Pulmonary Arterial Hypertension
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-06-16Clinical Trial Update: Beta-blockers in Pulmonary Arterial Hypertension [Phase 2]
Phase 2 trial assessing beta-blockers in pulmonary arterial hypertension was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: A Multi-Center, Open-Label, Multiple Dose, Dose Finding Study Exploring the Safety and Tolerability of Beraprost Sodium Modified Release in PAH Patients [Phase 2]
Phase 2 open-label, dose-finding study evaluating safety and tolerability of beraprost sodium modified release in pulmonary arterial hyperte…
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CLINICAL_TRIALS trial_result · 2020-04-30Clinical Trial Update: Early Treatment of Borderline Pulmonary Arterial Hypertension Associated With Systemic Sclerosis (SSc-APAH) [Phase 2]
Phase 2 trial update on early treatment of borderline pulmonary arterial hypertension associated with systemic sclerosis (SSc-APAH); study c…
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CLINICAL_TRIALS trial_result · 2020-04-21Clinical Trial Update: A Dose-escalation Study in Subjects With Pulmonary Arterial Hypertension (PAH) [Phase 2]
Phase 2 dose-escalation trial in pulmonary arterial hypertension (PAH) completed; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-03-23Clinical Trial Update: A Study of Tadalafil in Pediatric Participants With Pulmonary Arterial Hypertension (PAH) [Phase 3]
Phase 3 trial update for tadalafil in pediatric pulmonary arterial hypertension has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-02-28Clinical Trial Update: Beraprost-314d Added-on to Tyvaso® (BEAT) [Phase 3]
Phase 3 trial BEAT evaluating adding beraprost to Tyvaso in pulmonary arterial hypertension has completed with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-02-28Clinical Trial Update: Long-term Extension Study of the Safety and Pharmacokinetics of QCC374 in PAH Patients [Phase 2]
Long-term extension study of QCC374 in pulmonary arterial hypertension (Phase 2) was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-02-13Clinical Trial Update: Phase III Clinical Worsening Study of UT-15C in Subjects With PAH Receiving Background Oral Monotherapy [Phase 3]
Phase III trial update for UT-15C in pulmonary arterial hypertension; study completed with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-02-05Clinical Trial Update: Effect of Pharmacologic Interaction Between ERAs and PDE-5 Inhibitors on Medication Serum Levels and Clinical Disease Status in Patients With PAH
A completed clinical trial evaluated how pharmacologic interactions between ERA therapies and PDE-5 inhibitors affect drug serum levels and …
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CLINICAL_TRIALS trial_result · 2019-12-26Clinical Trial Update: An Open-Label Extension of BPS-MR-PAH-201 in Pulmonary Arterial Hypertension (PAH) Patients [Phase 2]
Open-label extension study of BPS-MR-PAH-201 in pulmonary arterial hypertension completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-12-09Clinical Trial Update: Estrogen Receptor Antagonist in Patients With Pulmonary Arterial Hypertension [Phase 2]
Phase 2 clinical trial evaluating an estrogen receptor antagonist in patients with pulmonary arterial hypertension has completed with posted…
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CLINICAL_TRIALS trial_result · 2019-11-15Clinical Trial Update: The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study [Phase 4]
Phase 4 trial investigating ambrisentan in combination with spironolactone for pulmonary arterial hypertension has been terminated with resu…
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CLINICAL_TRIALS trial_result · 2019-10-08Clinical Trial Update: Clinical Study Evaluating the Effects of First-line Oral cOmbination theraPy of maciTentan and tadalafIl in Patients With Newly Diagnosed pulMonary Arterial Hypertension (OPTIMA) [Phase 4]
Phase 4 clinical trial evaluating first-line combination therapy of macitentan and tadalafil in newly diagnosed pulmonary arterial hypertens…
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CLINICAL_TRIALS trial_result · 2019-10-07Clinical Trial Update: Fluoxetine in Pulmonary Arterial Hypertension (PAH) Trial [Phase 2]
A Phase 2 clinical trial evaluating fluoxetine for pulmonary arterial hypertension has completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-10-03Clinical Trial Update: The Role of Trimetazidine on Right Ventricle Function in Pulmonary Arterial Hypertension [Phase 2, Phase 3]
A clinical trial evaluating trimetazidine for right ventricular function in precapillary pulmonary hypertension has completed Phase 2 and Ph…
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CLINICAL_TRIALS trial_result · 2019-09-16Clinical Trial Update: Extension of BPS-MR-PAH-203 in Pulmonary Arterial Hypertension (PAH) Patients [Phase 2]
A Phase 2 extension study update for BPS-MR-PAH-203 in patients with pulmonary arterial hypertension (PAH).
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CLINICAL_TRIALS trial_result · 2019-08-13Clinical Trial Update: Clinical Study of Adipose Derived Mesenchymal Stem Cells for Treatment of Pulmonary Arterial Hypertension [Phase 1, Phase 2]
A clinical trial investigating adipose-derived mesenchymal stem cells for pulmonary arterial hypertension across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2019-08-07Clinical Trial Update: Safety, Pharmacokinetics and Efficacy Study of QCC374 in PAH Patients [Phase 2]
Phase 2 trial update on QCC374 in pulmonary arterial hypertension (terminated; results posted).
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CLINICAL_TRIALS trial_result · 2019-07-22Clinical Trial Update: A Rising Single Dose Study of the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics of MK-8892 (MK-8892-001) [Phase 1]
Phase 1 single-dose study of MK-8892 in healthy or PAH populations to assess safety, tolerability, PK and PD; completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-07-05Clinical Trial Update: Effect of Sildenafil for Sustained PAH After MV Surgery (SUPERIOR Trial) [Phase 2, Phase 3]
Clinical trial update for the SUPERIOR trial evaluating sildenafil for sustained pulmonary arterial hypertension after mitral valve surgery;…
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CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: Open-label, Multi-center Protocol to Provide QTI571 to PAH Patients Who Participated in the Extension Study (A2301E1) in Japan [Phase 3]
Phase 3 open-label trial update for QTI571 (selexipag? or QTI571) provided to PAH patients who participated in an extension study in Japan; …
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CLINICAL_TRIALS trial_result · 2019-05-22Clinical Trial Update: Safety and Efficacy of Fluoxetine in Pulmonary Arterial Hypertension [Phase 2]
Phase 2 clinical trial assessing safety and efficacy of fluoxetine in pulmonary arterial hypertension has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-05-21Clinical Trial Update: Safety Study of the Switch From Oral Selexipag to Intravenous Selexipag in Subjects With Stable Pulmonary Arterial Hypertension [Phase 3]
This is a Phase 3 safety study evaluating switching from oral selexipag to intravenous selexipag in patients with stable pulmonary arterial …
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: Clinical Study to Assess the Long-term Safety, Tolerability, and Efficacy of Macitentan in Subjects With Eisenmenger Syndrome [Phase 3]
Phase 3 trial assessing long-term safety, tolerability, and efficacy of macitentan in Eisenmenger syndrome; study terminated with results po…
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CLINICAL_TRIALS trial_result · 2019-04-10Clinical Trial Update: Selonsertib in Adults With Pulmonary Arterial Hypertension [Phase 2]
Phase 2 clinical trial update for Selonsertib in adults with Pulmonary Arterial Hypertension has completed enrollment with results posted.