Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-07-26Clinical Trial Update: Observational Study Evaluating The Efficacy And Effects On Quality Of Life Of Targeted Treatments Following TKIs In mRCC
Observational study assessing efficacy and quality of life effects of targeted treatments after TKIs in renal cell carcinoma.
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CLINICAL_TRIALS trial_result · 2019-07-26Clinical Trial Update: Phase I Biomarker Study (BMS-936558) [Phase 1]
Phase I biomarker study of BMS-936558 in renal cell carcinoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-07-24Clinical Trial Update: Low-Dose Total-Body Irradiation and Fludarabine Phosphate Followed By Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Stage IV Kidney Cancer [Phase 1, Phase 2]
Phase 1/2 trial investigating low-dose total-body irradiation and fludarabine phosphate followed by donor peripheral blood stem cell transpl…
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FDA approval · 2019-06-27FDA Approved: ZIRABEV — Original Application (Pfizer Laboratories Div Pfizer Inc)
FDA approves ZIRABEV (bevacizumab-bvzr) from Pfizer as a biosimilar to Avastin under an Original Application. The approval covers multiple b…
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CLINICAL_TRIALS trial_result · 2019-06-24Clinical Trial Update: A Trial of Everolimis in Patients With Advanced Renal Cell Carcinoma. [Phase 4]
Phase 4 clinical trial update for everolimus in advanced renal cell carcinoma, with completed status and results posted.
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CLINICAL_TRIALS trial_result · 2019-06-21Clinical Trial Update: A Study Of Avelumab In Combination With Axitinib In Advanced Renal Cell Cancer (JAVELIN Renal 100) [Phase 1]
Phase 1 trial evaluating avelumab plus axitinib in advanced renal cell cancer has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-06-21Clinical Trial Update: A Dose Finding Study To Evaluate Safety, Drug Interaction, Tumor Markers Of Axitinib In Combination With MK-3475 In Adult Patients With Previously Untreated Advanced Renal Cell Cancer [Phase 1]
Phase 1 trial updating safety, drug interaction, and tumor marker data for axitinib in combination with MK-3475 in adults with previously un…
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CLINICAL_TRIALS trial_result · 2019-06-10Clinical Trial Update: Pilot Study of Pazopanib With Low Fat Meal (PALM) in Advanced Renal Cell Carcinoma [EARLY_Phase 1]
Early phase 1 pilot study evaluating pazopanib with a low-fat meal in advanced renal cell carcinoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-06-03Clinical Trial Update: Effects of Anesthesia on Immunity in Cancer [Phase 4]
Phase 4 trial evaluating how anesthesia affects immunity in cancer patients undergoing surgery for renal cancer has completed.
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FDA approval · 2019-05-17FDA Approved: PROLEUKIN — Supplemental Application (Iovance Biotherapeutics, Inc)
FDA approved a supplemental application for PROLEUKIN (aldesleukin) filed by Iovance Biotherapeutics. The approval updates the product label…
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CLINICAL_TRIALS trial_result · 2019-04-30Clinical Trial Update: Two and Three Dimensional Contrast-enhanced Ultrasound for Screening of Renal Cell Carcinoma Recurrence Following Cryoablation [Phase 2]
Phase 2 trial evaluating two- and three-dimensional contrast-enhanced ultrasound for screening renal cell carcinoma recurrence after cryoabl…
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CLINICAL_TRIALS trial_result · 2019-04-29Clinical Trial Update: Clinical Outcome Of Advanced Renal Cell Carcinoma In Taiwan
A completed clinical trial update reporting outcomes for advanced renal cell carcinoma in Taiwan; results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-03-06Clinical Trial Update: Everolimus With or Without Bevacizumab in Treating Patients With Advanced Kidney Cancer That Progressed After First-Line Therapy [Phase 3]
A Phase 3 trial evaluating everolimus with or without bevacizumab in advanced kidney cancer that progressed after first-line therapy was ter…
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CLINICAL_TRIALS trial_result · 2019-02-27Clinical Trial Update: A Study of E7080 Alone, and in Combination With Everolimus in Subjects With Unresectable Advanced or Metastatic Renal Cell Carcinoma Following One Prior Vascular Endothelial Growth Factor (VEGF)-Targeted Treatment [Phase 1, Phase 2]
Phase 1/2 trial of E7080 (lenvatinib) alone and with everolimus in unresectable/metastatic renal cell carcinoma after prior VEGF therapy; st…
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CLINICAL_TRIALS trial_result · 2019-02-08Clinical Trial Update: Study of Lenvatinib in Combination With Everolimus in Participants With Unresectable Advanced or Metastatic Renal Cell Carcinoma (RCC) [Phase 1]
Phase 1 study evaluating lenvatinib in combination with everolimus in unresectable advanced or metastatic renal cell carcinoma has completed…
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CLINICAL_TRIALS research · 2019-02-08Clinical Trial Update: PET Quantitative Assessments of Solid Tumor Response to Immune Checkpoint Blockade Therapy [EARLY_Phase 1]
This Clinical Trial Update reports on an early-phase 1 study using PET quantitative assessments to measure solid tumor response to immune ch…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Sequential Therapy in Metastatic Renal Cell Carinoma [Phase 2]
The document notes completion of a Phase 2 clinical trial evaluating sequential therapy for metastatic renal cell carcinoma, sponsored by th…
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CLINICAL_TRIALS trial_result · 2019-01-18Clinical Trial Update: A Study of LY2584702 With Erlotinib or Everolimus in Participants With Solid Tumors [Phase 1]
A Phase 1 trial evaluating LY2584702 combined with erlotinib or everolimus in patients with solid tumors was terminated, and results have be…
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CLINICAL_TRIALS trial_result · 2019-01-03Clinical Trial Update: Tivantinib With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Locally Advanced Kidney Cancer That Cannot Be Removed by Surgery [Phase 2]
Phase 2 trial evaluating tivantinib with or without erlotinib in metastatic or locally advanced renal cell carcinoma that cannot be surgical…
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CLINICAL_TRIALS trial_result · 2018-12-21Clinical Trial Update: Cabozantinib-s-malate or Sunitinib Malate in Treating Patients With Previously Untreated Locally Advanced or Metastatic Kidney Cancer [Phase 2]
Phase 2 trial comparing cabozantinib-s-malate versus sunitinib in untreated locally advanced or metastatic kidney cancer completed with resu…
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CLINICAL_TRIALS trial_result · 2018-12-19Clinical Trial Update: An Investigational Immuno-Therapy Safety and Efficacy Study of Multiple Administration Regimens for Nivolumab Plus Ipilimumab in Subjects With Renal Cell Carcinoma [Phase 2]
Phase 2 trial evaluating multiple administration regimens of nivolumab plus ipilimumab in renal cell carcinoma has completed with results po…
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CLINICAL_TRIALS trial_result · 2018-12-06Clinical Trial Update: Sunitinib Malate Related Fatigue in Patients With Metastatic Kidney Cancer [NA]
Clinical trial update on sunitinib-related fatigue in metastatic/advanced renal cell cancer was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2018-11-28Clinical Trial Update: Treatment of Patients With Advanced Renal Cancer With a Radiolabeled Antibody, Yttrium-90 Conjugated Chimeric G250 [Phase 1]
Phase 1 trial evaluating a radiolabeled antibody with Yttrium-90 for advanced renal cancer has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2018-11-20Clinical Trial Update: Sorafenib Combined With Chemotherapy for Renal Collecting Duct Carcinoma [Phase 2]
Phase 2 study evaluating sorafenib in combination with chemotherapy for renal cell carcinoma has completed.
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CLINICAL_TRIALS withdrawal · 2018-11-15Clinical Trial Update: A Study of Atezolizumab in Combination With Bevacizumab in Untreated Locally Advanced or Metastatic Clear Cell or Non-Clear Cell Renal Cell Carcinoma [Phase 3]
A Phase 3 trial evaluating atezolizumab with bevacizumab in untreated locally advanced or metastatic renal cell carcinoma has been withdrawn…