Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-12-21Clinical Trial Update: A Study of Atezolizumab (an Engineered Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) as Monotherapy or in Combination With Bevacizumab (Avastin®) Compared to Sunitinib (Sutent®) in Participants With Untreated Advanced Renal Cell Carcinoma [Phase 2]
Phase 2 trial evaluating atezolizumab alone or with bevacizumab vs sunitinib in untreated advanced renal cell carcinoma; results posted in 2…
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CLINICAL_TRIALS trial_result · 2017-12-20Clinical Trial Update: Avastin and Temsirolimus Following Tyrosine Kinase Inhibitor Failure in Patients With Advanced Renal Cell Carcinoma [Phase 2]
Phase 2 trial evaluating Avastin and Temsirolimus after tyrosine kinase inhibitor failure in advanced renal cell carcinoma has completed wit…
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CLINICAL_TRIALS trial_result · 2017-12-12Clinical Trial Update: Feasibility of a Consumer Based Accelerometer in Monitoring Outpatient Physical Activity: A Study in Patients With Cancer and Amyotrophic Lateral Sclerosis
A completed study examining the feasibility of using a consumer-based accelerometer to monitor outpatient physical activity in patients with…
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CLINICAL_TRIALS trial_result · 2017-12-08Clinical Trial Update: Anti-IMP3 Autoantibody and MicroRNA Signature Blood Tests in Finding Metastasis in Patients With Localized or Metastatic Kidney Cancer
A completed clinical trial evaluated anti-IMP3 autoantibody and microRNA signature blood tests for detecting metastasis in patients with loc…
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CLINICAL_TRIALS trial_result · 2017-12-02Clinical Trial Update: Bortezomib and Cetuximab in Treating Patients With Advanced Solid Tumors [Phase 1]
A Phase 1 trial evaluating the combination of bortezomib and cetuximab in patients with advanced solid tumors across multiple cancer types; …
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Combination Chemotherapy and Total-Body Irradiation Before Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer, Metastatic Breast Cancer, or Kidney Cancer [Phase 1, Phase 2]
A Phase 1/2 trial update on using combination chemotherapy and total-body irradiation before donor umbilical cord blood transplant in patien…
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CLINICAL_TRIALS trial_result · 2017-11-28Clinical Trial Update: Study on the Influence of Sunitinib and Sorafenib on Fatigue, QoL, Depression in Patients With Metastatic RCC or GIST
A completed clinical trial evaluated the impact of sunitinib and sorafenib on fatigue, quality of life, and depression in patients with meta…
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CLINICAL_TRIALS trial_result · 2017-11-22Clinical Trial Update: Second Line Sorafenib After Pazopanib in Patients With RCC [Phase 2]
A Phase 2 trial evaluating second-line sorafenib after prior pazopanib in metastatic renal cell carcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Study Of Safety And Tolerability Of GW786034 Given With Lapatinib In Cancer Patients [Phase 1]
Phase 1 study evaluating the safety and tolerability of GW786034 in combination with lapatinib in cancer patients, including those with rena…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: A Two-way Crossover Study Of The Effect Of Food On The Pharmacokinetics Of Pazopanib In Cancer Patients [Phase 1]
A Phase 1 two-way crossover study assessed the effect of food on the pharmacokinetics of Pazopanib in cancer patients to inform dosing consi…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: Part A: Radiolabel Study With GW786034 Part B: Single Dose of GW786034 [Phase 1]
Phase 1 clinical trial update for GW786034 in renal cell carcinoma, with Part A radiolabel study and Part B single-dose evaluation. The stud…
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FDA approval · 2017-11-16FDA Approved: SUTENT — Supplemental Application (U.S. Pharmaceuticals)
FDA has approved a supplemental application for Sutent (sunitinib malate) submitted by U.S. Pharmaceuticals. This entry documents the supple…
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: VEG111485: A QTc Study of Pazopanib [Phase 1]
This update covers the completion of a Phase 1 QTc study evaluating pazopanib in renal cell carcinoma.
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Oral Topotecan As A Radiosensitizing Agent In Rectal Cancer [Phase 1]
Phase 1 trial evaluating oral topotecan as a radiosensitizing agent in rectal cancer was terminated.
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CLINICAL_TRIALS trial_result · 2017-11-14Clinical Trial Update: Open Label, Single Arm Trial to Characterize Patients With Metastatic RCC Treated With Everolimus After Failure of the First VEGF-targeted Therapy (MARC-2) [Phase 4]
Open-label, single-arm Phase 4 trial evaluating everolimus in patients with metastatic renal cell carcinoma after failure of the first VEGF-…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Caphosol in Oral Mucositis Due to Targeted Therapy [Phase 3]
A Phase 3 trial evaluating Caphosol for oral mucositis caused by targeted cancer therapies has completed.
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Phase I Study of Pazopanib Alone and In Combination With Lapatinib in Japanese Patients With Solid Tumors [Phase 1]
Phase I trial evaluating Pazopanib alone and in combination with Lapatinib in Japanese patients with solid tumors, including renal cell carc…
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: An Open-Label Pharmacodynamic Study of Bevacivumab and Pazopanib in Renal Cell Carcinoma [Phase 1]
This is a completed Phase 1, open-label pharmacodynamic study evaluating the combination of bevacizumab and pazopanib in renal cell carcinom…
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CLINICAL_TRIALS research · 2017-11-13Clinical Trial Update: A Study To Test The Effect Of GW786034 (Pazopanib) On P450 Enzymes [Phase 1]
Phase 1 study to evaluate the effect of pazopanib (GW786034) on cytochrome P450 enzymes to understand potential drug interactions; the trial…
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EMA withdrawal · 2017-11-10EMA Application withdrawn: Kyomarc (bevacizumab) — Amgen Europe B.V.
The EMA withdrew the application for Kyomarc (bevacizumab) from Amgen Europe B.V., relating to several carcinomas and neoplasms.
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CLINICAL_TRIALS trial_result · 2017-11-09Clinical Trial Update: Sorafenib in Elderly mRCC
Completed clinical trial update on sorafenib in elderly patients with metastatic renal cell carcinoma.
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CLINICAL_TRIALS trial_result · 2017-11-09Clinical Trial Update: Exploratory Study Evaluating Fluorodeoxyglucose - Position Emission Tomography as a Predictive Marker for Therapy With RAD001 in Metastatic Renal Cell Cancer [Phase 2]
Phase 2 exploratory study evaluating FDG-PET as a predictive marker for RAD001 (everolimus) therapy in metastatic renal cell carcinoma; resu…
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CLINICAL_TRIALS trial_result · 2017-11-07Clinical Trial Update: Trial Comparing Stereotactic Body Radiation Therapy to Radiofrequency Ablation for Renal Cell Carcinoma [NA]
A clinical trial comparing stereotactic body radiation therapy with radiofrequency ablation for renal cell carcinoma was terminated and resu…
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CLINICAL_TRIALS trial_result · 2017-11-01Clinical Trial Update: RGD-PET-CT in Cancer Angiogenesis [Phase 2]
Phase 2 trial of RGD-PET-CT imaging for cancer angiogenesis in renal cell carcinoma was terminated.
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CLINICAL_TRIALS research · 2017-10-16Clinical Trial Update: Dried Blood SPOT Analysis of Everolimus in Cancer Patients (SPOT-study)
Completed clinical study evaluating dried blood spot sampling to measure everolimus exposure in cancer patients (SPOT-study), led by Radboud…