Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Gender Differences in Robotic Surgery for Rectal Cancer: a Retrospective Study
A completed retrospective study evaluating gender differences in outcomes after robotic surgery for rectal cancer.
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE -01 Study [Phase 2]
Phase 2 RELIEVE-01 trial from Fudan University is evaluating organ preservation with tislelizumab plus total neoadjuvant therapy in patients…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: The Effects of Temporary Ileostomy on Outcome in Patients With Rectal Cancer [NA]
A completed clinical trial examining how a temporary ileostomy affects outcomes in patients with rectal cancer.
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CLINICAL_TRIALS withdrawal · 2024-04-29Clinical Trial Update: Regorafenib and XmAb20717 in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy (RX-CROME) [Phase 2]
A Phase 2 trial RX-CROME evaluating regorafenib with XmAb20717 for high-risk colorectal cancer patients with radiographic occult molecular r…
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CLINICAL_TRIALS research · 2024-04-29Clinical Trial Update: Study of Fruquintinib Combined With Tegafur Gimeracil Oteracil in Patients With Metastatic Colorectal Cancer [Phase 2]
A Phase 2 clinical trial is evaluating the combination of Fruquintinib with S-1 (tegafur/gimeracil/oteracil) in patients with metastatic col…
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Neoadjuvant Chemoradiotherapy With Sequential Ipilimumab and Nivolumab in Rectal Cancer [Phase 2]
Phase 2 trial update evaluating neoadjuvant chemoradiotherapy followed by sequential ipilimumab and nivolumab in rectal cancer has completed…
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CLINICAL_TRIALS trial_result · 2024-03-26Clinical Trial Update: A Study of Total Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 clinical trial investigating total neoadjuvant therapy for high-risk locally advanced rectal cancer; current status is unknown.
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CLINICAL_TRIALS trial_result · 2024-03-12Clinical Trial Update: 64Cu-ATSM PET/CT in Rectum Cancer (TEP 64Cu-ATSM-Rectum) [Phase 2]
Phase 2 clinical trial update evaluating 64Cu-ATSM PET/CT in rectal cancer.
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CLINICAL_TRIALS trial_result · 2024-03-07Clinical Trial Update: Neoadjuvant Bevacizumab + Chemotherapy Combined With Short-course Radiotherapy [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating neoadjuvant bevacizumab plus chemotherapy with short-course radiotherapy for rectal cancer; current st…
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CLINICAL_TRIALS trial_result · 2024-02-07Clinical Trial Update: Combination of AK104 and Neoadjuvant Chemoradiotherapy in pMMR/MSS Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 clinical trial update evaluating the combination of AK104 with neoadjuvant chemoradiotherapy in locally advanced rectal cancer wit…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: PROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing Surgery [Phase 2, Phase 3]
A randomized trial comparing chemotherapy alone versus chemotherapy plus radiation therapy in locally advanced rectal cancer undergoing surg…
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CLINICAL_TRIALS trial_result · 2024-02-02Clinical Trial Update: Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer [Phase 2]
A single-arm Phase II exploratory study evaluating envafolimab with chemoradiotherapy for locally advanced pMMR/MSS rectal cancer; current s…
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: Short-course Radiation Followed by mFOLFOX-6 Plus COMPOUND 2055269 for Locally-advanced Rectal Adenocarcinoma [Phase 2]
Phase 2 clinical trial update evaluating short-course radiation followed by mFOLFOX-6 plus COMPOUND 2055269 for locally advanced rectal aden…
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CLINICAL_TRIALS trial_result · 2024-01-29Clinical Trial Update: Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi) [Phase 3]
Phase 3 trial evaluating total neoadjuvant treatment with or without immunotherapy for high-risk locally advanced rectal cancer is currently…
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CLINICAL_TRIALS trial_result · 2024-01-23Clinical Trial Update: Genetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial
The COLOMATE trial evaluating genetic testing in screening patients with metastatic or unresectable colon or rectal cancer has terminated, w…
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: Investigate the Efficacy of Chemotherapy in Patients With Positive ctDNA After Surgery and Adjuvant Chemotherapy for a Stage III Colorectal Cancer [Phase 3]
Phase 3 clinical trial evaluating chemotherapy efficacy in colorectal cancer patients with positive ctDNA after surgery and adjuvant chemoth…
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: Mechanical Bowel Preparation and Oral Antibiotics Before Rectal Cancer Surgery [Phase 3]
Phase 3 clinical trial update evaluating mechanical bowel preparation and oral antibiotics before rectal cancer surgery has completed.
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CLINICAL_TRIALS trial_result · 2023-12-04Clinical Trial Update: Induction Chemotherapy Before or After Preoperative Chemoradiotherapy and Surgery for Locally Advanced Rectal Cancer [Phase 2]
Phase 2 trial comparing induction chemotherapy before or after preoperative chemoradiotherapy and surgery for locally advanced rectal cancer…
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: Short Course Radiation Therapy Followed by Pre-operative Chemotherapy and Surgery in High-risk Rectal Cancer [Phase 2]
Phase 2 clinical trial update evaluating short-course radiation therapy followed by pre-operative chemotherapy and surgery for high-risk rec…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: Combination Immunotherapy in Subjects With Advanced HPV Associated Malignancies [Phase 1, Phase 2]
This clinical trial update reports Phase 1/2 results for a combination immunotherapy regimen in adults with advanced HPV-associated cancers.…
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer [Phase 3]
Phase 3 trial comparing neoadjuvant chemoradiotherapy to total neoadjuvant therapy for T3 rectal cancer; not yet recruiting.
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: TNT to Increase the Clinical Complete Response Rate for Distal LARC [Phase 2]
Phase 2 clinical trial update aiming to increase clinical complete response rate for distal locally advanced rectal cancer (LARC) undergoing…
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CLINICAL_TRIALS trial_result · 2023-10-19Clinical Trial Update: Immunotherapy In Locally Advanced Rectal Cancer [Phase 2]
Phase 2 clinical trial update on immunotherapy for locally advanced rectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2023-10-11Clinical Trial Update: Neoadjuvant Chemotherapy With PD-1 Inhibitors Combined With SIB-IMRT in the Treatment of Locally Advanced Rectal Cancer [Phase 3]
Phase 3 trial evaluating neoadjuvant chemotherapy with PD-1 inhibitors plus SIB-IMRT for locally advanced rectal cancer is currently recruit…
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CLINICAL_TRIALS trial_result · 2023-10-05Clinical Trial Update: Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer [Phase 1]
Phase 1 trial evaluating the addition of IPdR, a radiation-sensitizing drug, to standard capecitabine-based chemoradiation for locally advan…