Pulmonary Arterial Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: : Vascular Function in Health and Disease [Phase 1]
A Phase 1 trial evaluating vascular function in health and disease is currently recruiting, focusing on chronic obstructive pulmonary diseas…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Pulmonary Arterial Hypertension Improvement With Nutrition and Exercise (PHINE) [NA]
The Cleveland Clinic-sponsored clinical trial PHINE investigates whether nutrition and exercise can improve pulmonary arterial hypertension …
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: Pulmonary Hypertension Screening in Scleroderma
A clinical trial update indicates a study screening for pulmonary hypertension in patients with systemic sclerosis (scleroderma) is not yet …
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Pulmonary Arterial Hypertension and Associated Cardiovascular Disease Detection Using Artificial Intelligence
Imperial College London is conducting a clinical trial to evaluate AI-based detection of pulmonary arterial hypertension and associated card…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Right Ventricular Compensation With Sotatercept: A Prospective Single Arm Open Label Phase 4 Study to Evaluate the Effects of Sotatercept on Right Ventricular Function in Pulmonary Arterial Hypertension (RECOMPENSE) [Phase 4]
Phase 4 prospective, single-arm study evaluating the effects of sotatercept on right ventricular function in patients with pulmonary arteria…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Clinical Features and Prognosis of Takayasu's Arteritis With Pulmonary Arteries Involvement
A clinical trial investigating clinical features and prognosis of Takayasu arteritis with pulmonary artery involvement (including pulmonary …
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FDA approval · 2025-09-19FDA Approved: AMBRISENTAN — Supplemental Application (Apotex Corp.)
The FDA approved a supplemental application for ambrisentan from Apotex Corp., resulting in an approved update to its labeling under the exi…
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Vardenafil Inhaled for Pulmonary Arterial Hypertension PRN Phase 2B Study [Phase 2]
Respira Therapeutics completed a Phase 2B trial evaluating inhaled vardenafil for pulmonary arterial hypertension.
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Inspiratory Muscle Training in Pulmonary Hypertension [NA]
Completed clinical trial evaluating inspiratory muscle training in patients with pulmonary hypertension, including chronic thromboembolic pu…
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EMA approval · 2025-09-17EMA Authorised: Revatio (sildenafil) — Upjohn EESV
EMA authorised Revatio (sildenafil) for use in hypertension and pulmonary arterial hypertension, with Upjohn EESV as the marketing authoriza…
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CLINICAL_TRIALS trial_result · 2025-09-17Clinical Trial Update: Efficacy and Safety of Treprostinil in Intermediate-Risk Pulmonary Arterial Hypertension [Phase 2]
This clinical trial update discusses a Phase 2 study evaluating the efficacy and safety of treprostinil in patients with intermediate-risk p…
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Pharmacokinetics, Safety and Tolerability of Concurrent Doses of BIA 5-1058 and Furosemide [Phase 1]
Phase 1 study evaluating pharmacokinetics, safety and tolerability of concurrent dosing of BIA 5-1058 with furosemide in pulmonary arterial …
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Effects of Riociguat on RIght VEntricular Size and Function in PAH and CTEPH [Phase 4]
Phase 4 study assessing riociguat's effects on right ventricular size and function in pulmonary arterial hypertension and chronic thromboemb…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH) [Phase 3]
A Phase 3 trial in children with pulmonary arterial hypertension tests whether macitentan delays disease progression; the study has complete…
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: Study of ACT-293987 (NS-304) in Pulmonary Arterial Hypertension (PAH) [Phase 2]
This update reports the completion of a Phase 2 study of ACT-293987 (NS-304) for Pulmonary arterial hypertension conducted by Actelion.
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Home Rehabilitation Improves Cardiac Effort in Pulmonary Arterial Hypertension [NA]
This clinical trial entry discusses home rehabilitation as a potential approach for patients with Pulmonary Arterial Hypertension and shows …
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: The Risk of Adverse Pregnancy Outcomes for Long-term Exposure to Air Pollution in Pregnant Patients With Pulmonary Hypertension
This clinical trial, now completed, studied the risk of adverse pregnancy outcomes associated with long-term exposure to air pollution in pr…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Exercise-based Rehabilitation in Patients With Pulmonary Arterial Hypertension [NA]
An ongoing clinical trial evaluating exercise-based rehabilitation in patients with pulmonary arterial hypertension, currently recruiting at…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Satralizumab in the Treatment of Pulmonary Arterial Hypertension (SATISFY-JP Trial) [Phase 2]
A Phase 2 clinical trial (SATISFY-JP) evaluating satralizumab for pulmonary arterial hypertension is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Continuous Effect Of Rehabilitation Training On Pulmonary Arterial Hypertension Patients [NA]
A clinical trial is evaluating the continuous effect of rehabilitation training in patients with pulmonary arterial hypertension. The study …
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: Neuromodulation in Patients With Pulmonary Arterial Hypertension [Phase 1, Phase 2]
Update on a Phase 1/2 trial evaluating neuromodulation in pulmonary arterial hypertension; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-08-27Clinical Trial Update: A Study of HS235 for Treatment of Pulmonary Arterial Hypertension (PAH) in Adults [Phase 1]
This is a Phase 1 clinical trial evaluating HS235 for treatment of pulmonary arterial hypertension in adults; the study is not yet recruitin…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: COMPERA / COMPERA-KIDS
The COMPERA/COMPERA-KIDS registry sponsored by Technische Universität Dresden is currently recruiting participants to study pulmonary arteri…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Pulmonary Hypertension Institutional Registry at Hospital Italiano de Buenos Aires
This is a clinical trial registry update for the Pulmonary Hypertension Institutional Registry at Hospital Italiano de Buenos Aires, current…
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: A Study of Sotatercept in Participants With PAH WHO FC III or FC IV at High Risk of Mortality (MK-7962-006/ZENITH) [Phase 3]
Phase 3 trial MK-7962-006/ZENITH evaluating sotatercept in pulmonary arterial hypertension patients at high mortality risk has completed and…