Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2016-10-31Clinical Trial Update: Sentinel Lymph Node Mapping in Rectal Cancer [NA]
This clinical trial update concerns sentinel lymph node mapping in rectal cancer, with the current trial status listed as unknown.
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CLINICAL_TRIALS research · 2016-10-25Clinical Trial Update: The Feasibility and Safety of Instruments in Transanal Total Mesorectal Excision (TaTME) for Rectal Cancer [Phase 1, Phase 2]
Clinical Trial Update reporting on the feasibility and safety of instruments used in transanal total mesorectal excision (TaTME) for rectal …
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CLINICAL_TRIALS research · 2016-10-24Clinical Trial Update: A Prospective Phase II Randomized Clinical Trial of Preoperative Chemotherapy Combined With Short-course Radiotherapy Versus Conventional Neo-adjuvant Therapy for Locally Advanced Rectal Cancer Implemented by MDT [Phase 2]
Phase II randomized trial comparing preoperative chemotherapy with short-course radiotherapy versus conventional neoadjuvant therapy for loc…
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CLINICAL_TRIALS trial_result · 2016-10-19Clinical Trial Update: Safety and Efficacy Study to Compare Capecitabine + Bevacizumab Versus Capecitabine, Concomitantly With Radiotherapy as Neoadjuvant Treatment for Patients With Localized and Resectable Rectal Cancer [Phase 2]
This Phase 2 trial compares capecitabine plus bevacizumab with radiotherapy to capecitabine with radiotherapy as neoadjuvant treatment for l…
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CLINICAL_TRIALS trial_result · 2016-10-19Clinical Trial Update: Optimal Surgery and MRI Based Radiochemotherapy in Rectal Carcinoma
This completed study evaluated the combination of optimized surgery and MRI-based radiochemotherapy for rectal cancer at stages II and III.
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CLINICAL_TRIALS trial_result · 2016-10-17Clinical Trial Update: The Effects of a 9 Week Exercise Programme on Fitness and Quality of Life in Rectal Cancer Patients After Chemoradiotherapy and Before Surgery [NA]
This clinical trial evaluates the impact of a 9-week exercise program on fitness and quality of life in rectal cancer patients after chemora…
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: Chemotherapy and Radiation Therapy Before Surgery Followed by Capecitabine With or Without Oxaliplatin in Treating Patients With Locally Advanced Rectal Cancer [Phase 3]
Phase 3 trial evaluating neoadjuvant chemoradiation with capecitabine, with or without oxaliplatin, followed by surgery in locally advanced …
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CLINICAL_TRIALS withdrawal · 2016-10-12Clinical Trial Update: Regorafenib in Reducing Recurrence in Patients With Non-metastatic Rectal Cancer Who Have Completed Curative-Intent Treatment [Phase 2]
The document notes that the Phase 2 trial of regorafenib to reduce recurrence in non-metastatic rectal cancer after curative treatment has b…
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CLINICAL_TRIALS trial_result · 2016-10-11Clinical Trial Update: Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study [Phase 3]
A Phase 3 randomized, blinded crossover trial comparing loperamide to placebo for ileostomy output in patients with rectal cancer, ulcerativ…
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CLINICAL_TRIALS trial_result · 2016-10-07Clinical Trial Update: Influence of Somatuline Autogel 120mg on Post-operative Drainage After Total Mesorectum Excision for Rectumcarcinoma [Phase 3]
A Phase 3 trial evaluating whether Somatuline Autogel 120 mg affects postoperative drainage after total mesorectal excision for rectal cance…
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CLINICAL_TRIALS trial_result · 2016-09-29Clinical Trial Update: Oxaliplatin and 5-FU Based Preoperative Chemoradiation [Phase 2]
Phase 2 trial evaluating oxaliplatin and 5-fluorouracil-based preoperative chemoradiation for rectal cancer; the study status is completed.
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CLINICAL_TRIALS trial_result · 2016-09-22Clinical Trial Update: Mesorectal Excision (ME) Versus ME With Lateral Node Dissection for Stage II, III Lower Rectal Cancer (JCOG0212) [Phase 3]
A phase 3 trial comparing mesorectal excision alone versus mesorectal excision with lateral node dissection in stage II–III lower rectal can…
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CLINICAL_TRIALS trial_result · 2016-09-21Clinical Trial Update: Oxaliplatin, Leucovorin, and Fluorouracil Before and After Radiation Therapy and Surgery in Treating Patients With Rectal Cancer That Can Be Removed by Surgery [Phase 2]
Phase 2 study evaluating FOLFOX (oxaliplatin, leucovorin, and fluorouracil) given before and after radiation therapy and surgery for patient…
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CLINICAL_TRIALS trial_result · 2016-09-19Clinical Trial Update: Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal Cancer [Phase 2, Phase 3]
This is a clinical trial update for a Phase 2/Phase 3 study evaluating transanual tube placement in low anterior resection for rectal cancer…
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CLINICAL_TRIALS trial_result · 2016-09-12Clinical Trial Update: Pre-operative 5-Fluorouracil (5-FU) and Sorafenib With External Radiation in Locally Advanced Rectal Cancer [Phase 1]
A Phase 1 trial assessing pre-operative combination therapy with 5-fluorouracil and sorafenib with external beam radiation for locally advan…
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CLINICAL_TRIALS trial_result · 2016-09-09Clinical Trial Update: The Predictive Value of Cytokines on Response to Preoperative Chemoradiotherapy in Patients With Rectal Cancer
A completed trial evaluated whether cytokine biomarker levels can predict response to preoperative chemoradiotherapy in rectal cancer.
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CLINICAL_TRIALS trial_result · 2016-09-07Clinical Trial Update: A Trial of Neoadjuvant FOLFOX6 With Short Course Radiotherapy in Patients With Unresectable Rectal Cancer and Liver Metastasis [Phase 2]
A Phase 2 trial evaluating neoadjuvant FOLFOX6 with short-course radiotherapy for unresectable rectal cancer with liver metastasis has compl…
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CLINICAL_TRIALS trial_result · 2016-09-02Clinical Trial Update: Radiation Therapy, Surgery, and Chemotherapy in Treating Patients With Rectal Cancer That Can Be Surgically Removed [Phase 3]
Phase 3 clinical trial update on using radiation therapy, surgery, and chemotherapy for patients with resectable rectal cancer.
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CLINICAL_TRIALS trial_result · 2016-08-30Clinical Trial Update: Multicentric Study an Endoscopic Treatment of Digestive Neoplasia by Submucosal Dissection Evaluation of a New Water Jet System [NA]
A multicenter study evaluating a new water jet system for endoscopic submucosal dissection to treat digestive neoplasia has completed.
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CLINICAL_TRIALS trial_result · 2016-08-30Clinical Trial Update: LifeSeal™ Pilot Study in Subjects Undergoing Circular Stapled Anastomosis Created Within 10 cm of the Anal Verge [NA]
A completed pilot clinical trial evaluating the LifeSeal device in subjects undergoing circular stapled anastomosis within 10 cm of the anal…
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CLINICAL_TRIALS trial_result · 2016-08-25Clinical Trial Update: A Study of Xeloda (Capecitabine) Plus Radiotherapy in Participants With Locally Advanced Rectal Cancer [Phase 2]
Phase 2 trial evaluating Xeloda (capecitabine) with radiotherapy in locally advanced rectal cancer; the study completed with results posted …
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CLINICAL_TRIALS trial_result · 2016-08-01Clinical Trial Update: Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy With 5-Fluorouracil and Oxaliplatin Versus 5-Fluorouracil Alone in Rectal Cancer [Phase 3]
Phase 3 trial evaluating neoadjuvant chemoradiotherapy and adjuvant chemotherapy with 5-fluorouracil and oxaliplatin versus 5-fluorouracil a…
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CLINICAL_TRIALS trial_result · 2016-08-01Clinical Trial Update: Community Dissemination of an Evidence-based Colorectal Cancer (CRC) Screening Intervention [NA]
This update reports the completion of a clinical trial evaluating the community dissemination of an evidence-based colorectal cancer screeni…
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CLINICAL_TRIALS trial_result · 2016-07-22Clinical Trial Update: Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR Inhibitors
This clinical trial update reports termination of studies evaluating EGFR inhibitors across multiple cancers, including anal, colon/rectal c…
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CLINICAL_TRIALS withdrawal · 2016-07-15Clinical Trial Update: Feasibility Study to Develop Sentinel Lymph Node Mapping in Rectal Cancer Patients [NA]
A feasibility study on sentinel lymph node mapping in rectal cancer patients has been withdrawn.