Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Rhomboid Intercostal and Subserratus Plane Block Versus Quadratus Lumborum Block in Management of Postoperative Pain After Open Nephrectomy [NA]
This clinical trial compares rhomboid intercostal and subserratus plane block versus quadratus lumborum block for postoperative pain control…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Study of Cabozantinib in Combination With Nivolumab and Ipilimumab in Patients With Previously Untreated Advanced or Metastatic Renal Cell Carcinoma [Phase 3]
Phase 3 study evaluating cabozantinib in combination with nivolumab and ipilimumab for previously untreated advanced or metastatic renal cel…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: A Study Evaluating AB248 Alone or in Combination With Pembrolizumab in Adult Patients With Solid Tumors [Phase 1]
Phase 1 trial update evaluating AB248 alone or with pembrolizumab in adults with solid tumors, including non-small cell lung cancer, melanom…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Deep Learning for Automated Discrimination Between Stage T1-T2 and T3 Renal Cell Carcinoma on Contrast-Enhanced CT
This study is currently recruiting to evaluate a deep learning method that automatically discriminates between early-stage (T1-T2) and stage…
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CLINICAL_TRIALS other · 2025-09-10Clinical Trial Update: A Comparison of Vorolanib Tablets Combined With Everolimus Versus Sunitinib in Patients With Advanced Renal Cell Carcinoma Who Have Progressed After Treatment With Immunotherapy Monotherapy or in Combination With TKI [Phase 3]
A Phase 3 trial protocol compares Vorolanib tablets plus Everolimus against Sunitinib in advanced renal cell carcinoma patients who progress…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial [Phase 3]
The PROBE trial is a Phase 3 study evaluating immunotherapy-based combination therapy for metastatic renal cell carcinoma with or without su…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression [Phase 1, Phase 2]
A2 Biotherapeutics is evaluating A2B395, an allogeneic logic-gated CAR T therapy, in Phase 1/2 trials for solid tumors expressing EGFR and l…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Inulin Gel in Combination With Ipilimumab and Nivolumab for the Treatment of Metastatic or Locally Advanced Kidney Cell Cancer, ICON Trial [Phase 1, Phase 2]
Clinical trial update describing the ICON study, evaluating a combination of an inulin gel with ipilimumab and nivolumab for locally advance…
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: Exploring Relevant Immune-based Biomarkers and Circulating Tumor Cells During Treatment With Immunotherapy in Genitourinary Malignancies (CTC Immune Based Biomarkers)
This clinical trial update describes a Duke University study evaluating immune-based biomarkers and circulating tumor cells in patients trea…
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CLINICAL_TRIALS trial_result · 2025-09-08Clinical Trial Update: Fecal Microbiota Transplantation to Improve Efficacy of Immune Checkpoint Inhibitors in Renal Cell Carcinoma [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluating fecal microbiota transplantation to enhance the efficacy of immune checkpoint inhibitors in …
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Envafolimab Combined With Axitinib as First-Line Treatment for Patients With Advanced Renal Cell Carcinoma [Phase 2]
A Phase 2 clinical trial is evaluating Envafolimab in combination with Axitinib as first-line therapy for advanced renal cell carcinoma; the…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Evaluating the Bacterial and Fungal Microbiome in Patients With Calcium Oxalate Urolithiasis and Renal Cell Carcinoma
A University of Miami-led clinical trial evaluating the bacterial and fungal microbiome in patients with calcium oxalate urolithiasis and re…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Application of the "Off-Clamp And Sutureless" Technique in Robot-Assisted Partial Nephrectomy [NA]
Clinical trial update on applying an off-clamp and sutureless technique in robot-assisted partial nephrectomy for renal cell carcinoma, with…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: NSAID Use After Robotic Partial Nephrectomy [Phase 2]
This is a Phase 2 clinical trial sponsored by the University of Miami evaluating NSAID use after robotic partial nephrectomy for kidney/rena…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Clinical Trial to Assess the Importance of Nephrectomy [Phase 3]
A Phase 3 trial update evaluating the role of nephrectomy in metastatic renal cell carcinoma has been completed.
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Stereotactic Radiotherapy for Renal Cancers [NA]
A completed clinical trial evaluating stereotactic radiotherapy for renal cancers, sponsored by Hospices Civils de Lyon, has finished.
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FDA approval · 2025-09-04FDA Approved: PAZOPANIB — Original Application (Torrent Pharmaceuticals Limited)
FDA approves Torrent Pharmaceuticals Limited's pazopanib hydrochloride as an original generic application (ANDA 219922).
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: The Pharmacological Effects of Using Cabozantinib With a Light Breakfast [Phase 2]
Phase 2 pharmacology study evaluating the effects of taking cabozantinib with a light breakfast in patients with renal cell carcinoma; compl…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: A Study of Multimodal Radiotherapy for Renal Cell Carcinoma Progressed After Prior Immunotherapy [Phase 2]
A Phase 2 clinical trial from Jinling Hospital in China is investigating multimodal radiotherapy for renal cell carcinoma that progressed af…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: A Study of Adjuvant Intismeran Autogene (V940) and Pembrolizumab in Renal Cell Carcinoma (V940-004). [Phase 2]
Phase 2 clinical trial update of Adjuvant Intismeran Autogene (V940) with pembrolizumab in renal cell carcinoma; the study is currently acti…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Ivonescimab in the Treatment of Multiple Advanced Tumors [Phase 2]
An update indicating Ivonescimab is being studied in a Phase 2 trial for multiple advanced tumors and is currently recruiting. The trial cov…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Study of ST-1898 in Advanced Renal Cell Carcinoma [Phase 1, Phase 2]
Clinical trial update for ST-1898 in advanced renal cell carcinoma, currently in Phase 1/Phase 2 and not recruiting.
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Study to Compare Tivozanib in Combination With Nivolumab to Tivozanib Monotherapy in Subjects With Renal Cell Carcinoma [Phase 3]
Phase 3 trial comparing tivozanib plus nivolumab to tivozanib alone in renal cell carcinoma; the study is active but not recruiting.
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Neoadjuvant Lenvatinib and Pembrolizumab for IVC Tumor Thrombus [Phase 2]
Phase 2 clinical trial updating recruitment for neoadjuvant therapy with lenvatinib and pembrolizumab in renal cell carcinoma with inferior …
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CLINICAL_TRIALS withdrawal · 2025-08-19Clinical Trial Update: PSMA Therapy and Immunotherapy in Kidney Cancer [Phase 1, Phase 2]
A clinical trial investigating PSMA-targeted therapy and immunotherapy for metastatic renal cell carcinoma has been withdrawn.