Pulmonary Tuberculosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-09-13Clinical Trial Update: Phase 2 Trial to Evaluate the Early Bactericidal Activity, Safety and Tolerability of Meropenem Plus Amoxycillin/CA and Faropenem Plus Amoxycillin/CA in Adult Patients With Newly Diagnosed Pulmonary Tuberculosis [Phase 2]
Phase 2 trial evaluating meropenem/amoxicillin-clavulanate and faropenem/amoxicillin-clavulanate for early bactericidal activity, safety, an…
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Ex-vivo Antitubercular Activity of PBTZ169 Formulation [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics and ex-vivo antitubercular activity of the PBTZ169 formulation has completed…
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CLINICAL_TRIALS research · 2018-04-24Clinical Trial Update: Rifampicin vs Rifabutin in HIV/AIDS Patients Combined With Tuberculosis [NA]
A clinical trial compares rifampicin versus rifabutin in patients with HIV/AIDS and pulmonary tuberculosis.
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Oral Urea Breath Testing for Diagnosis and Treatment Response in Pulmonary Tuberculosis
This completed trial evaluated oral urea breath testing as a diagnostic tool and method to monitor treatment response in pulmonary tuberculo…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Utility of MODS for Diagnosis of MDR-TB and Second-Line Antituberculous Drug Susceptibility Testing in Mali
The terminated trial assessed the MODS test for diagnosis of multidrug-resistant tuberculosis and for second-line antituberculous drug susce…
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Performance Evaluation of TB Breath- and Cough-testing Platforms
This clinical trial update reports on the performance evaluation of breath- and cough-based diagnostic platforms for pulmonary tuberculosis.
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CLINICAL_TRIALS withdrawal · 2017-07-02Clinical Trial Update: Pimonidazole Hydrochloride to Detect Low Oxygen in Tuberculosis-Infected Lungs [Phase 2]
A Phase 2 trial investigating pimonidazole hydrochloride to detect low oxygen in tuberculosis-infected lungs has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-06-01Clinical Trial Update: ENOSE in Pulmonary Tuberculosis in Yogyakarta [NA]
The ENOSE trial investigating pulmonary tuberculosis and related COPD conditions in Yogyakarta has completed.
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CLINICAL_TRIALS research · 2017-05-05Clinical Trial Update: IGRA and Mantoux Response in Children With Suspected Latent or Active TB Infection
Clinical trial update examining IGRA (interferon-gamma release assay) and Mantoux test responses in children with suspected latent or active…
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: Comparison Between Two Strategies for the Diagnosis of TB [NA]
A completed clinical trial comparing two diagnostic strategies for pulmonary tuberculosis. Sponsor: Hopital Lariboisière.
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (TMC207-CL001) [Phase 2]
Phase 2 study evaluating the early bactericidal activity of bedaquiline (TMC207) in pulmonary tuberculosis; results were posted after comple…
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CLINICAL_TRIALS research · 2017-04-13Clinical Trial Update: Evaluation of 11C-acetate PET Imaging as a Novel Approach to Detecting Pathology in Pulmonary TB [Phase 1]
A Phase 1 clinical trial evaluating 11C-acetate PET imaging as a novel approach to detect pathology in pulmonary tuberculosis.
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: PA-824-CL-007: Phase IIa Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis [Phase 2]
Phase IIa trial results for PA-824 (pretomanid) evaluating early bactericidal activity in pulmonary tuberculosis; the study completed and re…
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CLINICAL_TRIALS trial_result · 2017-02-14Clinical Trial Update: Line Probe Assay Evaluation Study
This clinical trial update reports completion of a study evaluating the performance of a line probe assay for detecting drug resistance in t…
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CLINICAL_TRIALS trial_result · 2016-12-13Clinical Trial Update: Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z) [Phase 2]
Phase 2 trial evaluating early bactericidal activity of a four-drug regimen (clofazimine, bedaquiline, pretomanid, and pyrazinamide) for pul…
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) (NC-002) [Phase 2]
Phase 2 study evaluating an 8-week regimen of moxifloxacin, pretomanid (PA-824), and pyrazinamide for drug-sensitive and multidrug-resistant…
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CLINICAL_TRIALS trial_result · 2016-10-17Clinical Trial Update: Efficacy and Safety of Qinbudan as an Adjunct Therapy for Retreatment Pulmonary Tuberculosis [Phase 2]
Phase 2 study assessing the efficacy and safety of Qinbudan as adjunct therapy for retreatment pulmonary tuberculosis has completed.
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: Prospective Assessment of TBDx Feasibility [NA]
The study completed a feasibility assessment of TBDx for diagnosing pulmonary tuberculosis. The update summarizes the trial status and outco…
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CLINICAL_TRIALS research · 2016-08-03Clinical Trial Update: Intervention in the Management of Post-high Tuberculosis Hospital Through Educational Strategy and Oversight Distance [NA]
A completed clinical trial from Hospital de Clinicas de Porto Alegre evaluating an educational strategy and oversight approach to managing t…
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CLINICAL_TRIALS research · 2016-05-11Clinical Trial Update: Diagnostic Trial to Validate the Use of the E-Nose in Pulmonary TB [NA]
A clinical trial led by Universidad Central de Venezuela is evaluating the e-Nose device for diagnosing pulmonary tuberculosis; the current …
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CLINICAL_TRIALS trial_result · 2016-04-01Clinical Trial Update: Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001) [Phase 2]
Phase 2 study evaluating early bactericidal activity in pulmonary tuberculosis using regimen J-M-Pa-Z (NC-001) has completed, with results p…
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CLINICAL_TRIALS trial_result · 2016-03-31Clinical Trial Update: Evaluation of the Practice of Three Morning Sputa on Separate Days for Diagnosis of Mtb
This completed trial evaluated whether collecting three morning sputum samples on separate days improves diagnosis of pulmonary tuberculosis…
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CLINICAL_TRIALS trial_result · 2016-03-09Clinical Trial Update: Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis (CL-010) [Phase 2]
Phase 2 clinical trial evaluating early bactericidal activity in pulmonary tuberculosis has completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-03-08Clinical Trial Update: SMF to Improve Performance of Microscopy for the Diagnosis of PTB in a High HIV Prevalence Setting
The trial completed evaluating smear microscopy fluorescence (SMF) to improve the performance of microscopy for diagnosing pulmonary tubercu…
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CLINICAL_TRIALS trial_result · 2016-02-05Clinical Trial Update: Immune Reconstitution in Tuberculosis Disease [Phase 2]
A Phase 2 clinical trial evaluating immune reconstitution strategies in pulmonary tuberculosis has completed.