Rectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: CLASSICA: Validating AI in Classifying Cancer in Real-Time Surgery
A clinical trial update for CLASSICA, evaluating AI to classify cancer in real-time during rectal surgery, currently recruiting.
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: Transanal Versus Laparoscopic Total Mesorectal Excision for Rectal Cancer [NA]
This document reports an ongoing clinical trial comparing transanal with laparoscopic total mesorectal excision for rectal cancer, with pati…
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: The Combination of Immunotherapy and Neoadjuvant Short-course Radiotherapy in Early Rectal Cancer [Phase 2]
This is a Phase 2 clinical trial update describing the investigation of combining immunotherapy with neoadjuvant short-course radiotherapy f…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Nodes-sparing Short-course Radiation Combined With CAPOX and Tislelizumab for MSS Middle and Low Rectal Cancer [Phase 2]
A Phase 2 trial is evaluating nodes-sparing short-course radiation combined with CAPOX chemotherapy and tislelizumab for microsatellite-stab…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer. [Phase 2, Phase 3]
Phase 2/3 clinical trial comparing total neoadjuvant therapy with organ preservation versus surgery for rectal cancer; recruitment is ongoin…
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Adebrelimab Injection (PD-L1) Combined With Short Course Radiotherapy and Chemotherapy for Neoadjuvant Therapy of Locally Advanced Rectal Cancer [Phase 2]
Phase 2 trial of Adebrelimab (PD-L1) with short-course radiotherapy and chemotherapy as neoadjuvant treatment for locally advanced rectal ca…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Short-course Radiotherapy Followed by CAPOX and Ivonescimab for Locally Advanced Rectal Cancer [Phase 2]
Phase 2 clinical trial examining short-course radiotherapy followed by CAPOX chemotherapy and Ivonescimab for locally advanced rectal cancer…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Total Neoadjuvant Treatment Without Surgery For Locally Advanced Rectal Cancer [Phase 2]
Phase 2 clinical trial update reporting results of total neoadjuvant therapy without surgery for locally advanced rectal cancer.
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Preoperative Chemoradiotherapy and Toripalimab in Locally Recurrent Rectal Cancer [Phase 2]
A Phase 2 trial to evaluate preoperative chemoradiotherapy combined with toripalimab for locally recurrent rectal cancer; the study is curre…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Consolidation Chemotherapy for Locally Advanced Mid or Low Rectal Cancer After Neoadjuvant Concurrent Chemoradiotherapy [Phase 3]
Phase 3 clinical trial evaluating consolidation chemotherapy after neoadjuvant chemoradiotherapy for locally advanced mid- or low-rectal can…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer
This entry updates a clinical trial evaluating how long PD-1 neoadjuvant therapy should be given for stage II-III mismatch repair-deficient …
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: Circulating Tumor DNA-guided Neoadjuvant Treatment Strategy for Locally Advanced Rectal Cancer [Phase 2]
A Phase 2 trial evaluating a circulating tumor DNA-guided neoadjuvant treatment strategy for locally advanced rectal cancer is currently rec…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: A Prospective Study of Expression Profiling-based Assessment of the Efficacy of Neoadjuvant Therapy for Rectal Cancer
This clinical trial update describes a prospective study using expression profiling to assess the efficacy of neoadjuvant therapy for rectal…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: External Beam Radiotherapy Combined with Endorectal High-dose-rate Brachytherapy in Elderly and Frail Patients with Rectal Cancer [NA]
This clinical trial investigates external beam radiotherapy combined with endorectal high-dose-rate brachytherapy for rectal cancer in elder…
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: CB-839 + Capecitabine in Solid Tumors and Fluoropyrimidine Resistant PIK3CA Mutant Colorectal Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating CB-839 (telaglenastat) with capecitabine in fluoropyrimidine-resistant colorectal cancer and other solid tumors h…
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: Short-Course Radiotherapy Followed by Neoadjuvant Chemotherapy, HLX07and Serplulimab in LARC [Phase 2]
A Phase 2 trial evaluating short-course radiotherapy followed by neoadjuvant chemotherapy with HLX07 and serplulimab in locally advanced rec…
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: PRediction of Outcomes and PERsonalized Radiotherapy by Biomarkers and Functional Imaging [NA]
This entry describes an ongoing clinical trial investigating biomarkers and functional imaging to predict outcomes and personalize radiother…
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Comparison of Sphincter Preservation Surgery and Abdominoperineal Resection (APR): Prospective Clinical Trial [NA]
A completed prospective clinical trial comparing sphincter-preserving surgery with abdominoperineal resection for rectal cancer.
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CLINICAL_TRIALS research · 2024-12-04Clinical Trial Update: Total Neoadjuvant Treatment of Rectal Cancer by MRI-guided Radiotherapy
This clinical trial entry notes an ongoing investigation of total neoadjuvant treatment for rectal cancer using MRI-guided radiotherapy, cur…
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CLINICAL_TRIALS research · 2024-12-03Clinical Trial Update: Neoadjuvant Radiotherapy Before Surgery for Rectal Cancer, Surgical and Oncological Outcome Analysis, Retrospective Case Control Study in a Single Institute.
A retrospective case-control study from a single institute evaluates surgical and oncological outcomes of neoadjuvant radiotherapy before su…
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: Spanish Registry of Digestive Tumours RETUD
This entry notes the RETUD Spanish registry for digestive tumours is currently recruiting, sponsored by the Spanish Cooperative Group for th…
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CLINICAL_TRIALS research · 2024-12-02Clinical Trial Update: Study of the Prevalence of Sexual Dysfunction in Women After Rectal Cancer Surgery and Analysis of the Impact of a Sexologist Intervention [NA]
This ClinicalTrials.gov study investigates how common sexual dysfunction is in women after rectal cancer surgery and evaluates the impact of…
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: Impact of a Patient-Centered Program for Low Anterior Resection Syndrome a Multicenter Randomized Controlled Trial [NA]
A multicenter randomized trial evaluating a patient-centered program for Low Anterior Resection Syndrome after rectal cancer surgery has com…
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CLINICAL_TRIALS trial_result · 2024-11-27Clinical Trial Update: M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability [Phase 1, Phase 2]
Phase 1/2 clinical trial results for bintrafusp alfa (M7824) in metastatic colorectal cancer and MSI-H advanced solid tumors have been poste…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Chemoradiation and Consolidation Chemotherapy With or Without Oxaliplatin for Distal Rectal Cancer and Watch and Wait [NA]
A clinical trial is evaluating chemoradiation with consolidation chemotherapy, with or without oxaliplatin, for distal rectal cancer and a w…