Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Akt Inhibitor MK2206 and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors, Melanoma, Prostate or Kidney Cancer [Phase 1]
Phase 1 trial update on MK-2206 plus hydroxychloroquine for advanced solid tumors, including melanoma, prostate cancer, and renal cell carci…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma [Phase 1]
Phase 1 clinical trial update on QXL138AM assessing safety, pharmacokinetics, and preliminary efficacy in patients with solid tumors and mul…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors [Phase 1]
Phase 1 trial evaluating cabozantinib S-malate with nivolumab, with or without ipilimumab, in patients with metastatic genitourinary tumors;…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy [Phase 1, Phase 2]
Clinical trial evaluating oral 7HP349 (Alintegimod) in combination with ipilimumab, followed by nivolumab monotherapy, in patients with adva…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing Cabozantinib With or Without Atezolizumab in Patients With Advanced Papillary Kidney Cancer, PAPMET2 Trial [Phase 2]
Phase 2 PAPMET2 trial evaluates cabozantinib with or without atezolizumab in patients with advanced papillary renal cell carcinoma, includin…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Neoadjuvant Pembrolizumab and Axitinib in Renal Cell Carcinoma With Inferior Vena Cava Tumor Thrombus [Phase 2]
A Phase 2 neoadjuvant trial of pembrolizumab plus axitinib for renal cell carcinoma with inferior vena cava tumor thrombus is currently recr…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Phase 2 Study of Belzutifan (PT2977, MK-6482) for the Treatment of Von Hippel Lindau (VHL) Disease-Associated Renal Cell Carcinoma (RCC) (MK-6482-004) [Phase 2]
Phase 2 clinical trial update for belzutifan (PT2977, MK-6482) in Von Hippel-Lindau disease-associated renal cell carcinoma; the study (NCT0…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Study of Minimally-invasive Ablative Renal Therapies (SMART) Registry
The SMART Registry, a study of minimally-invasive ablative renal therapies for renal cell carcinoma, is currently suspended. Sponsor is the …
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EMA approval · 2026-04-09EMA Authorised: Sorafenib Accord (sorafenib tosilate) — Accord Healthcare S.L.U.
The EMA authorised Sorafenib Accord (sorafenib tosylate) for hepatocellular carcinoma and renal cell carcinoma. Accord Healthcare S.L.U. is …
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain Metastases [Phase 2]
This clinical trial update outlines a Phase II study of nivolumab with ipilimumab and cabozantinib in patients with untreated renal cell car…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Safety, PK and Efficacy of AI-061 in Advanced Solid Tumors [Phase 1]
Phase 1 update reporting safety, pharmacokinetics, and preliminary efficacy data for AI-061 in advanced solid tumors across multiple indicat…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: A Phase 1 Study of the Safety and Tolerability of CTX-10726 [Phase 1]
Phase 1 study update on the safety and tolerability of CTX-10726, currently recruiting across gastroesophageal cancer, hepatocellular carcin…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Kidney Cancer DNA Registry
An ongoing kidney cancer DNA registry study sponsored by Memorial Sloan Kettering Cancer Center is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study of Abemaciclib and Cabozantinib in People With Clear Cell Renal Cell Carcinoma (ccRCC) [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating the combination of abemaciclib and cabozantinib in metastatic renal cell c…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: A Study of Participant Reported Preference for Subcutaneous Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) Over Intravenous Pembrolizumab (MK-3475) Formulation in Multiple Tumor Types (MK-3475A-F11) [Phase 2]
Phase 2 study compares subcutaneous pembrolizumab coformulated with hyaluronidase alfa (MK-3475A) to intravenous pembrolizumab in multiple t…
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CLINICAL_TRIALS safety_alert · 2026-04-08Clinical Trial Update: Vascular Toxicities of Immune ChecKpoint Inhibitors : From Bed to Benchside [NA]
A clinical trial update outlining vascular toxicities observed with immune checkpoint inhibitors, highlighting safety signals and implicatio…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial [Phase 2]
Phase 2 SAMURAI trial is evaluating the addition of stereotactic radiation therapy with immunotherapy for unresectable or metastatic renal c…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors [Phase 1]
This clinical trial update reports a Phase 1 dose-determining study of EXS74539 (REC-4539) in participants with select solid tumors, current…
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CLINICAL_TRIALS trial_result · 2026-04-08Clinical Trial Update: CBCT Guided Markerless SBRT for Renal Cell Cancer [NA]
A clinical trial evaluating CBCT-guided markerless SBRT for renal cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of AK104 Plus Axitinib in Advanced/Metastatic Special Pathological Subtypes of Renal Cell Carcinoma [Phase 1, Phase 2]
A clinical trial update on AK104 plus axitinib in advanced/metastatic special pathological subtypes of renal cell carcinoma (Phase 1/Phase 2…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of VET3-TGI in Patients With Solid Tumors [Phase 1]
Phase 1 clinical trial update for VET3-TGI in patients with solid tumors, currently recruiting across multiple cancer types.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer [Phase 3]
Phase 3 trial evaluating adding tivozanib to pembrolizumab after surgery for kidney cancer; currently recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC) [Phase 1]
A first-in-human Phase 1 trial evaluating BMS-986506 in adults with advanced clear cell renal cell carcinoma (ccRCC); recruitment is ongoing…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers [Phase 1, Phase 2]
This clinical trial update describes a CD70-targeted CAR-T cell therapy using patients' peripheral blood lymphocytes to treat CD70-expressin…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy [NA]
A clinical trial update comparing single-dose versus multiple-dose radiation in cancer patients with brain metastases who are receiving immu…