Pulmonary Arterial Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008) [Phase 2]
A Phase 2 study is evaluating Sotatercept (MK-7962) in children with pulmonary arterial hypertension. The trial is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Sotatercept on Central Cardiopulmonary Performance and Peripheral Oxygen Transport During Exercise in Pulmonary Arterial Hypertension [Phase 4]
This Phase 4 clinical trial update summarizes results from a study of sotatercept assessing central cardiopulmonary performance and peripher…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY) [Phase 2]
A Phase 2 clinical trial update for ROC-101 in patients with pulmonary arterial hypertension and pulmonary hypertension due to interstitial …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Evolution of Hypoxic Burden and Sympathetic/Parasympathetic Balance in Patients With Pulmonary Hypertension [NA]
This clinical trial update indicates that the study on the evolution of hypoxic burden and autonomic balance in patients with precapillary p…
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FDA approval · 2026-04-14FDA Approved: BOSENTAN — Supplemental Application (Actavis Pharma, Inc.)
FDA approved a supplemental application for Bosentan from Actavis Pharma, Inc. The document indicates approval of a supplemental filing for …
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FDA approval · 2026-04-14FDA Approved: BOSENTAN — Supplemental Application (Zydus Pharmaceuticals USA Inc.)
The FDA approved a supplemental application for Bosentan filed by Zydus Pharmaceuticals USA Inc.
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients [Phase 3]
A Phase 3 trial evaluating Ralinepag for pulmonary arterial hypertension has completed; the update covers the study status and its efficacy …
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH) [Phase 2, Phase 3]
This clinical trial update describes an extension study of Treprostinil Palmitil Inhalation Powder (TPIP) for pulmonary arterial hypertensio…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
This entry describes a natural history study investigating biomarkers in pulmonary arterial hypertension, with recruitment currently ongoing…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: The Effects of Drug Candidate CS1 on Lung Structure and Function Utilizing FRI
A completed clinical trial evaluating the effects of drug candidate CS1 on lung structure and function using FRI in pulmonary arterial hyper…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension [Phase 3]
Phase 3 clinical trial evaluating selexipag as add-on therapy to standard of care for children with pulmonary arterial hypertension. The spo…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension [Phase 3]
This clinical trial update describes a Phase 3 outcome study evaluating a 75 mg dose of macitentan in patients with pulmonary arterial hyper…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA) [Phase 3]
Phase 3 PROSERA trial evaluating Seralutinib for pulmonary arterial hypertension has completed. The update covers efficacy and safety in adu…
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Open-label Extension Study of GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH) [Phase 2]
Open-label extension study of GB002 in adults with pulmonary arterial hypertension is ongoing, with the trial status listed as ACTIVE_NOT_RE…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Sotatercept in Pulmonary Arterial Hypertension [Phase 4]
Phase 4 trial update for Sotatercept in pulmonary arterial hypertension shows the study is currently recruiting. Sponsor is the University o…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Evaluation of the Efficacy and Safety of Oxacom® in Patients With Pulmonary Arterial Hypertension [Phase 2, Phase 3]
A clinical trial update on Oxacom evaluating efficacy and safety in patients with pulmonary arterial hypertension in Phase 2/3. The trial is…
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CLINICAL_TRIALS withdrawal · 2026-04-08Clinical Trial Update: Evaluation of the Pulmonary Vascular Reactivity Test in Patients With Pulmonary Arterial Hypertension and a Cardiac Shunt [NA]
A clinical trial evaluating the pulmonary vascular reactivity test in patients with pulmonary arterial hypertension and a congenital cardiac…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Endothelial Cell Dysfunction in Pulmonary Hypertension [Phase 1]
Phase 1 clinical trial investigating endothelial cell dysfunction in pulmonary hypertension has completed. The study focused on secondary pu…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: A Dose Escalation Study to Evaluate the Effect of RT234 in Subjects With Pulmonary Arterial Hypertension [Phase 2]
This is a Phase 2 dose-escalation study evaluating RT234 in subjects with pulmonary arterial hypertension. The study status is completed.
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Duke University-sponsored trial evaluating pharmacokinetics, pharmacodynamics, and safety of understudied drugs given to children as part of…
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FDA approval · 2026-04-03FDA Approved: TYVASO — Supplemental Application (United Therapeutics Corporation)
The FDA approved a supplemental application for Tyvaso (treprostinil) by United Therapeutics Corporation.
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Assessment of Right Ventricular Function by Cardiac MRI in Patients With Pulmonary Arterial Hypertension (IRMA)
A clinical trial evaluating right ventricular function in pulmonary arterial hypertension using cardiac MRI has completed, with the sponsor …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: ADAPT - A Patient Registry of the Real-world Use of Orenitram®
ADAPT is a patient registry tracking real-world use of Orenitram for pulmonary arterial hypertension.
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EMA approval · 2026-04-01EMA Authorised: Winrevair (sotatercept) — Merck Sharp & Dohme B.V.
The European Medicines Agency authorised Winrevair (sotatercept) from Merck Sharp & Dohme B.V. for pulmonary arterial hypertension and desig…
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FDA approval · 2026-04-01FDA Approved: BOSENTAN — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
The FDA approved a supplemental application for bosentan submitted by Sun Pharmaceutical Industries, Inc.