Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors [Phase 2]
This Phase 2 clinical trial update reports recruitment for an alternative cabozantinib dosing schedule in metastatic renal cell carcinoma an…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Immediate Versus Deferred Cytoreductive Nephrectomy With Ipilimumab/Nivolumab in mRCC [NA]
A clinical trial compares immediate versus deferred cytoreductive nephrectomy in metastatic renal cell carcinoma using ipilimumab and nivolu…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: The HistoSonics Investigational System for Treatment of Primary Solid Renal Tumors Using Histotripsy [NA]
The clinical trial evaluating the HistoSonics Investigational System for histotripsy treatment of primary solid renal tumors has completed w…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Decision Aid (DA) for Renal Patients [NA]
This document reports an ongoing clinical trial about a decision-aid tool for patients with kidney cancer/renal tumors, which is currently r…
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: An Observational Study to Evaluate the Efficacy and Safety of Avelumab + Axitinib Combination in Participants With aRCC (AVION)
An observational study evaluating the efficacy and safety of the Avelumab + Axitinib combination in participants with advanced renal cell ca…
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Toripalimab in Combination With Axitinib Versus Sunitinib Monotherapy in Advanced Renal Cell Cancer [Phase 3]
This Phase 3 trial compares toripalimab plus axitinib against sunitinib monotherapy in unresectable or metastatic renal cell carcinoma; the …
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: Comparing Two Different Approaches in Robotic-Assisted Renal Surgery [NA]
A completed clinical trial comparing two robotic-assisted approaches for renal tumor surgery.
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Naptumomab Estafenatox in Combination With Durvalumab in Subjects With Selected Advanced or Metastatic Solid Tumor, Including a Cohort Expansion in Esophageal Cancer. [Phase 1]
Phase 1 trial update of Naptumomab Estafenatox in combination with durvalumab in selected advanced or metastatic solid tumors, including eso…
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: Study of ACC-1898 in Adult Participants With Advanced Solid Tumors [Phase 1]
Phase 1 study update for ACC-1898 in adults with advanced solid tumors; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: International Multicentric Study ARON-1
ARON-1 is an international multicenter clinical trial sponsored by the Hospital of Macerata. It targets metastatic renal cell carcinoma and …
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: Pembrolizumab and Lenvatinib in Patients With Brain Metastases From Melanoma or Renal Cell Carcinoma [Phase 2]
Phase 2 trial of pembrolizumab plus lenvatinib for brain metastases from melanoma or renal cell carcinoma has been terminated; the update no…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers [Phase 2, Phase 3]
The DETERMINE trial treatment arm 01 is evaluating Alectinib in adult, paediatric and teenage/young adult patients with ALK-positive cancers…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Study to Evaluate LB-LR1109, Administered Alone for the Treatment of Solid Tumor and in Combination With Atezolizumab for the Treatment of NSCLC [Phase 1]
Phase 1 trial evaluating LB-LR1109 alone and in combination with atezolizumab for solid tumors, including non-small cell lung cancer, curren…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Neutrophil Biomarker Test for Predicting Clinical Benefit From Immunotherapy Based on Flow Cytometry Analysis
This clinical trial update describes a flow cytometry-based neutrophil biomarker test intended to predict clinical benefit from immunotherap…
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EMA approval · 2025-11-21EMA Authorised: Yervoy (Ipilimumab) — Bristol-Myers Squibb Pharma EEIG
The European Medicines Agency authorised Yervoy (ipilimumab) for multiple cancer indications. It lists melanoma, renal cell carcinoma, non-s…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors [Phase 1]
This is a Phase 1 clinical trial update for HiFiBiO's HFB200301 as a single agent and in combination with tislelizumab in adults with advanc…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: A Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of HFB200603 as a single agent and in combination with tislelizumab in adults with advanced solid tumors, including renal cell…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed?
A recruiting clinical trial in women with isolated acute cystitis and macroscopic hematuria to evaluate the need for further investigation o…
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: Clinical Trial Addressing the Best Surgical Approach for Partial Nephrectomy With Single Port Robotic System in the Management of Localized Renal Cell Carcinoma [NA]
This trial is evaluating the best surgical approach for partial nephrectomy using a single-port robotic system to treat localized renal cell…
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EMA approval · 2025-11-20EMA Authorised: Afinitor (everolimus) — Novartis Europharm Limited
EMA authorised Afinitor (everolimus) for renal cell carcinoma, breast cancer and pancreatic neoplasms. The marketing authorisation holder is…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Evaluation of Hemostatic Agents in Partial Nephrectomy [NA]
A completed clinical trial evaluating hemostatic agents used during partial nephrectomy to assess bleeding control in localized renal cell c…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: FMT in Checkpoint Inhibitor-mediated Diarrhea and Colitis [NA]
Clinical trial update on fecal microbiota transplantation to treat checkpoint inhibitor–induced diarrhea and colitis; currently RECRUITING a…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Study of BL-B01D1+TKI±Pembrolizumab in Patients With Locally Advanced or Metastatic Renal Cancer [Phase 2]
This is a Phase 2 clinical trial evaluating BL-B01D1 with a tyrosine kinase inhibitor, with or without pembrolizumab, in patients with local…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: A Study of Cabozantinib and Nivolumab With Radiation Therapy for People With Renal Cell Carcinoma That Has Spread to the Brain [Phase 1]
Phase 1 study evaluating the combination of cabozantinib and nivolumab with radiation therapy for metastatic renal cell carcinoma with brain…
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CLINICAL_TRIALS research · 2025-11-13Clinical Trial Update: Stereotactic Magnetic Resonance Guided Radiation Therapy [NA]
Clinical trial update on stereotactic MR-guided radiation therapy for multiple cancer types; recruitment is ongoing.