients
This entry describes an ongoing study examining whether VEGF gene polymorphisms influence the development of renal cell carcinoma in patient…
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: PET/CT Assessment of Tumor Perfusion in Patients With Renal Cell Carcinoma [NA]
A terminated clinical trial at Indiana University studied PET/CT assessment of tumor perfusion in renal cell carcinoma; results posted in 20…
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CLINICAL_TRIALS research · 2017-04-11Clinical Trial Update: Bortezomib and Bevacizumab ("BB-mib-mab") in Patients With Advanced or Recurrent Renal Cell Cancer (RCC) [Phase 1, Phase 2]
This document describes a Phase 1/2 trial evaluating the combination of bortezomib and bevacizumab in advanced or recurrent renal cell carci…
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: Phase II Study of Sunitinib Rechallenge in Patients With Metastatic Renal Cell Carcinoma [Phase 2]
Phase II trial evaluating sunitinib rechallenge in metastatic renal cell carcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2017-04-05Clinical Trial Update: Comparison of Microwave Ablation-Assisted Enucleation and Conventional Laparoscopic Partial Nephrectomy in the Treatment of T1a Renal Cell Carcinoma [NA]
Completed clinical trial comparing microwave ablation-assisted enucleation versus conventional laparoscopic partial nephrectomy for T1a rena…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Ziv-Aflibercept in Treating Patients With Metastatic or Unresectable Kidney Cancer [Phase 2]
Phase 2 trial update reporting results for ziv-aflibercept in patients with metastatic or unresectable kidney cancer; results were posted in…
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CLINICAL_TRIALS research · 2017-03-29Clinical Trial Update: Comparison Between Partial Nephrectomy and Ablation for Renal Tumor [NA]
This clinical trial compares partial nephrectomy and ablation for renal tumors in patients with renal cell carcinoma.