Pulmonary Embolism
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Lung Scintigraphy for Pulmonary Embolism Diagnosis in COVID-19 Patients.
A completed clinical trial evaluating lung scintigraphy as a diagnostic tool for pulmonary embolism in patients with COVID-19.
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CLINICAL_TRIALS other · 2024-08-09Clinical Trial Update: Systemic Thrombolysis Versus Catheter Directed Management for Acute Intermediate-high Pulmonary Embolism
Clinical trial update comparing systemic thrombolysis with catheter-directed management for acute intermediate-high pulmonary embolism. The …
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Prognostic Model for Long-Term Cardiac Function After Pulmonary Embolism Based on Dynamic Electrocardial Signal and Circulating Biomarkers
This clinical trial aims to develop a prognostic model to predict long-term cardiac function after pulmonary embolism using dynamic electroc…
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CLINICAL_TRIALS withdrawal · 2024-07-22Clinical Trial Update: Predictive Value of Epicardial Adipose Tissue for Pulmonary Embolism and Death in Patients With Lung Cancer
A clinical trial evaluating whether epicardial adipose tissue can predict pulmonary embolism and death in patients with lung cancer has been…
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CLINICAL_TRIALS trial_result · 2024-07-19Clinical Trial Update: Evaluating the Safety and Efficacy of the AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 PE for Treatment of Acute Pulmonary Embolism [NA]
A completed clinical trial assessing the safety and efficacy of the AlphaVac Multipurpose Mechanical Aspiration device F1885 PE for acute pu…
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CLINICAL_TRIALS trial_result · 2024-07-18Clinical Trial Update: Pleth Variability Index in Pulmonary Embolism
A clinical trial evaluating Pleth Variability Index in patients with pulmonary embolism has completed.
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Alerting Providers at Patient Hospital Discharge to Consider Prescribing Rivaroxaban to Reduce Venous Thromboembolism [NA]
A clinical trial update describes a study to alert providers at hospital discharge to consider prescribing rivaroxaban to reduce venous thro…
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CLINICAL_TRIALS research · 2024-07-05Clinical Trial Update: Evaluation of the Standard Catheter-directed Thrombolysis Effectiveness in Intermediate-High-Risk Pulmonary Embolism Patients [NA]
This clinical trial update notes an ongoing study evaluating the effectiveness of catheter-directed thrombolysis in intermediate- to high-ri…
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: VTEval Project - Prospective Cohort Studies to Evaluate and Improve Diagnostics, Management Strategies and Risk Stratification in VTE
The VTEval Project is a prospective cohort study at Johannes Gutenberg University Mainz to evaluate diagnostics, management strategies, and …
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FDA approval · 2024-06-14FDA Approved: DABIGATRAN ETEXILATE — Original Application (Alembic Pharmaceuticals Inc.)
FDA approves Alembic Pharmaceuticals' Original Application for dabigatan etexilate as a generic version of Pradaxa, an oral anticoagulant in…
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CLINICAL_TRIALS research · 2024-06-13Clinical Trial Update: Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
A trial update describing the Acutelines biobank for acute and emergency medicine; recruitment is ongoing across multiple acute conditions.
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: The RAPID - PE Study: RESCUE Advanced Protocol for the Treatment of Pulmonary Embolism [NA]
A registry update for the RAPID-PE RESCUE Advanced Protocol study in pulmonary embolism; the trial is not yet recruiting.
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FDA approval · 2024-05-22FDA Approved: DABIGATRAN — Original Application (Novadoz Pharmaceuticals LLC)
FDA approved the original ANDA (ANDA213879) for DABIGATRAN (Dabigatan etexilate), a generic anticoagulant. The approval enables Novadoz Phar…
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CLINICAL_TRIALS research · 2024-05-17Clinical Trial Update: Inter-observer Reliability of the TRiP(Cast) Score in Patients With Trauma to a Lower Limb Requiring Immobilisation
A clinical trial is assessing how consistently different observers apply the TRiP(Cast) score in patients with lower-limb trauma requiring i…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Suture Closure AFtEr VEIN Access for Cardiac Procedures (SAFE-VEIN) Trial [NA]
The SAFE-VEIN trial evaluating suture closure after venous access for cardiac procedures has completed, with results posted in May 2024.
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: Changes of Cardiopulmonary Function After Thrombolysis in Patients With Pulmonary Embolism
This clinical trial update describes ongoing research evaluating changes in cardiopulmonary function after thrombolysis in patients with acu…
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CLINICAL_TRIALS trial_result · 2024-05-03Clinical Trial Update: Prevalence of Chronic Thromboembolic Pulmonary Hypertension After Acute Pulmonary Embolism : (Preva-CTEPH) [NA]
This entry summarizes the completed Preva-CTEPH clinical trial assessing the prevalence of chronic thromboembolic pulmonary hypertension aft…
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CLINICAL_TRIALS research · 2024-04-30Clinical Trial Update: Evaluation of the Effect of Drug-Related Problems in Pulmonary Embolism [NA]
The update summarizes a completed clinical study evaluating drug-related problems in patients with pulmonary embolism.
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CLINICAL_TRIALS withdrawal · 2024-03-08Clinical Trial Update: Macitentan to Prevent PRVO [Phase 3]
A Phase 3 trial evaluating macitentan to prevent pulmonary vascular events has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2024-02-08Clinical Trial Update: Efficacy and Safety of Half Dose Alteplase Added to Heparine, in Patients With Moderate Pulmonary Embolism [Phase 3]
A Phase 3 trial evaluating half-dose alteplase added to heparin for moderate pulmonary embolism was withdrawn.
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: Weight-Based Enoxaparin Dosing and Real-Time Dose Adjustment in Orthopaedic Trauma [Phase 2]
Phase 2 clinical trial evaluating weight-based enoxaparin dosing with real-time dose adjustment for orthopaedic trauma; study completed with…
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FDA approval · 2023-12-15FDA Approved: DABIGATRAN ETEXILATE — Original Application (Apotex Corp.)
FDA approved Apotex Corp.'s original application for dabigatran etexilate as a generic anticoagulant. The generic will have the same indicat…
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CLINICAL_TRIALS trial_result · 2023-12-12Clinical Trial Update: Apixaban in Preventing Secondary Cancer Related Venous Thrombosis in Cancer Patients Who Have Completed Anticoagulation Therapy [Phase 3]
A Phase 3 trial evaluated apixaban to prevent recurrent cancer-related venous thromboembolism in patients who completed initial anticoagulat…
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CLINICAL_TRIALS trial_result · 2023-11-28Clinical Trial Update: OsciPulse Device for the Prevention of VTE [NA]
Completed clinical trial of the OsciPulse device for prevention of venous thromboembolism with results posted in 2023.
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FDA approval · 2023-10-18FDA Approved: SAVAYSA — Supplemental Application (Daiichi Sankyo Inc.)
FDA approves a supplemental application for SAVAYSA (edoxaban tosylate) from Daiichi Sankyo, resulting in an update to the drug’s labeling.