Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study [Phase 3]
PDIGREE is a Phase 3 trial evaluating nivolumab plus ipilimumab followed by nivolumab with or without cabozantinib in advanced renal cell ca…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study [Phase 2]
Phase 2 trial exploring the addition of radium-223 dichloride to cabozantinib for advanced renal cell carcinoma with bone metastases (RadiCa…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: GCAR1, a Chimeric Antigen Receptor (CAR) T-CELL Therapy for Relapsed/Refractory GPNMB-Expressing Solid Tumours [Phase 1]
Phase 1 trial of GCAR1 CAR T-cell therapy for GPNMB-expressing solid tumors; study targets alveolar soft-part sarcoma, renal cell carcinoma,…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Akt Inhibitor MK2206 and Hydroxychloroquine in Treating Patients With Advanced Solid Tumors, Melanoma, Prostate or Kidney Cancer [Phase 1]
Phase 1 trial update on MK-2206 plus hydroxychloroquine for advanced solid tumors, including melanoma, prostate cancer, and renal cell carci…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma [Phase 1]
Phase 1 clinical trial update on QXL138AM assessing safety, pharmacokinetics, and preliminary efficacy in patients with solid tumors and mul…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors [Phase 1]
Phase 1 trial evaluating cabozantinib S-malate with nivolumab, with or without ipilimumab, in patients with metastatic genitourinary tumors;…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy [Phase 1, Phase 2]
Clinical trial evaluating oral 7HP349 (Alintegimod) in combination with ipilimumab, followed by nivolumab monotherapy, in patients with adva…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Testing Cabozantinib With or Without Atezolizumab in Patients With Advanced Papillary Kidney Cancer, PAPMET2 Trial [Phase 2]
Phase 2 PAPMET2 trial evaluates cabozantinib with or without atezolizumab in patients with advanced papillary renal cell carcinoma, includin…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Neoadjuvant Pembrolizumab and Axitinib in Renal Cell Carcinoma With Inferior Vena Cava Tumor Thrombus [Phase 2]
A Phase 2 neoadjuvant trial of pembrolizumab plus axitinib for renal cell carcinoma with inferior vena cava tumor thrombus is currently recr…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain Metastases [Phase 2]
This clinical trial update outlines a Phase II study of nivolumab with ipilimumab and cabozantinib in patients with untreated renal cell car…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Kidney Cancer DNA Registry
An ongoing kidney cancer DNA registry study sponsored by Memorial Sloan Kettering Cancer Center is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Study of Abemaciclib and Cabozantinib in People With Clear Cell Renal Cell Carcinoma (ccRCC) [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating the combination of abemaciclib and cabozantinib in metastatic renal cell c…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial [Phase 2]
Phase 2 SAMURAI trial is evaluating the addition of stereotactic radiation therapy with immunotherapy for unresectable or metastatic renal c…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Dose Determining Study of EXS74539 (REC-4539) in Participants With Select Solid Tumors [Phase 1]
This clinical trial update reports a Phase 1 dose-determining study of EXS74539 (REC-4539) in participants with select solid tumors, current…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of AK104 Plus Axitinib in Advanced/Metastatic Special Pathological Subtypes of Renal Cell Carcinoma [Phase 1, Phase 2]
A clinical trial update on AK104 plus axitinib in advanced/metastatic special pathological subtypes of renal cell carcinoma (Phase 1/Phase 2…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study of VET3-TGI in Patients With Solid Tumors [Phase 1]
Phase 1 clinical trial update for VET3-TGI in patients with solid tumors, currently recruiting across multiple cancer types.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer [Phase 3]
Phase 3 trial evaluating adding tivozanib to pembrolizumab after surgery for kidney cancer; currently recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A First-in-Human Study of BMS-986506 in Participants With Advanced Clear Cell Renal Cell Carcinoma (ccRCC) [Phase 1]
A first-in-human Phase 1 trial evaluating BMS-986506 in adults with advanced clear cell renal cell carcinoma (ccRCC); recruitment is ongoing…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy [NA]
A clinical trial update comparing single-dose versus multiple-dose radiation in cancer patients with brain metastases who are receiving immu…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain [Phase 3]
Phase 3 trial comparing longer-duration radiation therapy versus standard radiation therapy for patients with cancer that has spread to the …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Neoadjuvant Zanzalintinib Plus Nivolumab in Patients With Locally Advanced and/or Inoperable Clear Cell Renal Cell Carcinoma With or Without Non-measurable Metastasis [Phase 2]
A Phase 2 neoadjuvant trial evaluating Zanzalintinib plus nivolumab for locally advanced or inoperable clear cell renal cell carcinoma (with…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Cancer and Blood Pressure Management, CARISMA Study [NA]
An ECOG-ACRIN clinical trial update on the CARISMA study, investigating cancer care with blood pressure management in patients with cardiova…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Focused Radiation Versus Systemic Therapy for Kidney Cancer Patients With Limited Metastasis, SOAR Study [Phase 3]
A Phase 3 trial (SOAR) is evaluating focused radiation versus systemic therapy for kidney cancer with limited metastasis; the study is curre…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Stereotactic Body Proton Therapy for Treatment of Primary Renal Cell Carcinoma [Phase 2]
Phase 2 clinical trial evaluating stereotactic body proton therapy for primary renal cell carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC [Phase 2]
This is a Phase 2 clinical trial update for Zanzalintinib (XL092) in combination with immunotherapy for advanced or metastatic renal cell ca…