Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Peritoneum and Anterior Rectus Sheath Suturing and Ileostomy [NA]
Clinical trial update for a surgical technique involving peritoneum and anterior rectus sheath suturing with ileostomy in rectal cancer. The…
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CLINICAL_TRIALS research · 2024-10-16Clinical Trial Update: Exosomes in Rectal Cancer
A University of Kansas Medical Center-sponsored clinical trial is evaluating exosome-based approaches for rectal cancer. The study is curren…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Virtual Ileostomy Versus Diverting Ileostomy
The trial comparing virtual ileostomy and diverting ileostomy for rectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-10-10Clinical Trial Update: NEO: Neoadjuvant Chemotherapy, Excision and Observation for Early Rectal Cancer [Phase 2]
Phase 2 trial evaluating neoadjuvant chemotherapy, surgical excision, and observation for early rectal cancer. The study is completed with r…
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: Evaluating the Impact of Financial Navigation on Financial Catastrophe and Distress for Cancer Care [NA]
A clinical trial evaluating whether financial navigation reduces financial distress and financial catastrophe for cancer patients, currently…
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial [NA]
This clinical trial update notes a randomized controlled trial evaluating neoadjuvant chemoradiotherapy with consolidation chemotherapy for …
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: The Combination of Hypofractionated Radiotherapy and Immunotherapy in Locally Recurrent Rectal Cancer [Phase 2]
Phase 2 trial evaluating hypofractionated radiotherapy combined with immunotherapy for locally recurrent rectal cancer is currently recruiti…
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CLINICAL_TRIALS research · 2024-09-27Clinical Trial Update: Study of the Predictive and Prognostic Role of Pharmacogenetic and Radiogenic Variants on the Response to Neoadjuvant Chemoradiation Therapy in Patients With Locally Advanced Rectal Cancer
This clinical trial protocol investigates how pharmacogenetic and radiogenic variants may predict or prognosticate response to neoadjuvant c…
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CLINICAL_TRIALS research · 2024-09-26Clinical Trial Update: Multi-Technology Integrated Total Mesorectal Excision Versus Conventional Total Mesorectal Excision for the Treatment of Middle and Distal Rectal Cancer. [NA]
A clinical trial comparing multi-technology integrated total mesorectal excision to conventional total mesorectal excision for middle and di…
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CLINICAL_TRIALS research · 2024-09-20Clinical Trial Update: Radical vs Local Excision for Rectal Cancer With Clinically Complete Remission [NA]
This update describes an ongoing clinical trial comparing radical versus local excision for rectal cancer patients with clinically complete …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Short RT Versus RCT,Followed by Chemo.and Organ Preservation for Interm and High-risk Rectal Cancer Patients [Phase 3]
A Phase 3 trial compares short radiotherapy versus chemoradiation followed by chemotherapy with organ preservation in intermediate- and high…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: ctDNA Monitoring to Predict the Efficacy of TNT for Rectal Cancer
A clinical trial update indicates recruitment for a study using ctDNA monitoring to predict the efficacy of Total Neoadjuvant Therapy in rec…
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Tucatinib Combined with Trastuzumab and TAS-102 for the Treatment of HER2 Positive Metastatic Colorectal Cancer in Molecularly Selected Patients, 3T Study [Phase 2]
A Phase 2 trial evaluating tucatinib in combination with trastuzumab and TAS-102 for HER2-positive metastatic colorectal cancer in molecular…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Trial Comparing Loop Ileostomy Versus Loop Transverse Colostomy [NA]
A clinical trial comparing loop ileostomy and loop transverse colostomy in rectal neoplasms has completed.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Neoadjuvant Moderately Hypofractionated Radiotherapy Combined with Chemotherapy and Immunotherapy for High-risk LARC [Phase 2]
Phase 2 clinical trial exploring neoadjuvant moderately hypofractionated radiotherapy combined with chemotherapy and immunotherapy for high-…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Exploring the Effect of Colonic J-pouch in Anorectal Preservation Surgery for Ultra-low Rectal Cancer.
This clinical trial update describes an ongoing study evaluating Colonic J-pouch reconstruction to preserve anorectal function after ultra-l…
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CLINICAL_TRIALS research · 2024-08-23Clinical Trial Update: Conformal Sphincter-Preservation Operation Versus InterSphincteric Resection on Anal Function in Low Rectal Cancer [NA]
This clinical trial update describes a not-yet-recruiting study comparing two sphincter-preserving surgical approaches for low rectal cancer…
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CLINICAL_TRIALS trial_result · 2024-08-22Clinical Trial Update: Short-course Radiotherapy Followed by Tislelizumab + CapeOX in the Treatment for Locally Advanced Rectal Cancer [Phase 2]
Phase 2 trial evaluating short-course radiotherapy followed by tislelizumab combined with CapeOX for locally advanced rectal cancer has comp…
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Chemoradiotherapy After Surgery Versus Preoperative Chemoradiotherapy for Stage II/III Mid-low Rectal Cancer With or Without High-risk Factors
A clinical trial comparing chemoradiotherapy after surgery versus before surgery for stage II/III mid-low rectal cancer; the trial status is…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: COLOR II: Laparoscopic Versus Open Rectal Cancer Removal [Phase 3]
COLOR II is a Phase 3 trial comparing laparoscopic versus open rectal cancer surgery; this update notes the trial has completed.
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: Liver Magnetic Resonance Imaging Before Treatment for Rectal Cancer. A Randomised Controlled Trial. [NA]
An ongoing randomized controlled trial is evaluating liver MRI before treatment in patients with rectal cancer.
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: The Effect of Minimally Invasive Surgery on Systemic Inflammatory Response in Rectal Cancer
A clinical trial evaluating the effect of minimally invasive surgery on the systemic inflammatory response in rectal/colorectal cancer, curr…
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer [Phase 1]
A Phase 1 study evaluating the combination of PolyPEPI1018 vaccine and TAS-102 in metastatic colorectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: Optimisation of Response for Organ Preservation in Rectal Cancer : Neoadjuvant Chemotherapy and Radiochemotherapy vs. Radiochemotherapy [Phase 3]
This clinical trial update notes the completion of a Phase 3 study comparing neoadjuvant chemotherapy plus radiochemotherapy to radiochemoth…
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CLINICAL_TRIALS research · 2024-08-14Clinical Trial Update: Chemotherapy Followed by Pelvic Reirradiation Versus Chemotherapy Alone as Pre-operative Treatment for Locally Recurrent Rectal Cancer [Phase 3]
Phase 3 clinical trial comparing chemotherapy followed by pelvic reirradiation versus chemotherapy alone as pre-operative treatment for loca…