Pulmonary Arterial Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-04-08Clinical Trial Update: Crossover Study From Macitentan or Bosentan Over to Ambrisentan [Phase 4]
A phase 4 crossover study evaluating switching from macitentan or bosentan to ambrisentan in pulmonary arterial hypertension has been termin…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Aerobic Exercise Training in Pulmonary Arterial Hypertension [NA]
This entry notes the completed status of a clinical trial investigating aerobic exercise training in patients with pulmonary arterial hypert…
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CLINICAL_TRIALS trial_result · 2019-02-05Clinical Trial Update: A Pharmacokinetics Study for Pediatric Participants With Pulmonary Arterial Hypertension [Phase 1, Phase 2]
A pharmacokinetics study in pediatric participants with pulmonary arterial hypertension completed Phases 1 and 2, with results posted in 201…
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CLINICAL_TRIALS trial_result · 2019-01-04Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 Years [Phase 2]
Phase 2 trial evaluating safety, tolerability, and pharmacokinetics of oral treprostinil in pediatric pulmonary arterial hypertension patien…
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CLINICAL_TRIALS trial_result · 2018-12-03Clinical Trial Update: Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-005) [Phase 1]
Phase 1 trial assessing safety, tolerability, and pharmacokinetics of MK-8892 in participants with pulmonary arterial hypertension has compl…
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CLINICAL_TRIALS trial_result · 2018-10-31Clinical Trial Update: Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument [Phase 3]
A Phase 3 trial evaluating macitentan in pulmonary arterial hypertension to psychometrically validate the PAH-SYMPACT instrument has complet…
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CLINICAL_TRIALS trial_result · 2018-10-22Clinical Trial Update: Acute Dosing of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-003) [Phase 1]
Phase 1 trial update for acute dosing of MK-8892 in participants with pulmonary arterial hypertension (PAH) has been terminated; results pos…
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CLINICAL_TRIALS trial_result · 2018-09-26Clinical Trial Update: Comparative PK PD Study in PAH Patients (Fox vs. I-Neb) [Phase 1, Phase 2]
A comparative PK/PD study in pulmonary arterial hypertension patients comparing Fox with I-Neb across Phase 1 and Phase 2 is completed.
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CLINICAL_TRIALS trial_result · 2018-09-24Clinical Trial Update: Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH [Phase 2]
A Phase 2 clinical trial assessing the impact of inhaled nitric oxide on invasively derived pulmonary pressures in patients with pulmonary a…
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CLINICAL_TRIALS trial_result · 2018-08-22Clinical Trial Update: Clinical Study of Macitentan in Patients With PAH to Psychometrically Validate PAH-SYMPACT Instrument [Phase 3]
Phase 3 trial update for macitentan in pulmonary arterial hypertension focusing on psychometric validation of the PAH-SYMPACT instrument; st…
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CLINICAL_TRIALS trial_result · 2018-08-17Clinical Trial Update: Positron Emission Tomography (PET) Study to Evaluate Biodistribution of [11C]-GSK2256098 in Healthy Subjects and Idiopathic Pulmonary Arterial Hypertension (PAH) Patients [Phase 1]
Phase 1 PET biodistribution study evaluating [11C]-GSK2256098 in healthy subjects and pulmonary arterial hypertension patients; completed wi…
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CLINICAL_TRIALS trial_result · 2018-07-09Clinical Trial Update: Tezosentan in Patients With Pulmonary Arterial Hypertension [Phase 2]
A Phase 2 trial of tezosentan for pulmonary arterial hypertension was terminated.
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: First-line Bosentan and Sildenafil Combination Therapy for Pulmonary Arterial Hypertension
The document reports on a completed clinical trial evaluating first-line combination therapy with bosentan and sildenafil for pulmonary arte…
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CLINICAL_TRIALS trial_result · 2018-05-14Clinical Trial Update: Right Ventricular Pulmonary Vascular Interaction in Pulmonary Hypertension [NA]
This clinical trial update reports a completed study examining right ventricular–pulmonary vascular interactions in pulmonary arterial hyper…
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CLINICAL_TRIALS trial_result · 2018-05-04Clinical Trial Update: DelIVery for Pulmonary Arterial Hypertension (PAH) & Continued Support Study [NA]
Update on Medtronic's DelIVery trial for pulmonary arterial hypertension (PAH); the study is currently active but not recruiting, with resul…
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CLINICAL_TRIALS trial_result · 2018-04-19Clinical Trial Update: A Therapeutic Open Label Study of Tocilizumab in the Treatment of Pulmonary Arterial Hypertension [Phase 2]
Open-label Phase 2 trial evaluating tocilizumab for pulmonary arterial hypertension has completed.
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CLINICAL_TRIALS trial_result · 2018-04-13Clinical Trial Update: Rt Ventricular Substrate Metabolism as a Predictor of Rt Heart Failure in Patients With Pulmonary Arterial Hypertension [NA]
Clinical trial evaluating right ventricular substrate metabolism as a predictor of right heart failure in patients with pulmonary arterial h…
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CLINICAL_TRIALS trial_result · 2018-04-09Clinical Trial Update: Non-interventional Multi-center Study on Patients Under Routine Treatment of Pulmonary Arterial Hypertension (PAH) With Inhaled Iloprost Using I-Neb as a Device for Inhalation
A completed non-interventional, multi-center study evaluated routine inhaled iloprost therapy for pulmonary arterial hypertension delivered …
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CLINICAL_TRIALS trial_result · 2018-03-27Clinical Trial Update: BEET PAH: a Study to Assess the Effects of Beetroot Juice in Patients With Pulmonary Arterial Hypertension [NA]
The BEET PAH trial assessing the effects of beetroot juice in patients with pulmonary arterial hypertension has completed.
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CLINICAL_TRIALS trial_result · 2018-03-23Clinical Trial Update: Evaluation of Pulmonary Perfusion Heterogeneity and Compliance in Patients With Pulmonary Hypertension Using Positron Emission Tomography Imaging [NA]
A Massachusetts General Hospital clinical trial evaluating pulmonary perfusion heterogeneity and lung compliance in patients with pulmonary …
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CLINICAL_TRIALS trial_result · 2018-03-07Clinical Trial Update: Peripheral Muscle Microcirculation and Exercise-induced Blood Flow Distribution in Pulmonary Arterial Hypertension [NA]
A completed clinical trial examines peripheral muscle microcirculation and exercise-induced blood flow distribution in pulmonary arterial hy…
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: A Pulmonary Arterial Hypertension Study With Macitentan to Validate the PAH-SYMPACT™ in France, Italy and Spain [Phase 3]
Phase 3 study of macitentan to validate PAH-SYMPACT in France, Italy and Spain was terminated with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-01-30Clinical Trial Update: Clinical Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger Syndrome [Phase 3]
Phase 3 trial evaluating the effects of macitentan on exercise capacity in Eisenmenger syndrome completed with posted results in 2018.
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CLINICAL_TRIALS trial_result · 2018-01-18Clinical Trial Update: Effect of Morphine on Dyspnea and 6-Minute Walk Distance in Pulmonary Arterial Hypertension [Phase 2]
Phase 2 clinical trial evaluating the effect of morphine on dyspnea and 6-minute walk distance in patients with pulmonary arterial hypertens…
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CLINICAL_TRIALS trial_result · 2017-12-28Clinical Trial Update: Study to Assess the Tolerability and the Safety of the Transition From Inhaled Treprostinil to Oral Selexipag in Patients With Pulmonary Arterial Hypertension [Phase 3]
Phase 3 trial evaluating tolerability and safety of transitioning from inhaled treprostinil to oral selexipag in patients with pulmonary art…